Use of polyphenols as a strategy to prevent bond degradation in the dentin-resin interface.
Eur J Oral Sci
; 126(2): 146-158, 2018 04.
Article
em En
| MEDLINE
| ID: mdl-29380895
ABSTRACT
This study evaluated the effect of dentin pretreatment with the polyphenols quercetin and resveratrol on the resin-dentin microtensile bonding strength (µTBS) and collagen fibrils stability of the adhesive interface. Different concentrations (100, 250, 500, or 1,000 µg ml-1 ) of quercetin or resveratrol, or a mixture of quercetin and resveratrol (31, 11, 13; volvol), as well as distilled water or 2% chlorhexidine digluconate, were applied to etched dentin. Then, a two-step etch-and-rinse adhesive was applied followed by composite restoration. Measurements of resin-dentin µTBS were made after 1 and 120 d. The stability of collagen fibrils in the hybrid layer was evaluated using transmission electron microscopy. The Student's t-test and two-way factorial anova with Tukey's test were used to analyze the effects of dentin pretreatment and storage time on µTBS values. Comparisons between µTBS measurements made on 1 and 120 d showed that resveratrol had the best performance, with significantly higher µTBS values after 120 d for all concentrations of resveratrol tested. Quercetin pretreatment resulted in a significant rise of µTBS when used at concentrations of 100 and 500 µg ml-1 . Quercetin + resveratrol at the ratio of 11 performed better than when used at ratios of either 31 or 13. Resveratrol might represent a potential approach to achieve desirable bonding stability and reduce the frequent replacement of composite restorations.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quercetina
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Resinas Sintéticas
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Resistência à Tração
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Adesivos Dentinários
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Análise do Estresse Dentário
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Dentina
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Resveratrol
Idioma:
En
Revista:
Eur J Oral Sci
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil