RESUMEN
Neurological compression occurs in 10%-20% of patients who develop spinal metastases. In the last decade, the evolution of oncological diagnostic and medical techniques, the change from conventional external radiation to radiosurgery and the new surgical instruments have meant that the treatment of these patients must be indicated in a personalized manner and by consensus, multidisciplinary way, in specific commissions. Today, the biological state of the patient, the presence of mechanical instability, the neurological assessment and degree of epidural compression, as well as the best prognostic categorization of the tumor, are established as decision factors prior to the indication of surgical treatment, treatment that has passed from a cytoreductive concept to that of a spinal cord release from tumor in order to ensure safe radiosurgery.
RESUMEN
Neurological compression occurs in 10%-20% of patients who develop spinal metastases. In the last decade, the evolution of oncological diagnostic and medical techniques, the change from conventional external radiation to radiosurgery and the new surgical instruments have meant that the treatment of these patients must be indicated in a personalized manner and by consensus, multidisciplinary way, in specific commissions. Today, the biological state of the patient, the presence of mechanical instability, the neurological assessment and degree of epidural compression, as well as the best prognostic categorization of the tumor, are established as decision factors prior to the indication of surgical treatment, treatment that has passed from a cytoreductive concept to that of a spinal cord release from tumor in order to ensure safe radiosurgery.
RESUMEN
This paper will consider the influence of the temperature of autohydrolysis or hydrothermal process from Paulownia fortunei L. to obtain a valuable liquid phase and a suitable solid phase to produce pulp. The solid phase resulting of autohydrolysis was subjected to organosolv pulping process and formed paper sheets, analyzing the influence of operational variables (viz., ethanol concentration, temperature and pulping time) on the yield, viscosity, tensile index, burst index, tear index and brightness. Maximum glucose and xylose contents and minimum paper sheets characteristic loss have been obtained at 190 degrees C authohydrolysis temperature. Suitable characteristics of paper sheets and acceptable yield, viscosity and kappa number of pulp could be obtained by operating at 180 degrees C temperature, 30min pulping time and 20% ethanol concentration. Under those conditions sheets paper with 27.4% ISO brightness, 28.87Nm/g tensile index, 1.22kPam(2)/g burst index and 1.23kNm(2)/g tear index could be obtained.
Asunto(s)
Etanol/química , Magnoliopsida/química , Papel , Solventes/química , Madera/química , Calor , Hidrólisis , Madera/análisisRESUMEN
The influence of temperature in the hydrothermal treatment of sunflower stalks on the composition of the liquid fraction obtained was examined. The remaining solid fraction was subjected to ethanol pulping in order to obtain pulp that was used to produce paper sheets. The pulp was characterized in terms of yield, kappa index, viscosity, and cellulose, hemicellulose and lignin contents; and the paper sheets in terms of breaking length, stretch, burst index and tear index. Hydrothermal treatment of the raw material at 190 degrees C provided a liquid phase with maximal hemicellulose-derived oligomers and monosaccharide (glucose, xylose and arabinose) contents (26.9 and 4.2 g/L, respectively). Pulping the solid fraction obtained by hydrothermal treatment at 180 degrees C, with 70% ethanol at a liquid/solid ratio of 8:1 at 170 degrees C for 120 min provided pulp with properties on a par with those of soda pulp from the sunflower stalks, namely: 36.3% yield, 69.1% cellulose, 12.6% hemicellulose, 18.2% lignin and 551 ml/g viscosity. Also, paper sheets obtained from the ethanol pulp were similar in breaking length (3.8 km), stretch (1.23%), burst index (1.15 kN/g) and tear index (2.04 m Nm(2)/g) to those provided by soda pulp.
Asunto(s)
Etanol/química , Helianthus/química , Calor , Tallos de la Planta/química , Agua , PapelRESUMEN
La compresión neurológica se presenta entre el 10-20% de los pacientes que desarrollan una metástasis vertebral. En la última década, la evolución de las técnicas diagnósticas y médicas oncológicas, el cambio de la radiación convencional externa a la radiocirugía y los nuevos instrumentales quirúrgicos, han hecho que el tratamiento de estos pacientes deba de ser indicado de forma personalizada y en consenso, de forma multidisciplinar, en comisiones específicas.Hoy, el estado biológico del paciente, la presencia de inestabilidad mecánica, la valoración neurológica y el grado de compresión epidural, así como la mejor categorización pronóstica del tumor, se establecen como los factores de decisión previa a la indicación del tratamiento quirúrgico, tratamiento que ha pasado de un concepto «citorreductor» al de «separador» o «preparador» de la médula para asegurar una radiocirugía segura.(AU)
Neurological compression occurs in 10%-20% of patients who develop spinal metastases. In the last decade, the evolution of oncological diagnostic and medical techniques, the change from conventional external radiation to radiosurgery and the new surgical instruments have meant that the treatment of these patients must be indicated in a personalized manner and by consensus, multidisciplinary way, in specific commissions.Today, the biological state of the patient, the presence of mechanical instability, the neurological assessment and degree of epidural compression, as well as the best prognostic categorization of the tumor, are established as decision factors prior to the indication of surgical treatment, treatment that has passed from a cytoreductive concept to that of a spinal cord release from tumor in order to ensure safe radiosurgery.(AU)
Asunto(s)
Humanos , Masculino , Femenino , Metástasis de la Neoplasia , Columna Vertebral/cirugía , Calidad de Vida , Neoplasias de la Columna Vertebral/tratamiento farmacológico , Terapéutica/métodos , Traumatología , Procedimientos Ortopédicos , Ortopedia , NeoplasiasRESUMEN
La compresión neurológica se presenta entre el 10-20% de los pacientes que desarrollan una metástasis vertebral. En la última década, la evolución de las técnicas diagnósticas y médicas oncológicas, el cambio de la radiación convencional externa a la radiocirugía y los nuevos instrumentales quirúrgicos, han hecho que el tratamiento de estos pacientes deba de ser indicado de forma personalizada y en consenso, de forma multidisciplinar, en comisiones específicas.Hoy, el estado biológico del paciente, la presencia de inestabilidad mecánica, la valoración neurológica y el grado de compresión epidural, así como la mejor categorización pronóstica del tumor, se establecen como los factores de decisión previa a la indicación del tratamiento quirúrgico, tratamiento que ha pasado de un concepto «citorreductor» al de «separador» o «preparador» de la médula para asegurar una radiocirugía segura.(AU)
Neurological compression occurs in 10%-20% of patients who develop spinal metastases. In the last decade, the evolution of oncological diagnostic and medical techniques, the change from conventional external radiation to radiosurgery and the new surgical instruments have meant that the treatment of these patients must be indicated in a personalized manner and by consensus, multidisciplinary way, in specific commissions.Today, the biological state of the patient, the presence of mechanical instability, the neurological assessment and degree of epidural compression, as well as the best prognostic categorization of the tumor, are established as decision factors prior to the indication of surgical treatment, treatment that has passed from a cytoreductive concept to that of a spinal cord release from tumor in order to ensure safe radiosurgery.(AU)
Asunto(s)
Humanos , Masculino , Femenino , Metástasis de la Neoplasia , Columna Vertebral/cirugía , Calidad de Vida , Neoplasias de la Columna Vertebral/tratamiento farmacológico , Terapéutica/métodos , Traumatología , Procedimientos Ortopédicos , Ortopedia , NeoplasiasRESUMEN
The influence of operational variables in the pulping of vine shoots by use of ethanolamine [viz. temperature (155-185 degrees C), cooking time (30-90min) and ethanolamine concentration (50-70% v/v)] on the properties of the resulting pulp (viz. yield, kappa index, viscosity and drainability) was studied. A central composite factorial design was used in conjunction with the software BMDP and ANFIS Edit Matlab 6.5 to develop polynomial and fuzzy neural models that reproduced the experimental results of the dependent variables with errors less than 10%. Both types of models are therefore effective with a view to simulating the ethanolamine pulping process. Based on the proposed equations, the best choice is to use values of the operational valuables resulting in near-optimal pulp properties while saving energy and immobilized capital on industrial facilities by using lower temperatures and shorter processing times. One combination leading to near-optimal properties with reduced costs is using a temperature of 180 degrees C and an ethanolamine concentration of 60% for 60min, to obtain pulp with a viscosity of 6.13% lower than the maximum value (932.8ml/g) and a drainability of 5.49% lower than the maximum value (71 (o)SR).
Asunto(s)
Etanolamina/química , Lógica Difusa , Papel , Brotes de la Planta/química , Conservación de los Recursos Naturales , Calor , Industrias , Redes Neurales de la Computación , Factores de TiempoRESUMEN
OBJECTIVES: To define a process management model for a hospital pharmacy in order to measure, analyse and make continuous improvements in patient safety and healthcare quality. MATERIAL AND METHODS: In order to implement process management, Igualada Hospital was divided into different processes, one of which was the Hospital Pharmacy. A multidisciplinary management team was given responsibility for each process. For each sub-process one person was identified to be responsible, and a working group was formed under his/her leadership. With the help of each working group, a risk analysis using failure modes and effects analysis (FMEA) was performed, and the corresponding improvement actions were implemented. Sub-process indicators were also identified, and different process management mechanisms were introduced. RESULTS: The first risk analysis with FMEA produced more than thirty preventive actions to improve patient safety. Later, the weekly analysis of errors, as well as the monthly analysis of key process indicators, permitted us to monitor process results and, as each sub-process manager participated in these meetings, also to assume accountability and responsibility, thus consolidating the culture of excellence. CONCLUSIONS: The introduction of different process management mechanisms, with the participation of people responsible for each sub-process, introduces a participative management tool for the continuous improvement of patient safety and healthcare quality.
Asunto(s)
Seguridad del Paciente , Servicio de Farmacia en Hospital , Calidad de la Atención de Salud , Administración de la Seguridad , Humanos , Servicio de Farmacia en Hospital/normasRESUMEN
We report our first performance of a multiple anterior thoracoscopic epiphysiodesis in the treatment of a crankshaft phenomenon. In the last 2 years, video-assisted thoracoscopy has been introduced as a new therapeutic technique in the field of spinal diseases. Its use has been most documented in the treatment of vertebral abscesses and disc herniations, while its performance in treating deformities is less known. The patient in our case was an 11-year-old boy with a 7-year history of aggressive left thoracic idiopathic scoliosis that had previously needed three subcutaneous instrumentations and finally a Cotrel-Dubousset-instrumented arthrodesis. Following these operations, a continuous clinical and radiographical evolution of the curve was recorded and an anterior T6-T11 video-assisted thoracoscopic epiphysiodesis was therefore performed. The patient did not need postoperative narcotics; Argyle chest tubes were removed after 48h with only 150ml of serohaematic drainage, no blood transfusion was required. One year after the intervention, we found a well-consolidated T6-T11 arthrodesis with no evolution of the deformity. The endoscopic technique allowed us to perform an extensive anterior arthrodesis using only three small incisions, with a reduction of bed-confinement to 3 days and reduced postthoracotomy pain.
Asunto(s)
Endoscopía , Escoliosis/cirugía , Toracoscopía , Artrodesis , Niño , Epífisis/cirugía , Humanos , Masculino , Dispositivos de Fijación OrtopédicaRESUMEN
Objetivos. Definir un modelo de gestión por procesos de una Farmacia Hospitalaria para medir, analizar y realizar la mejora continúa en seguridad y calidad asistencial. Material y métodos. En el marco de implantación de la gestión por procesos, el Hospital de Igualada se dividió en varios procesos, uno de los cuales fue el proceso de Farmacia Hospitalaria. Primero se nombró un equipo de gestión para cada proceso. Después se definió un pequeño grupo de trabajo para cada subproceso con su respectivo responsable. Con la ayuda de estos grupos se realizaron el análisis de riesgos aplicando el Análisis Modal de Fallos y Efectos (AMFE) y la implantación de las acciones de mejora resultantes. Se definieron indicadores para cada subproceso y se establecieron diferentes mecanismos de gestión por procesos. Resultados. Primero, el análisis de riesgos con AMFE generó más de una treintena de acciones preventivas para mejorar la seguridad del paciente. Después, tanto el análisis semanal de incidencias como el análisis mensual de los indicadores nos permitió la monitorización y gestión basada en datos objetivos de los resultados claves. Además, el tener a una persona responsable de los resultados de cada subproceso nos permitió la implicación y compromiso del personal creándose la cultura de excelencia. Conclusiones. La introducción de diferentes mecanismos de gestión por procesos, con la participación del personal responsable para cada subproceso, introduce una herramienta de gestión participativa para la mejora continua de la seguridad y calidad asistencial(AU)
Objectives. To define a process management model for a hospital pharmacy in order to measure, analyse and make continuous improvements in patient safety and healthcare quality. Material and methods. In order to implement process management, Igualada Hospital was divided into different processes, one of which was the Hospital Pharmacy. A multidisciplinary management team was given responsibility for each process. For each sub-process one person was identified to be responsible, and a working group was formed under his/her leadership. With the help of each working group, a risk analysis using failure modes and effects analysis (FMEA) was performed, and the corresponding improvement actions were implemented. Sub-process indicators were also identified, and different process management mechanisms were introduced. Results. The first risk analysis with FMEA produced more than thirty preventive actions to improve patient safety. Later, the weekly analysis of errors, as well as the monthly analysis of key process indicators, permitted us to monitor process results and, as each sub-process manager participated in these meetings, also to assume accountability and responsibility, thus consolidating the culture of excellence. Conclusions. The introduction of different process management mechanisms, with the participation of people responsible for each sub-process, introduces a participative management tool for the continuous improvement of patient safety and healthcare quality(AU)
Asunto(s)
Humanos , Masculino , Femenino , Evaluación de Procesos y Resultados en Atención de Salud/normas , Evaluación de Procesos y Resultados en Atención de Salud , /métodos , Servicio de Farmacia en Hospital/métodos , Servicio de Farmacia en Hospital/normas , Servicio de Farmacia en Hospital , Seguridad del Paciente/normas , Errores de Medicación/ética , Errores de Medicación/tendencias , Servicio de Farmacia en Hospital/organización & administración , Servicio de Farmacia en Hospital/tendencias , Seguridad del Paciente/economía , Seguridad del Paciente/legislación & jurisprudencia , Calidad de la Atención de Salud/normas , Calidad de la Atención de Salud , Citostáticos/farmacología , Nutrición ParenteralRESUMEN
La ciudad de Mar del Plata posee un ecosistema cuyas características difieren notablemente de otras ciudades de la provincia, por lo que es fundamental la obtención de límites locales. Este trabajo tiene como objetivo la actualización de los límites de vuelco vigentes para efluentes líquidos a colectora cloacal, establecidos por Resolución Provincial y Municipal. Para esto, se analizó la afectación del mar y del sistema cloacal por el vuelco de efluentes industriales, utilizando información propia. Los resultados obtenidos fueron consensuados posteriormente en un Foro Público