Six months stability investigation of sufentanil and ropivacaine/levobupivacaine admixtures in plastic containers by LC-UV.
J Pharm Biomed Anal
; 190: 113541, 2020 Oct 25.
Article
em En
| MEDLINE
| ID: mdl-32835913
ABSTRACT
The stability of sufentanil-ropivacaine and sufentanil-levobupivacaine solutions was evaluated during 6 months while stored at 4 °C. Containers for sufentanil-ropivacaine were syringe (made of polypropylene (PP)) and cassette (inside bag of polyvinylchloride) and for sufentanil-levobupivacaine syringe (PP) and infusion bag (inner layer of PP). A liquid chromatographic (LC) method was validated and allowed the measurement of the three analytes. Both solutions were found to be stable under the examined conditions with contents that remained close to 100 %.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Bupivacaína
/
Sufentanil
Tipo de estudo:
Clinical_trials
Idioma:
En
Revista:
J Pharm Biomed Anal
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Bélgica