Immunoglobulin G Levels in the Gingival Crevicular Fluid of Menopausal Patients with Periodontitis
Andrianus, Edmond Pradipta; Masulili, Sri Lelyati C; Lessang, Robert; Tadjoedin, Fatimah Maria; Hutomo, Dimas Ilham; Wulandari, Pitu; Auerkari, Elza Ibrahim.
Pesqui. bras. odontopediatria clín. integr
; 21: e5940, 2021. tab
Artigo
em Inglês
| LILACS, BBO - odontologia (Brasil) | ID: biblio-1250459
Abstract
Objective:
To measure the level of immunoglobulin G (IgG) in the gingival crevicular fluid (GCF). Material andMethods:
A total of 158 patients aged >45 years were examined for periodontitis and interviewed regarding their menopausal status. The non-menopause group entailed female patients with periodontitis without menopause (n=23). The menopause group included females who stopped menstruating since >1 year, had a pocket depth of 4-5 mm, and did not have other systemic conditions (n=40). Samples were selected based on periodontal and menopausal status. In total, 63 samples of GCF were collected from the participants and tested using an enzyme-linked immunosorbent assay kit for IgG.Results:
The median level of IgG in the menopause group was 39.50 (g/mL, whereas that of the non-menopause group was 41.08 (g/mL. There was a positive correlation between the plaque index and IgG level in both groups. In contrast, there was a negative correlation between age and IgG level. However, there was no correlation between plaque index and age regarding the IgG level in both groups (p>0.05).Conclusion:
The IgG levels in the menopause group were lower than those in the non-menopause group. As such, menopausal females should take great care of their overall health, including the periodontium.
Biblioteca responsável:
BR1264.1
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