Effect of streptozotocin diabetes on gingivitis in plaque-susceptible rats.
J Dent Res
; 65(1): 49-52, 1986 Jan.
Article
em En
| MEDLINE
| ID: mdl-3455698
ABSTRACT
The periodontal pocket probing depths of mandibular incisors of plaque-susceptible (Sus) rats, which spontaneously exhibit gingivitis with accumulation of plaque, were increased 20 days after injection of streptozotocin (70 mg/kg, i.v.). The accumulated plaque weights were also increased in Sus rats with streptozotocin diabetes, and a positive correlation was found between the plaque weights and the pocket depths. Histological findings showed that this inflammatory reaction in gingival tissue was higher and more extensive in diabetic Sus rats than in control Sus rats. These findings suggest that the accumulated plaque is the important factor for the severe breakdown of gingival tissue in this experimental model.
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Base de dados:
MEDLINE
Assunto principal:
Placa Dentária
/
Diabetes Mellitus Experimental
/
Gengivite
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
J Dent Res
Ano de publicação:
1986
Tipo de documento:
Article