Effects of poly(I:C) and MF59 co-adjuvants on immunogenicity and efficacy of survivin polypeptide immunogen against melanoma.

Jiang, Xiaoyu; Guan, Shanshan; Qiao, Yongbo; Li, Xiao; Xu, Yan; Yang, Lan; Kuai, Ziyu; Zhang, Haihong; Shi, Yuhua; Kong, Wei; Shan, Yaming; Zhang, Hao

Jiang, Xiaoyu; Guan, Shanshan; Qiao, Yongbo; Li, Xiao; Xu, Yan; Yang, Lan; Kuai, Ziyu; Zhang, Haihong; Shi, Yuhua; Kong, Wei; Shan, Yaming; Zhang, Hao.

Afiliação

Jiang X; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Guan S; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Qiao Y; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Li X; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Xu Y; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Yang L; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Kuai Z; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Zhang H; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Shi Y; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Kong W; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Shan Y; Key Laboratory for Molecular Enzymology and Engineering, The Ministry of Education, School of Life Sciences, Jilin University, Changchun, Jilin, China.
Zhang H; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, Jilin, China.

J Cell Physiol ; 233(6): 4926-4934, 2018 06.

Article em En | MEDLINE | ID: mdl-29206298

Assuntos

Adjuvantes Imunológicos/farmacologia; Vacinas Anticâncer/farmacologia; Melanoma Experimental/tratamento farmacológico; Fragmentos de Peptídeos/imunologia; Poli I-C/farmacologia; Polissorbatos/farmacologia; Neoplasias Cutâneas/tratamento farmacológico; Esqualeno/farmacologia; Survivina/imunologia; Animais; Vacinas Anticâncer/síntese química; Vacinas Anticâncer/imunologia; Linhagem Celular Tumoral; Proliferação de Células/efeitos dos fármacos; Citotoxicidade Imunológica/efeitos dos fármacos; Epitopos; Feminino; Imunidade Celular/efeitos dos fármacos; Imunidade Humoral/efeitos dos fármacos; Imunogenicidade da Vacina; Ativação Linfocitária/efeitos dos fármacos; Melanoma Experimental/imunologia; Melanoma Experimental/patologia; Camundongos Endogâmicos C57BL; Fragmentos de Peptídeos/síntese química; Poli I-C/imunologia; Neoplasias Cutâneas/imunologia; Neoplasias Cutâneas/patologia; Esqualeno/imunologia; Linfócitos T/efeitos dos fármacos; Linfócitos T/imunologia; Carga Tumoral/efeitos dos fármacos

Palavras-chave

MF59; adjuvant combination; peptide vaccine; poly(I:C); survivin epitope peptide

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Polissorbatos / Neoplasias Cutâneas / Esqualeno / Melanoma Experimental / Adjuvantes Imunológicos / Poli I-C / Vacinas Anticâncer / Survivina Limite: Animals Idioma: En Revista: J Cell Physiol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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