1.
Ann Vasc Surg
; 24(3): 415.e5-7, 2010 Apr.
Artículo
en Inglés
| MEDLINE
| ID: mdl-19932950
RESUMEN
Antithrombin is a potent inhibitor of the coagulation cascade exerting its primary effects on activated factors X, IX and II. It is the mechanism by which heparin and low-molecular weight heparin cause anti-coagulation. Deficiency of antithrombin presents as a hypercoagulable state, and may result in unexplained deep venous thrombosis, arterial thrombosis and systemic embolization.