1.
Anticancer Agents Med Chem
; 11(2): 222-32, 2011 Feb.
Artículo
en Inglés
| MEDLINE
| ID: mdl-21355841
RESUMEN
Texaphyrins, a class of tumor selective expanded porphyrins capable of coordinating large metals, have been found to act as redox mediators within biological systems. This review summarizes studies involving their experimental use in cancer chemotherapy. Mechanistic insights involving their presumed mode of action are also described, as well as certain structure activity relationships. Finally, newer texaphyrin-based applications associated with targeted drug delivery are presented.