Role of Electrostatic Interactions on the Transport of Druglike Molecules in Hydrogel-Based Articular Cartilage Mimics: Implications for Drug Delivery.

Ye, Fengbin; Baldursdottir, Stefania; Hvidt, Søren; Jensen, Henrik; Larsen, Susan W; Yaghmur, Anan; Larsen, Claus; Østergaard, Jesper

Ye, Fengbin; Baldursdottir, Stefania; Hvidt, Søren; Jensen, Henrik; Larsen, Susan W; Yaghmur, Anan; Larsen, Claus; Østergaard, Jesper.

Afiliação

Ye F; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Baldursdottir S; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Hvidt S; Department of Chemistry-NSM, Roskilde University , Universitetsvej 1, DK-4000 Roskilde, Denmark.
Jensen H; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Larsen SW; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Yaghmur A; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Larsen C; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken 2, DK-2100 Copenhagen, Denmark.
Østergaard J; Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen , Universitetsparken 2, DK-2100 Copenhagen, Denmark.

Mol Pharm ; 13(3): 819-28, 2016 Mar 07.

Article em En | MEDLINE | ID: mdl-26808484

Assuntos

Biomimética; Cartilagem Articular/química; Sistemas de Liberação de Medicamentos; Hidrogel de Polietilenoglicol-Dimetacrilato/química; Naftalenos/farmacocinética; Animais; Bovinos; Sulfatos de Condroitina/química; Ácido Hialurônico/química; Lactalbumina/química; Muramidase/química; Naftalenos/química; Reologia; Espectrofotometria Ultravioleta; Eletricidade Estática; Engenharia Tecidual

Palavras-chave

UV imaging; cartilage mimic; chondroitin sulfate; diffusion; drug delivery; electrostatic interactions; hyaluronic acid; hydrogel; transport

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cartilagem Articular / Sistemas de Liberação de Medicamentos / Hidrogel de Polietilenoglicol-Dimetacrilato / Biomimética / Naftalenos Limite: Animals Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Dinamarca

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