RESUMEN
The analysis of the nucleoprotein gene of 77 Puumala hantavirus strains detected in human samples in France during 2012-2016 showed that all belonged to the Central European lineage. We observed 2 main clusters, geographically structured; one included strains with the Q64 signature and the other strains with the R64 signature.
Asunto(s)
Arvicolinae/virología , Infecciones por Hantavirus/virología , Orthohantavirus/genética , Virus Puumala/genética , Animales , Análisis por Conglomerados , Francia/epidemiología , Genómica , Genotipo , Geografía , Orthohantavirus/aislamiento & purificación , Infecciones por Hantavirus/epidemiología , Humanos , Filogenia , Virus Puumala/aislamiento & purificación , ZoonosisRESUMEN
We report detection of Seoul virus in 3 patients in France over a 2-year period. These patients accounted for 3 of the 4 Seoul virus infections among 434 hantavirus infections (1.7%) reported during this time. More attention should be given to this virus in Europe where surveillance has been focused mostly on Puumala and Dobrava-Belgrade hantaviruses.
Asunto(s)
Fiebre Hemorrágica con Síndrome Renal/diagnóstico , Fiebre Hemorrágica con Síndrome Renal/epidemiología , Virus Seoul , Adulto , Animales , Anticuerpos Antivirales , Francia/epidemiología , Fiebre Hemorrágica con Síndrome Renal/virología , Humanos , Masculino , Ratas , Adulto JovenRESUMEN
We report an infection with Tula virus in June 2015, leading to hospitalisation, in a patient living approximately 60 km east of Paris with no previous remarkable medical history. Clinical symptoms were limited to a fever syndrome with severe headache. The main laboratory findings included thrombocytopenia and elevated transaminase levels. Based on S (small) gene sequence analysis, the strain affecting the patient was closely related to strains detected in Central Europe, especially to a south-east German strain.