Búsqueda | Biblioteca Virtual en Salud Odontología. Uruguay

1.

Antenatal Ureaplasma Infection Causes Colonic Mucus Barrier Defects: Implications for Intestinal Pathologies.

van Gorp, Charlotte; de Lange, Ilse H; Hütten, Matthias C; López-Iglesias, Carmen; Massy, Kimberly R I; Kessels, Lilian; Knoops, Kèvin; Cuijpers, Iris; Sthijns, Mireille M J P E; Troost, Freddy J; van Gemert, Wim G; Spiller, Owen B; Birchenough, George M H; Zimmermann, Luc J I; Wolfs, Tim G A M.

Int J Mol Sci ; 25(7)2024 Apr 03.

Artículo en Inglés | MEDLINE | ID: mdl-38612809

2.

Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice.

Schroeder, Bjoern O; Birchenough, George M H; Pradhan, Meenakshi; Nyström, Elisabeth E L; Henricsson, Marcus; Hansson, Gunnar C; Bäckhed, Fredrik.

J Biol Chem ; 295(46): 15712-15726, 2020 11 13.

Artículo en Inglés | MEDLINE | ID: mdl-32900852

3.

Loss of Trefoil Factor 2 Sensitizes Rat Pups to Systemic Infection with the Neonatal Pathogen Escherichia coli K1.

McCarthy, Alex J; Birchenough, George M H; Taylor, Peter W.

Infect Immun ; 87(5)2019 03.

Artículo en Inglés | MEDLINE | ID: mdl-30833331

4.

Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16.

Bergström, Joakim H; Birchenough, George M H; Katona, Gergely; Schroeder, Bjoern O; Schütte, André; Ermund, Anna; Johansson, Malin E V; Hansson, Gunnar C.

Proc Natl Acad Sci U S A ; 113(48): 13833-13838, 2016 11 29.

Artículo en Inglés | MEDLINE | ID: mdl-27849619

5.

The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.

Pelaseyed, Thaher; Bergström, Joakim H; Gustafsson, Jenny K; Ermund, Anna; Birchenough, George M H; Schütte, André; van der Post, Sjoerd; Svensson, Frida; Rodríguez-Piñeiro, Ana M; Nyström, Elisabeth E L; Wising, Catharina; Johansson, Malin E V; Hansson, Gunnar C.

Immunol Rev ; 260(1): 8-20, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24942678

6.

Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli.

Birchenough, George M H; Johansson, Malin E V; Stabler, Richard A; Dalgakiran, Fatma; Hansson, Gunnar C; Wren, Brendan W; Luzio, J Paul; Taylor, Peter W.

Infect Immun ; 81(9): 3264-75, 2013 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-23798529

7.

Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection.

Birchenough, George M H; Schroeder, Bjoern O; Sharba, Sinan; Arike, Liisa; Recktenwald, Christian V; Puértolas-Balint, Fabiola; Subramani, Mahadevan V; Hansson, Karl T; Yilmaz, Bahtiyar; Lindén, Sara K; Bäckhed, Fredrik; Hansson, Gunnar C.

Cell Rep ; 42(2): 112084, 2023 02 28.

Artículo en Inglés | MEDLINE | ID: mdl-36753416

8.

Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation.

Song, Ran; McAlpine, William; Fond, Aaron M; Nair-Gill, Evan; Choi, Jin Huk; Nyström, Elisabeth E L; Arike, Liisa; Field, Sydney; Li, Xiaohong; SoRelle, Jeffrey A; Moresco, James J; Moresco, Eva Marie Y; Yates, John R; Azadi, Parastoo; Ni, Josephine; Birchenough, George M H; Beutler, Bruce; Turer, Emre E.

Nat Commun ; 14(1): 3652, 2023 06 20.

Artículo en Inglés | MEDLINE | ID: mdl-37339972

9.

Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer.

Sharpen, Jack D A; Dolan, Brendan; Nyström, Elisabeth E L; Birchenough, George M H; Arike, Liisa; Martinez-Abad, Beatriz; Johansson, Malin E V; Hansson, Gunnar C; Recktenwald, Christian V.

Nat Commun ; 13(1): 45, 2022 01 11.

Artículo en Inglés | MEDLINE | ID: mdl-35017479

10.

NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation.

van der Post, Sjoerd; Birchenough, George M H; Held, Jason M.

Cell Rep ; 35(1): 108949, 2021 04 06.

Artículo en Inglés | MEDLINE | ID: mdl-33826887

11.

An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function.

Nyström, Elisabeth E L; Martinez-Abad, Beatriz; Arike, Liisa; Birchenough, George M H; Nonnecke, Eric B; Castillo, Patricia A; Svensson, Frida; Bevins, Charles L; Hansson, Gunnar C; Johansson, Malin E V.

Science ; 372(6539)2021 04 16.

Artículo en Inglés | MEDLINE | ID: mdl-33859001

12.

The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function.

Volk, Joana K; Nyström, Elisabeth E L; van der Post, Sjoerd; Abad, Beatriz M; Schroeder, Bjoern O; Johansson, Åsa; Svensson, Frida; Jäverfelt, Sofia; Johansson, Malin E V; Hansson, Gunnar C; Birchenough, George M H.

J Exp Med ; 216(11): 2602-2618, 2019 11 04.

Artículo en Inglés | MEDLINE | ID: mdl-31420376

13.

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration.

Schroeder, Bjoern O; Birchenough, George M H; Ståhlman, Marcus; Arike, Liisa; Johansson, Malin E V; Hansson, Gunnar C; Bäckhed, Fredrik.

Cell Host Microbe ; 23(1): 27-40.e7, 2018 01 10.

Artículo en Inglés | MEDLINE | ID: mdl-29276171

14.

Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity.

Nyström, Elisabeth E L; Birchenough, George M H; van der Post, Sjoerd; Arike, Liisa; Gruber, Achim D; Hansson, Gunnar C; Johansson, Malin E V.

EBioMedicine ; 33: 134-143, 2018 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-29885864

15.

Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection.

Birchenough, George M H; Dalgakiran, Fatma; Witcomb, Luci A; Johansson, Malin E V; McCarthy, Alex J; Hansson, Gunnar C; Taylor, Peter W.

Sci Rep ; 7(1): 83, 2017 03 06.

Artículo en Inglés | MEDLINE | ID: mdl-28250440

16.

A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion.

Birchenough, George M H; Nyström, Elisabeth E L; Johansson, Malin E V; Hansson, Gunnar C.

Science ; 352(6293): 1535-42, 2016 Jun 24.

Artículo en Inglés | MEDLINE | ID: mdl-27339979

17.

Forming a mucus barrier along the colon.

Birchenough, George M H; Johansson, Malin E V.

Science ; 370(6515): 402-403, 2020 10 23.

Artículo en Inglés | MEDLINE | ID: mdl-33093095

18.

The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.

Erickson, Nancy A; Nyström, Elisabeth E L; Mundhenk, Lars; Arike, Liisa; Glauben, Rainer; Heimesaat, Markus M; Fischer, André; Bereswill, Stefan; Birchenough, George M H; Gruber, Achim D; Johansson, Malin E V.

PLoS One ; 10(7): e0131991, 2015.

Artículo en Inglés | MEDLINE | ID: mdl-26162072

19.

Non-invasive model of neuropathogenic Escherichia coli infection in the neonatal rat.

Dalgakiran, Fatma; Witcomb, Luci A; McCarthy, Alex J; Birchenough, George M H; Taylor, Peter W.

J Vis Exp ; (92): e52018, 2014 Oct 29.

Artículo en Inglés | MEDLINE | ID: mdl-25408299

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