Blot-immunobinding test for the detection of anti-sperm antibodies.
J Reprod Immunol
; 8(4): 329-36, 1985 Dec.
Article
em En
| MEDLINE
| ID: mdl-2422372
ABSTRACT
A blot-immunobinding test was used to detect anti-sperm antibodies in human sera and to identify the corresponding auto- or iso-antigens on human sperm. A high proportion of sera at a 1100 dilution from fertile persons, as well as infertile patients, contains antibodies reactive with sperm. This phenomenon might be physiological. At 12,000 dilution, a higher binding capacity was detected in the sera from infertile groups, but a few fertile persons were also positive. Antibodies to a single antigenic determinant with Mr of approximately 14,000 were found in a significantly higher proportion among males with unexplained infertility.
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Base de dados:
MEDLINE
Assunto principal:
Espermatozoides
/
Anticorpos
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Reprod Immunol
Ano de publicação:
1985
Tipo de documento:
Article