Fabrication improvements for thermoset polyester (TPE) microfluidic devices.
Lab Chip
; 7(7): 923-6, 2007 Jul.
Article
em En
| MEDLINE
| ID: mdl-17594014
ABSTRACT
Thermoset polyester (TPE) microfluidic devices were previously developed as an alternative to poly(dimethylsiloxane) (PDMS) devices, fabricated similarly by replica molding, yet offering stable surface properties and good chemical compatibility with some organics that are incompatible with PDMS. This paper describes a number of improvements in the fabrication of TPE chips. Specifically, we describe methods to form TPE devices with a thin bottom layer for use with high numerical aperture (NA) objectives for sensitive fluorescence detection and optical manipulation. We also describe plasma-bonding of TPE to glass to create hybrid TPE-glass devices. We further present a simple master-pretreatment method to replace our original technique that required the use of specialized equipment.
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Base de dados:
MEDLINE
Assunto principal:
Poliésteres
/
Silicones
/
Microfluídica
/
Técnicas Analíticas Microfluídicas
/
Dimetilpolisiloxanos
Idioma:
En
Revista:
Lab Chip
Assunto da revista:
BIOTECNOLOGIA
/
QUIMICA
Ano de publicação:
2007
Tipo de documento:
Article
País de afiliação:
Estados Unidos