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1.
Synthetic studies towards isomeric pyrazolopyrimidines as potential ATP synthesis inhibitors of Mycobacterium tuberculosis. Structural correction of reported N-(6-(2-(dimethylamino)ethoxy)-5-fluoropyridin-3-yl)-2-(4-fluorophenyl)-5-(trifluoromethyl)pyrazolo[1,5-α]pyrimidin-7-amine.
Tetrahedron Lett
; 90: None, 2022 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35140452
2.
Synthesis and biological evaluation of solubilized sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474.
Bioorg Med Chem
; 27(8): 1529-1545, 2019 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30850264
3.
Novel pyrazolo[1,5-a]pyridines with improved aqueous solubility as p110α-selective PI3 kinase inhibitors.
Bioorg Med Chem Lett
; 27(2): 187-190, 2017 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27923617
4.
Synthesis and biological evaluation of sulfonamide analogues of the phosphatidylinositol 3-kinase inhibitor ZSTK474.
Bioorg Med Chem
; 25(20): 5859-5874, 2017 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28958845
5.
Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates.
Bioorg Med Chem
; 24(22): 6075-6081, 2016 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27745990
6.
Fragment-based and structure-guided discovery of perforin inhibitors.
Eur J Med Chem
; 261: 115786, 2023 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37716187
7.
Novel pyrazolo[1,5-a]pyridines as p110α-selective PI3 kinase inhibitors: Exploring the benzenesulfonohydrazide SAR.
Bioorg Med Chem
; 20(1): 58-68, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22177407
8.
Synthesis and Structure-Activity Relationships for the Anti-Mycobacterial Activity of 3-Phenyl-N-(Pyridin-2-ylmethyl)Pyrazolo[1,5-a]Pyrimidin-7-Amines.
Pharmaceuticals (Basel)
; 15(9)2022 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36145345
9.
Inhibition of the Cytolytic Protein Perforin Prevents Rejection of Transplanted Bone Marrow Stem Cells in Vivo.
J Med Chem
; 63(5): 2229-2239, 2020 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31525966
10.
Biological characterization of SN32976, a selective inhibitor of PI3K and mTOR with preferential activity to PI3Kα, in comparison to established pan PI3K inhibitors.
Oncotarget
; 8(29): 47725-47740, 2017 Jul 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28537878
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