Identification of a unique receptor on a group A streptococcus for the Fc region of human IgG3.
J Immunol
; 136(7): 2670-3, 1986 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-2936826
ABSTRACT
Receptors that bind to the Fc region of all four human IgG subclasses have been described on a number of strains of group A streptococci. In this study, we have demonstrated that these immunoglobulin binding properties are mediated by two distinct Fc receptors. The first receptor, with a Mr of approximately 56,000, binds to human IgG1, IgG2, and IgG4, but not to IgG3. A second receptor, with a Mr of approximately 38,000, binds exclusively to human immunoglobulins of the IgG3 subclass.
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Base de dados:
MEDLINE
Assunto principal:
Streptococcus pyogenes
/
Imunoglobulina G
/
Receptores Fc
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Immunol
Ano de publicação:
1986
Tipo de documento:
Article