Design and Evaluation of Topical Diclofenac Sodium Gel Using Hot Melt Extrusion Technology as a Continuous Manufacturing Process with Kolliphor® P407.

Pawar, Jaywant; Narkhede, Rajkiran; Amin, Purnima; Tawde, Vaishali

Pawar, Jaywant; Narkhede, Rajkiran; Amin, Purnima; Tawde, Vaishali.

Afiliação

Pawar J; BASF India Ltd, Pharma Solutions, Plot No. 12, TTC Area, Thane Belapur Road, Turbhe, Navi Mumbai, 400705, India. jaywantpawar.ict@gmail.com.
Narkhede R; Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, University under Section-3 of UGC Act-1956, Elite Status & Centre of Excellence - Govt. of Maharashtra, N. P. Marg, Matunga, Mumbai, 400019, India. jaywantpawar.ict@gmail.com.
Amin P; BASF India Ltd, Pharma Solutions, Plot No. 12, TTC Area, Thane Belapur Road, Turbhe, Navi Mumbai, 400705, India.
Tawde V; Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai, University under Section-3 of UGC Act-1956, Elite Status & Centre of Excellence - Govt. of Maharashtra, N. P. Marg, Matunga, Mumbai, 400019, India.

AAPS PharmSciTech ; 18(6): 2303-2315, 2017 Aug.

Article em En | MEDLINE | ID: mdl-28108974

Assuntos

Diclofenaco/administração & dosagem; Tecnologia Farmacêutica; Administração Cutânea; Diclofenaco/química; Estabilidade de Medicamentos; Géis; Polietilenoglicóis/química; Solubilidade

Palavras-chave

diclofenac sodium; gel; hot melt extrusion; kolliphor® P407; kollisolv® PEG 400; stability; texture analyzer

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diclofenaco / Tecnologia Farmacêutica Idioma: En Revista: AAPS PharmSciTech Assunto da revista: FARMACOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia

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