Optimization of the Preparation Conditions of Borneol-Modified Ginkgolide Liposomes by Response Surface Methodology and Study of Their Blood Brain Barrier Permeability.

Lv, Zhiyang; Yang, Yuwei; Wang, Jie; Chen, Jing; Li, Junsong; Di, Liuqing

Lv, Zhiyang; Yang, Yuwei; Wang, Jie; Chen, Jing; Li, Junsong; Di, Liuqing.

Afiliação

Lv Z; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210046, China. lvzhiyang83@163.com.
Yang Y; Hanlin College, Nanjing University of Chinese Medicine, Taizhou 225300, China. lvzhiyang83@163.com.
Wang J; Jiangsu Engineering Research Center for Efficient Delivery System of TCM, Nanjing 210046, China. lvzhiyang83@163.com.
Chen J; Nanjing Engineering Research Center for Industrialization of Chinese Medicine Pellets, Nanjing 210046, China. lvzhiyang83@163.com.
Li J; Hanlin College, Nanjing University of Chinese Medicine, Taizhou 225300, China. hlxynursing@163.com.
Di L; Hanlin College, Nanjing University of Chinese Medicine, Taizhou 225300, China. wangjie199084@126.com.

Molecules ; 23(2)2018 Jan 31.

Article em En | MEDLINE | ID: mdl-29385087

Assuntos

Barreira Hematoencefálica/metabolismo; Canfanos; Células Endoteliais/metabolismo; Ginkgolídeos; Animais; Barreira Hematoencefálica/patologia; Canfanos/química; Canfanos/farmacocinética; Canfanos/farmacologia; Linhagem Celular Transformada; Células Endoteliais/patologia; Ginkgolídeos/química; Ginkgolídeos/farmacocinética; Ginkgolídeos/farmacologia; Lipossomos; Camundongos; Permeabilidade

Palavras-chave

blood-brain barrier permeability; borneol; ginkgolides; liposome; response surface methodology

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Canfanos / Barreira Hematoencefálica / Células Endoteliais / Ginkgolídeos Limite: Animals Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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