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Histologic and clinical evaluation for maxillary sinus augmentation using macroporous biphasic calcium phosphate in human.

Lee, Ji Hyun; Jung, Ui Won; Kim, Chang Sung; Choi, Seong Ho; Cho, Kyoo Sung.
Clin Oral Implants Res; 19(8): 767-71, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-18705808

OBJECTIVES:

This study evaluated both the clinical and histological aspects of bone formation in maxillary sinus augmentation using MBCP as the bone-grafting material. MATERIAL AND

METHODS:

MBCP was used as a primary bone substitute for maxillary sinus augmentation. Fifty-two patients were selected after a medical and dental examination, and were divided into the following three groups those augmented with MBCP only; MBCP combined with irradiated cancellous bone; and MBCP combined with intraoral autogenous bone. After a healing period (average 6.78 months after surgery), bone cores were harvested for a histological evaluation and the implant fixtures were installed. These bone cores were evaluated via light microscope and implants were followed up for at least six months after loading.

RESULTS:

Four to ten months after surgery, new vital bone surrounding the MBCP particles was observed in 18 bone biopsies. Two out of the 130 implants installed were explanted due to a failure of osseointegration before the prosthetic procedure. All the remaining implants were functioning for 6 to 27 months (average 12.96 months). The cumulative survival rate of the implants was 98.46%.

CONCLUSION:

These results show that MBCP can be used as a grafting material for sinus floor augmentation, whether combined with other bone graft materials or not, and lead to a predictable prognosis for dental implants in the posterior maxillary area where there is insufficient vertical height for fixture installation.