Investigation on absorption and release of mercaptopurine anticancer drug from modified polylactic acid as polymer carrier by molecular dynamic simulation.

Iesavand, Homa; Rahmati, Mahmoud; Afzali, Dariush; Modiri, Sina

Iesavand, Homa; Rahmati, Mahmoud; Afzali, Dariush; Modiri, Sina.

Afiliação

Iesavand H; Department of Chemical Engineering, Graduate University of Advanced Technology, Kerman, Iran.
Rahmati M; Department of Chemical Engineering, Graduate University of Advanced Technology, Kerman, Iran. Electronic address: m.rahmati@kgut.ac.ir.
Afzali D; Department of Environment, Institute of Science and High Technology and Environmental Sciences, Kerman, Iran.
Modiri S; Department of Chemical Engineering, Graduate University of Advanced Technology, Kerman, Iran.

Mater Sci Eng C Mater Biol Appl ; 105: 110010, 2019 Dec.

Article em En | MEDLINE | ID: mdl-31546426

Assuntos

Antineoplásicos/farmacologia; Portadores de Fármacos/química; Liberação Controlada de Fármacos; Mercaptopurina/farmacologia; Simulação de Dinâmica Molecular; Poliésteres/química; Adsorção; Polietilenoglicóis/química; Polimerização; Solubilidade

Palavras-chave

6-Mercaptopurine; Absorption; Molecular dynamics simulation; Polymer carrier; Release

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poliésteres / Portadores de Fármacos / Simulação de Dinâmica Molecular / Liberação Controlada de Fármacos / Mercaptopurina / Antineoplásicos Idioma: En Revista: Mater Sci Eng C Mater Biol Appl Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Irã

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