Pharmacokinetic and tissue distribution of paclitaxel in rabbits assayed by LC-UV after intravenous administration of its novel liposomal formulation.

Wei, Yumeng; Xue, Zhengkai; Ye, Yun; Wang, Peng; Huang, Yu; Zhao, Ling

Wei, Yumeng; Xue, Zhengkai; Ye, Yun; Wang, Peng; Huang, Yu; Zhao, Ling.

Afiliação

Wei Y; Department of Pharmaceutical Sciences, School of Pharmacy, Luzhou Medical University, No. 3-319, Zhongshan Road, Jiangyang District, Luzhou city, Sichuan Province, 646000, People's Republic of China; Drug and Functional Food Research Center, Luzhou Medical University, No. 3-319, Zhongshan Road, Jiangyang District, Luzhou city, Sichuan Province, 646000, People's Republic of China.

Biomed Chromatogr ; 28(2): 204-12, 2014 Feb.

Article em En | MEDLINE | ID: mdl-23893887

Assuntos

Lipossomos/sangue; Lipossomos/farmacocinética; Paclitaxel/sangue; Paclitaxel/farmacocinética; Animais; Cromatografia Líquida de Alta Pressão; Estabilidade de Medicamentos; Modelos Lineares; Lipossomos/química; Paclitaxel/química; Paclitaxel/isolamento & purificação; Coelhos; Reprodutibilidade dos Testes; Sensibilidade e Especificidade; Distribuição Tecidual

Palavras-chave

LC-UV; bio-distribution; novel lung targeting liposomes; paclitaxel; pharmacokinetics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Paclitaxel / Lipossomos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Animals Idioma: En Revista: Biomed Chromatogr Ano de publicação: 2014 Tipo de documento: Article

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