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Cancer-secreted hsa-miR-940 induces an osteoblastic phenotype in the bone metastatic microenvironment via targeting ARHGAP1 and FAM134A.
Hashimoto, Kyoko; Ochi, Hiroki; Sunamura, Satoko; Kosaka, Nobuyoshi; Mabuchi, Yo; Fukuda, Toru; Yao, Kenta; Kanda, Hiroaki; Ae, Keisuke; Okawa, Atsushi; Akazawa, Chihiro; Ochiya, Takahiro; Futakuchi, Mitsuru; Takeda, Shu; Sato, Shingo.
Afiliação
  • Hashimoto K; Department of Physiology and Cell Biology, Tokyo Medical and Dental University (TMDU), Graduate School, 113-8510 Tokyo, Japan.
  • Ochi H; Department of Physiology and Cell Biology, Tokyo Medical and Dental University (TMDU), Graduate School, 113-8510 Tokyo, Japan.
  • Sunamura S; Department of Physiology and Cell Biology, Tokyo Medical and Dental University (TMDU), Graduate School, 113-8510 Tokyo, Japan.
  • Kosaka N; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 104-0045 Tokyo, Japan.
  • Mabuchi Y; Department of Biochemistry and Biophysics, Tokyo Medical and Dental University (TMDU), Graduate School, 113-8510 Tokyo, Japan.
  • Fukuda T; Department of Food Science, Tokyo Seiei College, 124-8530 Tokyo, Japan.
  • Yao K; Department of Physiology and Cell Biology, Tokyo Medical and Dental University (TMDU), Graduate School, 113-8510 Tokyo, Japan.
  • Kanda H; Department of Pathology, The Cancer Institute of the Japanese Foundation for Cancer Research, 135-8550 Tokyo, Japan.
  • Ae K; Department of Orthopaedic Oncology, Cancer Institute Ariake Hospital, 135-8550 Tokyo, Japan.
  • Okawa A; Department of Orthopaedic Surgery, Tokyo Medical and Dental University (TMDU), Graduate School, 113-8510 Tokyo, Japan.
  • Akazawa C; Department of Biochemistry and Biophysics, Tokyo Medical and Dental University (TMDU), Graduate School, 113-8510 Tokyo, Japan.
  • Ochiya T; Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 104-0045 Tokyo, Japan.
  • Futakuchi M; Department of Pathology, Nagasaki University Graduate School of Biomedical Sciences, 852-8523 Nagasaki, Japan.
  • Takeda S; Division of Endocrinology, Toranomon Hospital Endocrine Center, 105-8470 Tokyo, Japan takeda.phy2@tmd.ac.jp satoshin.phy2@tmd.ac.jp.
  • Sato S; Department of Physiology and Cell Biology, Tokyo Medical and Dental University (TMDU), Graduate School, 113-8510 Tokyo, Japan; takeda.phy2@tmd.ac.jp satoshin.phy2@tmd.ac.jp.
Proc Natl Acad Sci U S A ; 115(9): 2204-2209, 2018 02 27.
Article em En | MEDLINE | ID: mdl-29440427
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Neoplasias Ósseas / Neoplasias da Mama / Proteínas Ativadoras de GTPase / MicroRNAs / Proteínas de Membrana Limite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Neoplasias Ósseas / Neoplasias da Mama / Proteínas Ativadoras de GTPase / MicroRNAs / Proteínas de Membrana Limite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão