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1.
Ophthalmologe ; 111(11): 1073-6, 2014 Nov.
Artículo en Alemán | MEDLINE | ID: mdl-24961174

RESUMEN

CASE REPORT: A 54-year-old female presented with a progressive swelling of the upper eyelid since 6 months. Magnetic resonance imaging (MRI) showed an extraconal supratemporal orbital lesion. After resection the histopathological diagnosis confirmed a Merkel cell carcinoma in the lacrimal gland. CLINICAL COURSE: Due to an incomplete resection the patient underwent adjuvant radiochemotherapy and is relapse-free for 1.5 years. CONCLUSION: Merkel cell carcinoma (MCC) is a rare neuroendocrine tumor, usually occurring on sun-exposed skin and in 10% in the region of the eyelids. The occurrence of MCC in the lacrimal gland is even less common with only two published cases.


Asunto(s)
Carcinoma de Células de Merkel/diagnóstico , Carcinoma de Células de Merkel/terapia , Neoplasias de los Párpados/diagnóstico , Neoplasias de los Párpados/terapia , Neoplasias Cutáneas/diagnóstico , Neoplasias Cutáneas/terapia , Quimioradioterapia Adyuvante , Diagnóstico Diferencial , Femenino , Humanos , Imagen por Resonancia Magnética , Persona de Mediana Edad , Enfermedades Raras/diagnóstico , Enfermedades Raras/patología , Resultado del Tratamiento
2.
Rofo ; 185(9): 830-7, 2013 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-23888471

RESUMEN

PURPOSE: Generally, high-resolution MRI of the eye is performed with small loop surface coils. The purpose of this phantom and patient study was to investigate the influence of magnetic field strength and receiver coils on image quality in ocular MRI. MATERIALS AND METHODS: The eyeball and the complex geometry of the facial bone were simulated by a skull phantom with swine eyes. MR images were acquired with two small loop surface coils with diameters of 4 cm and 7 cm and with a multi-channel head coil at 1.5 and 3 Tesla, respectively. Furthermore, MRI of the eye was performed prospectively in 20 patients at 1.5 Tesla (7 cm loop surface coil) and 3 Tesla (head coil). These images were analysed qualitatively and quantitatively and statistical significance was tested using the Wilcoxon-signed-rank test (a p-value of less than 0.05 was considered to indicate statistical significance). RESULTS: The analysis of the phantom images yielded the highest mean signal-to-noise ratio (SNR) at 3 Tesla with the use of the 4 cm loop surface coil. In the phantom experiment as well as in the patient studies the SNR was higher at 1.5 Tesla by applying the 7 cm surface coil than at 3 Tesla by applying the head coil. Concerning the delineation of anatomic structures no statistically significant differences were found. CONCLUSION: Our results show that the influence of small loop surface coils on image quality (expressed in SNR) in ocular MRI is higher than the influence of the magnetic field strength. The similar visibility of detailed anatomy leads to the conclusion that the image quality of ocular MRI at 3 Tesla remains acceptable by applying the head coil as a receiver coil.


Asunto(s)
Ojo/patología , Aumento de la Imagen/instrumentación , Aumento de la Imagen/métodos , Interpretación de Imagen Asistida por Computador/instrumentación , Interpretación de Imagen Asistida por Computador/métodos , Campos Magnéticos , Imagen por Resonancia Magnética/instrumentación , Imagen por Resonancia Magnética/métodos , Melanoma/diagnóstico , Fantasmas de Imagen , Neoplasias de la Úvea/diagnóstico , Adulto , Anciano , Animales , Artefactos , Movimientos Oculares/fisiología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Sensibilidad y Especificidad , Porcinos
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