Amphiphilic core-shell nanoparticles containing dense polyethyleneimine shells for efficient delivery of microRNA to Kupffer cells.

Liu, Zuojin; Niu, Dechao; Zhang, Junyong; Zhang, Wenfeng; Yao, Yuan; Li, Pei; Gong, Jianping

Liu, Zuojin; Niu, Dechao; Zhang, Junyong; Zhang, Wenfeng; Yao, Yuan; Li, Pei; Gong, Jianping.

Afiliação

Liu Z; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Niu D; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China; Lab of Low-Dimensional Materials Chemistry, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, P
Zhang J; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Zhang W; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Yao Y; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China.
Li P; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, People's Republic of China.
Gong J; Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.

Int J Nanomedicine ; 11: 2785-97, 2016.

Article em En | MEDLINE | ID: mdl-27366061

Assuntos

Técnicas de Transferência de Genes; Células de Kupffer/metabolismo; MicroRNAs/administração & dosagem; Nanopartículas/química; Polietilenoimina/química; Tensoativos/química; Animais; Western Blotting; Morte Celular; Sobrevivência Celular; Ensaio de Imunoadsorção Enzimática; Humanos; Imuno-Histoquímica; Masculino; Camundongos Endogâmicos C57BL; MicroRNAs/metabolismo; NF-kappa B/metabolismo; Nanopartículas/ultraestrutura; Plasmídeos/metabolismo; Polimetil Metacrilato/química; Transfecção

Palavras-chave

Kupffer cells; amphiphilic core-shell nanoparticles; branched polyethyleneimine; gene delivery

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Polietilenoimina / Tensoativos / Técnicas de Transferência de Genes / MicroRNAs / Nanopartículas / Células de Kupffer Limite: Animals / Humans / Male Idioma: En Revista: Int J Nanomedicine Ano de publicação: 2016 Tipo de documento: Article

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