Characterization of a new intra-H-2 recombinant separation of the Ir-RE and Ir-GLT genes.
J Exp Med
; 140(3): 859-64, 1974 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-4412395
ABSTRACT
This report characterizes the intra-H-2 crossover in the D2.GD mouse strain. Recombination occurred within the I region between the immune response (Ir) gene controlling immune responsiveness to ragweed extract (RE). Ir-RE, and the Ir gene governing responsiveness to the random linear terpolymers of glutamic acid and lysine with either tyrosine or pheylalanine (Ir-GLT and Ir-GLphi). The Ir-RE gene was tentatively located in the Ir-1A subregion and the Ir-GLT and Ir-GLphi gene(s) tentatively placed in the Ir-1B subregion. The importance of this recombinant strain to further studies on the fine structure of the I region is discussed.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Recombinação Genética
/
Mapeamento Cromossômico
/
Genes
/
Isoantígenos
Limite:
Animals
Idioma:
En
Revista:
J Exp Med
Ano de publicação:
1974
Tipo de documento:
Article