Formulation in DDA-MPLA-TDB Liposome Enhances the Immunogenicity and Protective Efficacy of a DNA Vaccine against <i>Mycobacterium tuberculosis</i> Infection.

Tian, Maopeng; Zhou, Zijie; Tan, Songwei; Fan, Xionglin; Li, Longmeng; Ullah, Nadeem

Formulation in DDA-MPLA-TDB Liposome Enhances the Immunogenicity and Protective Efficacy of a DNA Vaccine against Mycobacterium tuberculosis Infection.

Tian, Maopeng; Zhou, Zijie; Tan, Songwei; Fan, Xionglin; Li, Longmeng; Ullah, Nadeem.

Afiliação

Tian M; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Zhou Z; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Tan S; Tongji School of Pharmacy, National Engineering Research Center for Nanomedicine, Huazhong University of Science and Technology, Wuhan, China.
Fan X; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li L; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ullah N; Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Front Immunol ; 9: 310, 2018.

Article em En | MEDLINE | ID: mdl-29535714

Assuntos

Imunogenicidade da Vacina; Mycobacterium tuberculosis/imunologia; Vacinas contra a Tuberculose; Tuberculose Pulmonar/imunologia; Tuberculose Pulmonar/prevenção & controle; Vacinas de DNA; Animais; Feminino; Lipossomos; Camundongos; Mycobacterium tuberculosis/genética; Vacinas contra a Tuberculose/química; Vacinas contra a Tuberculose/imunologia; Vacinas contra a Tuberculose/farmacologia; Tuberculose Pulmonar/genética; Tuberculose Pulmonar/patologia; Vacinas de DNA/química; Vacinas de DNA/imunologia; Vacinas de DNA/farmacologia

Palavras-chave

DNA vaccine; adjuvant; dimethyldioctadecylammonium; liposome; monophosphoryl lipid A; trehalose 6,6'-dibehenate; tuberculosis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tuberculose Pulmonar / Vacinas de DNA / Vacinas contra a Tuberculose / Imunogenicidade da Vacina / Mycobacterium tuberculosis Limite: Animals Idioma: En Revista: Front Immunol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

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