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1.
Phys Rev Lett ; 129(14): 145301, 2022 Sep 30.
Artículo en Inglés | MEDLINE | ID: mdl-36240399

RESUMEN

Superfluid ^{4}He (He II) is a widely studied model system for exploring finite-size effects in strongly confined geometries. Here, we study He II confined in millimeter-scale channels of 25 and 50 nm height at high pressures using a nanofluidic Helmholtz resonator. We find that the superfluid density is measurably suppressed in the confined geometry from the transition temperature down to 0.6 K. Importantly, this suppression can be accounted for by rotonlike thermal excitations with an energy gap of 5 K. We show that the surface-bound excitations lead to the previously unexplained lack of finite-size scaling of suppression of the superfluid density.

2.
Phys Rev Lett ; 125(2): 025301, 2020 Jul 10.
Artículo en Inglés | MEDLINE | ID: mdl-32701340

RESUMEN

Turbulent flow restricted to two dimensions can spontaneously develop order on large scales, defying entropy expectations and in sharp contrast with turbulence in three dimensions where nonlinear turbulent processes act to destroy large-scale order. In this work we report the observation of unusual turbulent behavior in steady-state flow of superfluid ^{4}He-a liquid with vanishing viscosity and discrete vorticity-in a nearly two-dimensional channel. Surprisingly, for a range of experimental parameters, turbulence is observed to exist in two bistable states. This bistability can be well explained by the appearance of large-scale regions of flow of opposite vorticity.

3.
Phys Rev Lett ; 124(1): 015301, 2020 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-31976679

RESUMEN

Superfluid ^{3}He under nanoscale confinement has generated significant interest due to the rich spectrum of phases with complex order parameters that may be stabilized. Experiments have uncovered a variety of interesting phenomena, but a complete picture of superfluid ^{3}He under confinement has remained elusive. Here, we present phase diagrams of superfluid ^{3}He under varying degrees of uniaxial confinement, over a wide range of pressures, which elucidate the progressive stability of both the A phase, as well as a growing region of stable pair density wave state.

4.
Phys Rev Lett ; 123(9): 093603, 2019 Aug 30.
Artículo en Inglés | MEDLINE | ID: mdl-31524457

RESUMEN

Mechanical modes are a potentially useful resource for quantum information applications, such as quantum-level wavelength transducers, due to their ability to interact with electromagnetic radiation across the spectrum. A significant challenge for wavelength transducers is thermomechanical noise in the mechanical mode, which pollutes the transduced signal with thermal states. In this Letter, we eliminate thermomechanical noise in the GHz-frequency mechanical breathing mode of a piezoelectric optomechanical crystal using cryogenic cooling in a dilution refrigerator. We optically measure an average thermal occupancy of the mechanical mode of only 0.7±0.4 phonons, providing a path towards low-noise microwave-to-optical conversion in the quantum regime.

5.
Opt Express ; 26(9): 11201-11212, 2018 Apr 30.
Artículo en Inglés | MEDLINE | ID: mdl-29716044

RESUMEN

We describe a theoretical study of dipole emitters inside buckled-dome Fabry-Perot cavities with Si/SiO2-based omnidirectional Bragg mirrors. The low penetration depth of the mirrors contributes to low mode volumes, potentially enabling large enhancement of spontaneous emission into moderate-quality-factor cavity modes. Furthermore, the omnidirectional mirrors can significantly inhibit background emission. For a representative cavity operating in a fundamental spatial mode regime at λ ~1550 nm, and an optimally located emitter, we predict simultaneous enhancement of emission into the cavity mode by ~120 and suppression of background emission by ~25, implying the potential for a cooperativity C ~1500. This is combined with Q ~103, significantly lower than is required to attain similar values of C without background inhibition, and thus implying better compatibility for broad line-width emitters.

7.
Phys Rev Lett ; 119(17): 175702, 2017 Oct 27.
Artículo en Inglés | MEDLINE | ID: mdl-29219452

RESUMEN

Nanosecond in situ x-ray diffraction and simultaneous velocimetry measurements were used to determine the crystal structure and pressure, respectively, of ramp-compressed aluminum at stress states between 111 and 475 GPa. The solid-solid Al phase transformations, fcc-hcp and hcp-bcc, are observed at 216±9 and 321±12 GPa, respectively, with the bcc phase persisting to 475 GPa. The high-pressure crystallographic texture of the hcp and bcc phases suggests close-packed or nearly close-packed lattice planes remain parallel through both transformations.

8.
Opt Lett ; 40(22): 5375-8, 2015 Nov 15.
Artículo en Inglés | MEDLINE | ID: mdl-26565878

RESUMEN

We describe optical bistability in monolithically integrated, curved-mirror Fabry-Perot microcavities. The cavities were fabricated by controlled formation of circular delamination buckles within sputtered Si/SiO(2) multilayers. The dominant source of the bistability is heating due to residual absorption in the mirror layers, which leads to out-of-plane deflection of the buckled mirror. Hysteresis occurs for submilliwatt input powers.

10.
Nano Lett ; 14(5): 2541-5, 2014 May 14.
Artículo en Inglés | MEDLINE | ID: mdl-24720496

RESUMEN

We study high-Q nanostrings that are joined end-to-end to form coupled linear arrays. Whereas isolated individual resonators exhibit sinusoidal vibrational modes with an almost perfectly harmonic spectrum, the modes of the interacting strings are substantially hybridized. Even far-separated strings can show significantly correlated displacement. This remote coupling property is exploited to quantify the deposition of femtogram-scale masses with string-by-string positional discrimination based on measurements of one string only.

11.
Anal Chem ; 86(22): 11368-72, 2014 Nov 18.
Artículo en Inglés | MEDLINE | ID: mdl-25329453

RESUMEN

We demonstrate detection of femtogram-scale quantities of the explosive molecule 1,3,5-trinitroperhydro-1,3,5-triazine (RDX) via combined nanomechanical photothermal spectroscopy and mass desorption. Photothermal spectroscopy provides a spectroscopic fingerprint of the molecule, which is unavailable using mass adsorption/desorption alone. Our measurement, based on thermomechanical measurement of silicon nitride nanostrings, represents the highest mass resolution ever demonstrated via nanomechanical photothermal spectroscopy. This detection scheme is quick, label-free, and is compatible with parallelized molecular analysis of multicomponent targets.


Asunto(s)
Nanotecnología , Temperatura , Triazinas/análisis , Estructura Molecular , Nanopartículas/análisis , Procesos Fotoquímicos , Compuestos de Silicona/análisis , Análisis Espectral
12.
Science ; 372(6546): 1063-1068, 2021 06 04.
Artículo en Inglés | MEDLINE | ID: mdl-34083483

RESUMEN

New techniques are advancing the frontier of high-pressure physics beyond 1 terapascal, leading to new discoveries and offering stringent tests for condensed-matter theory and advanced numerical methods. However, the ability to absolutely determine the pressure state remains challenging, and well-calibrated pressure-density reference materials are required. We conducted shockless dynamic compression experiments at the National Ignition Facility and the Z machine to obtain quasi-absolute, high-precision, pressure-density equation-of-state data for gold and platinum. We derived two experimentally constrained pressure standards to terapascal conditions. Establishing accurate experimental determinations of extreme pressure will facilitate better connections between experiments and theory, paving the way toward improving our understanding of material response to these extreme conditions.

13.
Appl Phys Lett ; 116(17)2020.
Artículo en Inglés | MEDLINE | ID: mdl-34815582

RESUMEN

Microwave-to-optical transduction has received a great deal of interest from the cavity optomechanics community as a landmark application for electro-optomechanical systems. In this Letter, we demonstrate a novel transducer that combines high-frequency mechanical motion and a microwave cavity for the first time. The system consists of a 3D microwave cavity and a gallium arsenide optomechanical crystal, which has been placed in the microwave electric field maximum. This allows the microwave cavity to actuate the gigahertz-frequency mechanical breathing mode in the optomechanical crystal through the piezoelectric effect, which is then read out using a telecom optical mode. The gallium arsenide optomechanical crystal is a good candidate for low-noise microwave-to-telecom transduction, as it has been previously cooled to the mechanical ground state in a dilution refrigerator. Moreover, the 3D microwave cavity architecture can naturally be extended to couple to superconducting qubits and to create hybrid quantum systems.

14.
Science ; 220(4593): 204-6, 1983 Apr 08.
Artículo en Inglés | MEDLINE | ID: mdl-17795831

RESUMEN

Bacteria-free suspensions of larvae of Strongylocentrotus purpuratus (Stimpson) were prepared without the use of antibiotics. Net rates of removal of 18 amino acids, each supplied at 125 nanomoles per liter, and the appearance of ammonia were measured by high-performance liquid chromatography. Taurine and acidic and basic amino acids were not taken up. Removal of neutral amino acids from the medium occurred at rates adequate to contribute to the carbon and nitrogen balance of the larvae at ecologically relevant substrate concentrations.

15.
Science ; 216(4552): 1317-9, 1982 Jun 18.
Artículo en Inglés | MEDLINE | ID: mdl-7043737

RESUMEN

A treponema-like spirochete was detected in and isolated from adult Ixodes dammini, the incriminated tick vector of Lyme disease. Causally related to the spirochetes may be long-lasting cutaneous lesions that appeared on New Zealand White rabbits 10 to 12 weeks after infected ticks fed on them. Samples of serum from patients with Lyme disease were shown by indirect immunofluorescence to contain antibodies to this agent. It is suggested that the newly discovered spirochete is involved in the etiology of Lyme disease.


Asunto(s)
Vectores Arácnidos/microbiología , Artritis Infecciosa/microbiología , Infecciones por Spirochaetales/microbiología , Garrapatas/microbiología , Animales , Sistema Digestivo/microbiología , Técnica del Anticuerpo Fluorescente , Humanos , Microscopía Electrónica , Microvellosidades/microbiología , Microvellosidades/ultraestructura , Conejos , Estaciones del Año , Spirochaetales/ultraestructura
16.
JOM (1989) ; 60(3): 33-37, 2008 Mar 01.
Artículo en Inglés | MEDLINE | ID: mdl-20617106

RESUMEN

The therapeutic application of nanomaterials has been a focus of numerous studies in the past decade. Due to its unique redox properties, cerium oxide (ceria) is finding widespread use in the treatment of medical disorders caused by the reactive oxygen intermediates (ROI). The radical-scavenging role of ceria nanoparticles (nanoceria) have been established, as well as the autocatalytic ability of nanoceria to regenerate under various environmental conditions. The synthesis of nanoceria in biocompatible media has also been reported along with cell viability in order to determine the potential use of nanoceria in biomedical applications.

17.
Rev Sci Instrum ; 89(11): 114704, 2018 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-30501360

RESUMEN

A wide variety of applications of microwave cavities, such as measurement and control of superconducting qubits, magnonic resonators, and phase noise filters, would be well served by having a highly tunable microwave resonance. Often this tunability is desired in situ at low temperatures, where one can take advantage of superconducting cavities. To date, such cryogenic tuning while maintaining a high quality factor has been limited to ∼500 MHz. Here we demonstrate a three-dimensional superconducting microwave cavity that shares one wall with a pressurized volume of helium. Upon pressurization of the helium chamber, the microwave cavity is deformed, which results in in situ tuning of its resonant frequency by more than 5 GHz, greater than 60% of the original 8 GHz resonant frequency. The quality factor of the cavity remains approximately constant at ≈7 × 103 over the entire range of tuning. As a demonstration of its usefulness, we implement a tunable cryogenic phase noise filter, which reduces the phase noise of our source by approximately 10 dB above 400 kHz.

18.
Transplant Proc ; 50(10): 3501-3507, 2018 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-30586837

RESUMEN

BACKGROUND: Patients with cirrhosis and end-stage liver disease (ESLD) develop severe nutrition deficits that affect morbidity and mortality. Laboratory measures of nutrition fail to fully assess clinical deficits in muscle mass and fat stores. This study employs computed tomography imaging to assess muscle mass and subcutaneous and visceral fat stores in patients with ESLD. METHODS: This 1:1 case-control study design compares ESLD patients with healthy controls. Study patients were selected from a database of ESLD patients using a stratified method to assure a representative sample based on age, body mass index (BMI), sex, and model for end-stage liver disease score (MELD). Control patients were trauma patients with a low injury severity score (<10) who had a computed tomography scan during evaluation. Cases and controls were matched for age ± 5 years, sex, and BMI ± 2. RESULTS: There were 90 subjects and 90 controls. ESLD patients had lower albumin levels (P < .001), but similar total protein levels (P = .72). ESLD patients had a deficit in muscle mass (-19%, P < .001) and visceral fat (-13%, P < .001), but similar subcutaneous fat (-1%, P = .35). ESLD patients at highest risk for sarcopenia included those over age 60, BMI<25.0, and female sex. We found degree of sarcopenia to be independent of model for end-stage liver disease score. CONCLUSIONS: These results support previous research demonstrating substantial nutrition deficits in ESLD patients that are not adequately measured by laboratory testing. Patients with ESLD have significant deficits of muscle and visceral fat stores, but a similar amount of subcutaneous fat.


Asunto(s)
Enfermedad Hepática en Estado Terminal/diagnóstico por imagen , Trasplante de Hígado/efectos adversos , Complicaciones Posoperatorias/diagnóstico por imagen , Sarcopenia/diagnóstico por imagen , Tomografía Computarizada por Rayos X/métodos , Adolescente , Adulto , Índice de Masa Corporal , Estudios de Casos y Controles , Enfermedad Hepática en Estado Terminal/complicaciones , Femenino , Humanos , Grasa Intraabdominal/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Músculo Esquelético/diagnóstico por imagen , Evaluación Nutricional , Estado Nutricional , Complicaciones Posoperatorias/etiología , Periodo Posoperatorio , Sarcopenia/etiología , Grasa Subcutánea/diagnóstico por imagen , Adulto Joven
19.
Colloids Surf B Biointerfaces ; 54(2): 200-10, 2007 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-17123793

RESUMEN

Whipped foams (10%, w/v protein, pH 7.0) were prepared from commercially available samples of whey protein isolate (WPI) and egg white protein (EWP), and subsequently compared based on yield stress (tau(0)), overrun and drainage stability. Adsorption rates and interfacial rheological measurements at a model air/water interface were quantified via pendant drop tensiometry to better understand foaming differences among the ingredients. The highest tau(0) and resistance to drainage were observed for standard EWP, followed by EWP with added 0.1% (w/w) sodium lauryl sulfate, and then WPI. Addition of 25% (w/w) sucrose increased tau(0) and drainage resistance of the EWP-based ingredients, whereas it decreased tau(0) of WPI foams and minimally affected their drainage rates. These differing sugar effects were reflected in the interfacial rheological measurements, as sucrose addition increased the dilatational elasticity for both EWP-based ingredients, while decreasing this parameter for WPI. Previously observed relationships between tau(0) and interfacial rheology did not hold across the protein types; however, these measurements did effectively differentiate foaming behaviors within EWP-based ingredients and within WPI. Interfacial data was also collected for purified beta-lactoglobulin (beta-lg) and ovalbumin, the primary proteins of WPI and EWP, respectively. The addition of 25% (w/w) sucrose increased the dilatational elasticity for adsorbed layers of beta-lg, while minimally affecting the interfacial rheology of adsorbed ovalbumin, in contrast to the response of WPI and EWP ingredients. These experiments underscore the importance of utilizing the same materials for interfacial measurements as used for foaming experiments, if one is to properly infer interfacial information/mechanisms and relate this information to bulk foaming measurements. The effects of protein concentration and measurement time on interfacial rheology were also considered as they relate to bulk foam properties. This data should be of practical assistance to those designing aerated food products, as it has not been previously reported that sucrose addition improves the foaming characteristics of EWP-based ingredients while negatively affecting the foaming behavior of WPI, as these types of protein isolates are common to the food industry.


Asunto(s)
Proteínas del Huevo/química , Proteínas de la Leche/química , Animales , Bovinos , Pollos , Reología , Albúmina Sérica/química , Proteína de Suero de Leche
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