Does Opuntia ficus-indica Juice Supplementation Improve Biochemical and Cardiovascular Response to a 6-Minute Walk Test in Type 2 Diabetic Patients?

Background and objectives: The purpose of this study was to evaluate the effect of Opuntia ficus-indica juice (OFIJ) on performance and biochemical and physiological responses to a 6 min walking test (6MWT) in diabetic patients. Materials and Methods: Twenty diabetic patients performed a 6MWT at 07:00 h. During each test session, they were asked to drink 70 mL/day of natural OFIJ or placebo (PLA) for 4 days. Results: the results showed that cardiovascular parameters increased significantly after the 6MWT under both conditions. While, cortisol, HbA1c, cholesterol total (CT), triglycerides (TG), as well as low-density lipoprotein (LDL) were not modified between without and with supplementation. Likewise, no significant variation in performance was observed for PLA and OFIJ (p > 0.05). The cardiovascular parameters (heart rate max (HRmax), diastolic blood pressure (DBP), and systolic blood pressure (SBP)), lipid profile (CT, TG, LDL, and high-density lipoprotein HDL), hormonal parameters (insulin and glucagon), HbA1c and lactate ([La]) did not present any significant modification either between PLA or OFIJ (p > 0.05). Muscle-damage markers (creatine kinase (CK) and lactate dehydrogenase (LDH)], cortisol, and liver parameters (i.e., oxidative stress marker, γGT, and total bilirubin) as well as glucose (GLC) were affected by supplementation (p < 0.05) before and after the 6MWT, but this change was significant only for OFIJ (p < 0.05). Conclusion: OFIJ had an antioxidant capacity, improved performance of the 6MWT, and reduced muscle-damage markers and glucose level in type 2 diabetic patients.

Physiological Responses During Female Judo Combats: Impact of Combat Area Size and Effort to Pause Ratio Variations.

ABSTRACT: Ouergui, I, Kamzi, S, Houcine, N, Abedelmalek, S, Bouassida, A, Bouhlel, E, and Franchini, E. Physiological responses during female judo combats: impact of combat area size and effort to pause ratio variations. J Strength Cond Res 35(7): 1987-1991, 2021-This study investigated the effect of area size (4 × 4, 6 × 6, and 8 × 8 m) and effort-pause ratio (free combat, 2:1 and 3:1) on the physiological and perceptive responses during female judo combats. Twelve female judo athletes (mean ± SD: age: 17.1 ± 0.4 years; height: 160 ± 7 cm; body mass: 59.8 ± 11.5 kg; body fat: 25.7 ± 5.5%; and judo experience: 8.4 ± 0.5 years) volunteered to perform nine 4-minute randoris randomly determined. Blood lactate [La] before and after combats, heart rate before combat (HRpre), mean HR (HRmean), peak HR (HRpeak), and rating of perceived exertion (RPE) immediately after the combats were assessed for each condition. Results showed that [La] pre and HR values did not differ according to time structure and area sizes (p > 0.05). However, [La] post was higher on free randori compared with 3:1 ratio (p = 0.006) and in the 4 × 4-m area compared with 6 × 6-m (p < 0.001) and 8 × 8-m (p = 0.036) areas. Moreover, RPE was higher in the 4 × 4 m compared with 8 × 8 m (p = 0.038). In conclusion, combining time structure and area sizes may alter physiological and perceptual responses during female judo randori. Moreover, combat-based exercises may be effective in preparing athletes to cope with physiological and technical demands of the combat by stressing properly the energy systems solicited during official competitions.

Physiological Responses and Time-Motion Analysis of Kickboxing: Differences Between Full Contact, Light Contact, and Point Fighting Contests.

ABSTRACT: Ouergui, I, Benyoussef, A, Houcine, N, Abedelmalek, S, Franchini, E, Gmada, N, Bouhlel, E, and Bouassida, A. Physiological responses and time-motion analysis of kickboxing: differences between full contact, light contact, and point fighting contests. J Strength Cond Res 35(9): 2558-2563, 2021-This study investigated the physiological responses and time structure of kickboxing styles (full contact, light contact, and point fighting). Blood lactate [La] before and after combats, mean heart rate (HRmean), percentage of time spent in HR zones, and rating of perceived exertion were assessed. Time spent in high-intensity activities (HIAs), low-intensity activities (LIAs), and referee pauses (P) were recorded according to rounds (R) and kickboxing styles. [La] increased statistically significant after kickboxing combats (p < 0.001) and was higher after light contact compared with point fighting (p = 0.029). HRmean did not differ between kickboxing specialties (p = 0.200). However, more time was spent on HR zones 4 and 5 (Z4: 80-90% and Z5: 90-100% HRmax) than in other zones (all p < 0.001). Rating of perceived exertion scores were higher after light and full contact combats compared with point fighting (p = 0.007 and 0.093, respectively). High-intensity activities, LIAs, and pauses did not statistically differ across rounds (p > 0.05). Moreover, HIA values were lower than LIA (all p < 0.001), and HIA and LIA were higher than pause for all rounds and styles (all p < 0.001). Full contact elicited higher HIA compared with point fighting (p = 0.003, 0.001, and 0.002 for round 1, 2, and 3, respectively). Coaches and strength and conditioning professionals should emphasize anaerobic and muscle power development for all disciplines, especially for full and light contact and maximal aerobic power enhancement by targeting specific HR zones. Moreover, training regimen may include high-intensity interval training to mimic these sports' specificity using the effort-pause ratios according to different kickboxing sports.

Does red orange juice supplementation has a protective effect on performance, cardiovascular parameters, muscle damage and oxidative stress markers following the Yo-Yo Intermittent Recovery Test Level-1 under polluted air?

This study aimed to investigate the effect of red orange juice supplementation (ROJS) on performance, cardiovascular parameters, muscle damage and oxidative stress markers of athletes following exercise under polluted air. Eleven soccer players performed a Yo-Yo Intermittent Recovery Test Level-1 in polluted area (PA) and non-polluted area (NPA). Participants are invited to drink 500 ml of red orange or placebo (PLA) juice 2.5 h before the test. Blood samples were collected at rest and 3 min after each session to assess creatine kinase (CK), lactate dehydrogenase, malondialdehyde (MDA) and total antioxidant status. Our results showed that, VO2max, heart rate and systolic blood pressure post-exercise were significantly altered by pollution with both supplements, but the damage was lowered more with ROJS than PLA. Concerning muscle damage and oxidative stress markers, orange juice supplementation blunted the effect of pollution on CK levels post-exercise (p > 0.05) and decreases significantly (p < 0.05) the MDA levels post-exercise in PA and NPA compared to PLA supplementation. In conclusion, ROJS seemed to be an appropriate strategy to reduce the risk of exposure to pollution especially on muscle damage and oxidative stress markers.

Investigating the association between the lunar cycle and sleep, physiological, cognitive, and physical performance in children with Down syndrome.

BACKGROUND: Children with Down syndrome (DS) offer a compelling context within the fieldof human biology for examining potential lunar influences. While the exact mechanisms governing lunar effects are still under investigation, a growing body of scientific inquiry suggests possible connections between lunar phases and physiological, physical, and cognitive parameters. This investigation holds promise for uncovering the intricate interplay between lunar cycles (LCs) and the unique biology of children with DS. This study investigated the potential influence of the LC on physiological, physical, and cognitive parameters in children with DS, focusing on sleep patterns, physical performance, and cognitive abilities. MATERIALS AND METHODS: Seventeen children with DS participated in this study. Sleep data, physical performance metrics, and cognitive test results were collected throughout the LC, including the new moon (NM), first quarter, full moon (FM), and third quarter. Statistical analyses were conducted to assess the differences in these parameters across lunar phases. RESULTS: Significant differences were observed in sleep patterns, with reduced total sleep time (P < 0.01) and sleep efficiency (P < 0.001) during the FM phase. Heart rates (HRs) before (P < 0.001) and after (P < 0.01) exercise also displayed pronounced changes during LC. Additionally, the reaction time (RT) exhibited a significant difference (P < 0.01) across the lunar phases. However, physical performance metrics, including squat jump (SJ), sprint, and 6-minute walk distance (6MWD), did not show significant variations. CONCLUSION: This study suggests that LC may have a moderating effect on sleep patterns, HR, and cognitive performance in children with DS. These findings have practical implications for caregivers and educators and highlight the importance of considering lunar-associated variations in planning schedules and interventions for children with DS.

Effect of time of day and partial sleep deprivation on plasma concentrations of IL-6 during a short-term maximal performance.

The present study was designed to evaluate the effect of time of day and partial sleep deprivation (PSD) on short-term maximal performance and level of interleukin-6 (IL-6) in trained subjects. In a randomized order, 12 football players were asked to perform a 30-s Wingate test during which we measured the peak (PP) and mean (MP) powers. Measurements were performed at 0800 and 1800 hours, after two nocturnal regimens: (1) a reference normal sleep night (RN) and (2) 4 h of PSD caused by an early awakening. Plasma IL-6 concentrations were measured before (P1), immediately after (P2), and 60 min after the exercise (P3). PP and MP improved significantly from the morning to the afternoon after RN (P < 0.05) and from the afternoon to the morning after PSD (P < 0.05). Compared to RN, PP and MP were not affected by PSD the following morning. However, there was a significant decrease in PP and MP (P < 0.001) after the PSD at 1800 hours. In all conditions, IL-6 and resting core temperature were significantly higher (P < 0.05) in the afternoon than in the morning. In all sessions, IL-6 levels increased significantly from P1 to P2 (P < 0.01) and remained elevated in the afternoon during the recovery period after PSD (P < 0.05). However, no significant difference was observed in IL-6 between P1 and P3 during RN and PSD at 0800 hours. In conclusion, a short-term high-intensity exercise may increase the IL-6 concentrations in the morning and the afternoon. Moreover, IL-6 remained elevated during the recovery period in the afternoon after the PSD at the end of the night.

Effects of Ramadan fasting on the diurnal variations of physical and cognitive performances at rest and after exercise in professional football players.

Introduction: Ramadan fasting (RF) is characterized by daily abstinence from food and fluid intake from dawn to sunset. The understanding of the Ramadan effects on the diurnal variations of athletic and cognitive performance is crucial for practitioners, coach and researchers to prepare sport events and optimize performance. The aim of the present study was to reveal the effects of RF on the diurnal variation of physical and cognitive performances at rest and after exercise. Method: In a randomized order, 11 male football players (age: 19.27 ± 0.9; height: 1.79 ± 0.04 cm; body mass: 70.49 ± 3.97 kg; BMI: 21.81 ± 1.59 kg/m2) completed a 30-s Wingate test [i.e., mean (MP) and peak powers (PP)] at 07:00, 17:00, and 21:00 h on five occasions: 1 week before Ramadan (BR); the second (R2); the third (R3); the fourth (R4) week of Ramadan; and 2 weeks after Ramadan (AR), with an in-between recovery period of ≥72 h. Simple (SRT) and choice (CRT) reaction times, mental rotation test (MRT) and selective attention (SA) test were measured before and after Wingate test. Rating of perceived exertion (RPE), body composition, dietary intake, profile of mood states (POMS) and Pittsburgh Sleep Quality Index (PSQI) were assessed over the five periods. Results: Compared to BR, RF decreased MP at 17:00 h (p < 0.05, d = 1.18; p < 0.001, d = 2.21, respectively) and PP at 17:00 h (p < 0.05, d = 1.14; p < 0.001, d = 1.77, respectively) and 21:00 h (p < 0.01, d = 1.30; p < 0.001, d = 2.05, respectively) at R3 and R4. SRT (p < 0.001,d = 1.15; d = 1.32, respectively), number of correct answers (MRTE; p < 0.05, d = 1.27; d = 1.38, respectively) and SA (p < 0.01, d = 1.32; d = 1.64, respectively) increased during R2 and R3 in the evening before exercise compared to BR. Short term maximal exercise enhanced SRT (p < 0.01, d = 1.15; p < 0.001, d = 1.35, respectively), MRTE (p < 0.001, d = 2.01; d = 2.75 respectively) and SA (p < 0.05, d = 0.68; d = 1.18, respectively) during R2 and R3 in the evening. In comparison to BR, sleep latency and sleep duration increased during R3 (p < 0.001, d = 1.29; d = 1.74, respectively) and R4 (p < 0.001, d = 1.78; d = 2.19, respectively) and sleep quality increased in R2, R3 and R4 (p < 0.01, d = 1.60; p < 0.001, d = 1.93; d = 2.03, respectively). Conclusion: During RF, anaerobic and cognitive performances were unaffected in the morning but were impaired in the afternoon and evening. Short-term maximal exercise mitigates the negative effects of fasting on cognitive performance. Maximal exercise could thus partially counteract the effect of fasting on cognitive function.

Exergaming During Ramadan Intermittent Fasting Improve Body Composition as Well as Physiological and Psychological Responses to Physical Exercise in Adolescents With Obesity.

The effects of exergaming on biochemical responses has been investigated; however, no data is available for this effect during Ramadan intermittent fasting (RIF). RIF is a daily fasting characterized by abstaining from eating and drinking from sunrise to sunset for 29-30 days. The purpose of this study was to investigate the effect of exergaming during RIF on body composition, physical performance and hematological parameters in overweight and adolescents with obesity. Twenty-four adolescents with obesity were divided into two groups [control group (CG), n = 12, or cooperative sport exergaming group (EG), n = 12: 45 min per session during five days per week)]. Participants completed a 6-min walking test (6MWT), a squat jump test and a 10 and a 30m sprint tests in four different occasions: before Ramadan (T0), the second week of Ramadan (T1), the fourth week of Ramadan (T2), and after Ramadan (T3). Blood pressure, rating of perceived exertion (RPE), body composition, central obesity index, dietary intake and profile of mood states (POMS) were, also, assessed over the four periods. The results showed that body weight, body mass index and body fat percentage were significantly lower at T2 compared to T0 and T1 in the EG. After RIF, body composition returned to the values recorded before RIF. The POMS score was significantly lower during T2 compared to T0, T1 and T3 in the EG. The vertical jump and the 6MWT distance were significantly higher (i) at T2 compared to T0, T1 and T3 in the EG and (ii) in EG compared to CG at T2. RPE was significantly lower (i) at T2 compared to T0, T1 and T3 in the EG and (ii) in EG compared to CG at T2. Blood pressure was lower during T2 compared to the other periods in EG. The EG experienced significant decreases in total cholesterol and triglycerides during T2. However, no significant changes between groups and periods was reported for all the other parameters. In conclusion, exergaming during RIF has a positive effect on body composition and physiological and psychological responses in adolescents with obesity.

The effect of time of day and high intensity exercise on cognitive performances of elite adolescent karate athletes.

To explore the effect of time of day (TOD) on several components of cognitive performance prior and post to a physically exhaustive task in a sample of adolescent elite athletes. In a counterbalanced and randomized order, fourteen highly trained male karate athletes (17 ± 0.96 years; 1.75 ± 0.07 m; 68.0 ± 9.50 kg; BMI 22.15 ± 0.54 kg.m-2) completed two test sessions at 09h00 and 16h00. Cognitive performance was evaluated before and after the karate specific test (KST). During each session, participants completed the profile of mood state (POMS), simple (SRT) and choice (CRT) reaction times, comparison test (COMT), mental rotation test (MRT), egocentric distance estimation (DE), and the rating of perceived exertion (RPE). KST was not TOD dependent (p > .05, d = 0.33). RPE scores were higher in the afternoon compared to the morning (p < .05, d = 0.68). Before the KST, SRT (p < .01, d = 0.69), CRT (p < .01, d = 0.47), COMT (p < .01, d = 0.62) and MRT (p < .001, d = 0.65) were better in the afternoon than in the morning. However, DE was not affected by the TOD (P > .05). KST improved SRT (p < .01, d = 0.078), CRT (p < .001, d = 0.72), COMT (p < .001, d = 1.31) and MRT (p < .001, d = 0.80) performances only in the morning. Cognitive performances are TOD dependent with higher performances realized in the afternoon. Performing a high intensity exercise in the morning, but not in the afternoon, enhanced several aspects of cognitive performances. The current results indicate that an intensive warm-up could be beneficial when a morning competition requires high cognitive readiness.

Physical Activity, Sleep Patterns and Diet Habits as Well as the Prevalence of Obesity among Adolescents: A Cross Sectional Study from Ha'il City in Saudi Arabia.

Obesity is expected to increase in the Kingdom of Saudi Arabia (KSA). Therefore, the objective of this study was to determine the physical activity, sleep patterns and diet habits as well as the prevalence of obesity among adolescents from Ha'il City. A cross-sectional study was conducted with 1598 adolescent students (663 males and 935 females) aged 12−15 years who were randomly selected from different schools in Ha'il. Body mass index (BMI) was used to classify participants as underweight, normal weight, overweight and obese (class and class II). Moreover, physical activity, sleep patterns and diet habits were recorded. The prevalence of obesity was 52.1%. Obesity is significantly more prevalent in females compared to males (62.9% vs. 36.59%, p < 0.001). Moreover, students in the third grade are the most obese in comparison with the first and the second educational level (p < 0.001). Additionally, students aged 15 years old are the most obese compared to 12 years, 13 years and 14 years (p < 0.001). Additionally, the results showed that students who suffer from obesity eat food when they feel higher stress and tension scores and that they do not eat their meals regularly. Additionally, 79% of those who eat fried food daily are obese. It was reported that 61.1% of students in this study were physically inactive. Furthermore, 58.4% of students have a higher proportion of insufficient sleeping duration (>7 h per night) (p < 0.001). This increased rate of obesity is higher in females compared to males and it was related to inactivity as well as perturbed sleep and eating habits. Therefore, we recommend an obesity prevention program including health education in Ha'il City, KSA.

Listening to Music and Playing Activities during Recreation between Lessons Regenerate Children's Cognitive Performance at Different Times of Day.

The interruption of learning processes by breaks filled with diverse activities is common in everyday life. The purpose of this study was to investigate the effects of the time of day (TOD) of playing with or without music during recess on cognitive performance regeneration among students aged between 11 and 12. Twenty-seven volunteer children (aged 12 ± 0.6 years) completed four trials at 09h45, 10h15, 14h45, and 15h15. Each test session was separated by recreation between classroom lessons with different conditions: music only (MSC), playing only (PAY), music and playing (MSC-PAY), and without music and playing (NON). During each session, oral temperature, reaction time (RT), and constant attention (CA) were measured. For all parameters, the ANOVA revealed a significant effect of the type of activity. However, no significant effect of the TOD and no significant interaction of type of activity × TOD were reported. The Bonferroni post hoc test revealed that Δ-core temperature was significantly higher during PAY and MSC-PAY compared to NON (p < 0.05). Δ-attention was higher during MSC, PAY, and MSC-PAY compared to NON (p < 0.001). Δ-attention was lower during MSC (p < 0.05), PAY (p < 0.05), and MSC-PAY (p < 0.01) compared to NON. Therefore, playing, listening to music, and playing while listening to music at recess improve the child's ability to regenerate cognitive performance regardless of the TOD.

Listening to motivational music during warming-up attenuates the negative effects of partial sleep deprivation on cognitive and short-term maximal performance: Effect of time of day.

This study assessed the effect of time of day (TOD) and listening to music during warm-up on cognitive and physical performances after partial sleep deprivation (PSD) and normal sleep nights (NSN). In a randomized order, twelve male physical education students [mean (SD) age 20.3 ± 2.0 y; BMI 22.90 ± 3.57 kg/m2)] completed a 30-s Wingate test (i.e., mean (MP) and peak powers (PP)), simple (SRT) and choice reaction times (CRT), a mental rotation test (MRT) and a selective attention test. Measurements were performed at 07:00 h and 17:00 h after a NSN and PSD with and without music, with an in-between recovery period of ≥72. Salivary cortisol was measured before and immediately after the Wingate test. Compared to NSN, the results showed that PSD decreased PP (p < .05, d = 0.86) and MP (p < .01, d = 0.86) in the afternoon. However, compared to NSN, listening to music during the warm up after PSD enhanced PP (p < .01, d = 1.40) and MP (p < .05, d = 0.82) in the morning and PP (p < .05, d = 0.78) in the afternoon. Moreover, listening to music lowered post-exercise cortisol in the morning both after NSN (p < .05, d = 0.79) and PSD (p < .05, d = 0.11). After PSD, music reduced the negative mood states (p < .01, d = 0.94), the SRT (p < .05, d = 0.79) and the CRT (p < .05, d = 0.49) in the afternoon. These findings suggest that listening to music during warm-up (i) enhances cognitive and short-term all out performances after NSN and PSD and (ii) partially counteracts sleep-loss-induced degradation of physical and cognitive performances at both TODs.

The effect of Opuntia ficus-indica juice supplementation on oxidative stress, cardiovascular parameters, and biochemical markers following yo-yo Intermittent recovery test.

The aim of the study was to investigate the effect of a flavonoid-rich fresh fruit juice on cardiovascular, oxidative stress, and biochemical parameters during the yo-yo intermittent recovery test (YYIRT). Twenty-two healthy males subjects participated in this study divided into two groups: An experimental group (EG: n = 11) who consumed the antioxidant supplement and a control group (CG: n = 11). All participants performed two test sessions at 07:00 hr before and after 2 weeks of supplementation with Opuntia ficus-indica juice. Blood samples were taken before (P1) and immediately (P2) after the YYIRT. Our results showed that following the 2,2-diphenyl-1- picrylhydrazyl (DPPH ●) test, the Opuntia ficus-indica juice has an antioxidant capacity for capturing free radicals (p < .05) and reducing oxidative stress related to exercise. Concerning biochemical and cardiovascular parameters, our results showed a significant increase on total cholesterol (TC) (p < .01), triglycerides (TG) (p < .05), high-density lipoprotein (HDL) (p < .01), low-density lipoprotein (LDL) (p < .01), creatine kinase (CK) (p < .01), lactate deshydrogenase (LDH) (p < .01), glucose (GLC) (p < .01), systolic (SBP), and diastolic blood pressure (DBP) (p < .01) immediately after exercise. However, TC (p < .05), TG (p < .05) and LDL (p < .05), the maximal heart rate (HRmax), the CK (p < .05), and LDH (p < .01) as well as the malondialdehyde (MDA) (p < .01) demonstrated a significant decrease after supplementation of Opuntia ficus-indica juice before and immediately after YYIRT. However, no significant effect on HDL (p > .05), GLC (p > .05) levels nor the SBP and DBP (p > .05) was observed after supplementation with Opuntia ficus-indica juice. The supplementation leads to an improvement on YYIRT performance (The total distance covered during the YYIRT,VO 2max, VMA) and the rating of perceived exertion (RPE). Opuntia ficus-indica juice has a potent antioxidant activity that reduces total and LDL-cholesterol with only a moderate lowering of HDL-cholesterol and oxidative stress. Moreover, supplementation decreases muscle damage caused by the endurance exercise.

The effect of air pollution on diurnal variation of performance in anaerobic tests, cardiovascular and hematological parameters, and blood gases on soccer players following the Yo-Yo Intermittent Recovery Test Level-1.

This study aimed to investigate the effect of air pollution on diurnal variation of performance in anaerobic tests, cardiovascular and hematological parameters, and blood gases on soccer players following the Yo-Yo Intermittent Recovery Test Level-1 (YYIRT1). In a randomized order, 11 healthy soccer players (mean age: 21.8 [range: 20-24] years; height: 178.00 [range: 1.64-1.83] cm; body mass index [BMI]: 23.57 [range: 20.45-28.03] kg.m-2) performed a YYIRT1 at two different times of day (TOD) (08:00 h and 18:00 h) in two areas (i.e. polluted (PA) and non-polluted (NPA)) with a recovery period of ≥ 72 h in between, to determine the maximal oxygen uptake (VO2max). In each test session: resting oral temperature is measured, anaerobic performances (pre- and post-YYIRT1) were performed, cardiovascular parameters and blood samples were collected at: rest, 3 min and 60 min after the YYIRT1, to assess blood gases and hematological parameters. Our results showed that, agility performance, VO2max, red blood cells (RBC), hemoglobin (Hb), pH, and bicarbonate levels (HCO3-) decrease significantly (p < 0.001) following the YYIRT1 in PA compared to NPA. Likewise, the heart rate (HR), systolic blood pressure (SBP), platelets (PLT), white blood cells (WBC), neutrophiles (NEUT), lymphocytes (LYM), and partial pressure of CO2 levels (PvCO2) were significantly higher (p < 0.001) in PA. This effect was slightly accentuated at 18:00 h for some parameters (i.e. Agility, HCO3-, HR, PvCO2, RBC, SBP). However, performances of sprint and Sargent jump test (SJT), oral temperature, rate of perceived exertion scales (RPE), partial pressure of O2 (PvO2), diastolic blood pressure (DBP), and monocytes (MON) were not affected by pollution (p > 0.05). In conclusion, pollution seems to be critical for health stability and performance in response to YYIRT1 especially in the evening and the winter season. Therefore, coaches and athletes should draw attention to the potential importance of land use planning in their training sessions and competitions in the morning in polluted area to minimize the risk of pollution exposure.

Caloric Restriction Effect on Proinflammatory Cytokines, Growth Hormone, and Steroid Hormone Concentrations during Exercise in Judokas.

The aim of this study was to evaluate the effect of caloric restriction on the immune and hormonal responses during exercise in judo athletes. In a randomised order, 11 male judokas (age: 20.45 ± 0.51; height: 1.71 ± 0.3 m; and body weight: 75.9 ± 3.1 kg) participate in this study during a period of weight maintenance (baseline) and after 7 days of caloric restriction (CR). All subjects performed the Special Judo Fitness Test (SJFT) during the two conditions. Values for nutrient intakes were obtained from a 7 d food record kept during a period of weight maintenance and after a 7-day food restriction (-5~6 MJ/day). Our results showed that CR resulted in significant decreases in body weight (P < 0.05) and performance (P < 0.05). However, heart rate and SJFT index (P < 0.05) increase significantly during CR in comparison to baseline. Moreover, exercise leads to a significant increase in testosterone, cortisol, growth hormone (GH), leukocytes, neutrophils, TNF-α, and IL-6, in both CR and baseline conditions. Compared to baseline, TNF-α and IL-6 were significantly higher during CR condition (P < 0.05). Additionally, CR leads to an increase in cortisol and GH (P < 0.05) and a decrease in testosterone concentrations (P < 0.05).

The effects of caffeine ingestion on the reaction time and short-term maximal performance after 36 h of sleep deprivation.

The aim of the present study was to investigate the effects of caffeine ingestion on cognitive and physical performances after 36h of sleep deprivation. In randomized order, thirteen healthy male physical education students (age: 21.1±1.1years, body mass: 77.1±7.2kg, height: 1.77±0.06m) completed four test sessions at 18:00h: after placebo or 5mg·kg(-1) of caffeine ingestion during a baseline night (RN) (bed time: from 22:30h to 07:00h) or a night of 36h of sleep deprivation (TSD). During each test session, participants performed the squat jump (SJ), the reaction time, and the 30-s Wingate tests (i.e., for the measurement of the peak (PP) and mean (MP) powers and the fatigue index (FI)). The results showed that PP and MP decreased and FI increased during the TSD compared to RN in the placebo condition (p<0.001). The caffeine ingestion improved PP after TSD compared to RN (p<0.001). SJ decreased significantly after the TSD compared to RN after both placebo and caffeine ingestions (p<0.001). However, SJ increased significantly after caffeine ingestion during RN and TSD (p<0.001). The reaction time increased significantly after TSD compared to RN (p<0.001). However, the reaction time decreased significantly after the caffeine ingestion only during the TSD (p<0.001). Therefore, caffeine is an effective strategy to counteract the effect of 36h of sleep loss on physical and cognitive performances.

Effects of partial sleep deprivation on proinflammatory cytokines, growth hormone, and steroid hormone concentrations during repeated brief sprint interval exercise.

The purpose of this study was to evaluate the effects of partial sleep deprivation (PSD) on circulating concentrations of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) in relation to the secretory profiles of growth hormone (GH), cortisol, and testosterone during a repeated brief sprint interval exercise. Thirty healthy football players (mean age: 21.1 [range: 18-24] years; body mass index [BMI]: 22.6 [range: 18.47-24.46] Kg/m(2)) completed two test sessions at 08:00 h, one scheduled after a baseline night (bedtime: from 22:30 to 07:00 h) and the other after a PSD night caused by an early awakening (bedtime: from 22:30 to 03:00 h). During each session, participants performed 4 × 250-m run on a treadmill at a constant intensity of 80% of the personal maximal speed with a 3-min recovery in between. Tests session were performed at 08:00 h. Blood samples were collected before, immediately after the first and the fourth 250-m run, and 60 min after the exercise. The results showed that cortisol concentrations were not affected by the PSD. However, GH and testosterone concentrations were higher (p < .05) 60 min after the exercise during PSD in comparison with baseline. Likewise, plasma concentrations of IL-6 and TNF-α were higher (p < .05) after PSD during the exercise (i.e., the first and the fourth run) and remained elevated during the recovery period (i.e., 60 min after the exercise). In conclusion, these results showed that sleep restriction increases the proinflammatory cytokine, GH, and testosterone concentrations after physical exercise but did not affect the cortisol responses.

Effects of morning caffeine' ingestion on mood States, simple reaction time, and short-term maximal performance on elite judoists.

PURPOSE: The purpose of the present study was to evaluate the ergogenic effect of caffeine ingestion on mood state, simple reaction time, and muscle power during the Wingate test recorded in the morning on elite Judoists. METHODS: TWELVE ELITE JUDOISTS (AGE: 21.08 ± 1.16 years, body mass: 83.75 ± 20.2 kg, height: 1.76 ±6.57 m) participated in this study. Mood states, simple reaction time, and muscle power during the Wingate test were measured during two test sessions at 07:00 h and after placebo or caffeine ingestion (i.e. 5 mg/kg). Plasma concentrations of caffeine were measured before (T0) and 1-h after caffeine' ingestion (T1) and after the Wingate test (T3). RESULTS: Our results revealed an increase of the anxiety and the vigor (P<0.01), a reduction of the simple reaction time (P<0.001) and an improvement of the peak and mean powers during the Wingate test. However, the fatigue index during this test was unaffected by the caffeine ingestion. In addition, plasma concentration of caffeine was significantly higher at T1 in comparison with T0. CONCLUSIONS: In conclusion, the results of this study suggest that morning caffeine ingestion has ergogenic properties with the potential to benefit performance, increase anxiety and vigor, and decrease the simple reaction time.

Effect of Acute Maximal Exercise on Circulating Levels of Interleukin-12 during Ramadan Fasting.

PURPOSE: The purpose of this study was to examine the effects of Ramadan fasting on circulating levels of interleukin-12 (IL-12) after a brief maximal exercise. METHODS: NINE SUBJECTS PERFORMED A WINGATE TEST ON THREE DIFFERENT OCCASIONS: (i) the first week of Ramadan (1WR), (ii) the fourth week of Ramadan (4WR), and (iii) three weeks after Ramadan (AR). Blood samples were taken before, immediately and 60 min after the exercise. Plasma concentrations of IL-12 were measured using enzyme-linked immunosorbent assay. Variance analysis revealed no significant effect of Ramadan on P(peak) and P(mean) during the three testing periods. RESULTS: Considering the effect of Ramadan on plasma concentrations of IL-12, analysis of the variance revealed a significant Ramadan effect (F((2,) (16))=66.27; P < 0.001) as well as a significant time effect (F((2,) (16))= 120.66; P < 0.001). However, no significant (Ramadan × time) of test interaction (F((4,) (32))=2.40; P>0.05). For all measures, IL-12 levels were lower during 1WR and 4WR in comparison with AR (P < 0.05). Considering the exercise effects, IL-12 levels measured immediately after the exercise were significantly higher than those measured before and at 60 minutes after the exercise (P < 0.001). CONCLUSIONS: These results suggest that an acute intense exercise-induced IL-12 response is modified by daytime fasting and modifications in sleep schedule during Ramadan.