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Primary Intraosseous Adenoid Cystic Carcinoma of the Mandible: A Comprehensive Review With Analysis of 2 Additional Cases.

Hu, Hong Ying; Liu, Yuan Yuan; Wang, Hu; Jiang, Meng.
J Oral Maxillofac Surg; 75(8): 1685-1701, 2017 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-28193443

PURPOSE:

Primary intraosseous adenoid cystic carcinoma (IACC) of the mandible is poorly understood because of its rarity. This study performed a comprehensive literature review on IACC of the mandible.

MATERIALS AND METHODS:

Forty-five cases of IACC reported in the literature and 2 additional cases in the authors' hospital were reviewed.

RESULTS:

IACC of the mandible generally occurred in the fourth to sixth decades, with no meaningful gender predilection. Pain and swelling were the most common clinical manifestations. Radical surgery combined with postsurgical radiotherapy was recommended as the best treatment.

CONCLUSIONS:

The diagnosis of IACC should be based on clinical, radiologic, and pathologic examinations. Radical surgery combined with postsurgical radiotherapy seems to be the best treatment. In addition, the histologic subtype of the tumor is an important prognostic factor in patients with IACC.