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1.
Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration.
Proc Natl Acad Sci U S A
; 119(11): e2121609119, 2022 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35259016
2.
Pharmacokinetics and Safety Studies in Rodent Models Support Development of EPICERTIN as a Novel Topical Wound-Healing Biologic for Ulcerative Colitis.
J Pharmacol Exp Ther
; 380(3): 162-170, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35058349
3.
Enhancement of sensitivity and quantification quality in the LC-MS/MS measurement of large biomolecules with sum of MRM (SMRM).
Anal Bioanal Chem
; 414(5): 1933-1947, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-34997251
4.
Improving solubility and oral bioavailability of a novel antimalarial prodrug: comparing spray-dried dispersions with self-emulsifying drug delivery systems.
Pharm Dev Technol
; 25(5): 625-639, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-32031478
5.
Reversal of Tabun Toxicity Enabled by a Triazole-Annulated Oxime Library-Reactivators of Acetylcholinesterase.
Chemistry
; 25(16): 4100-4114, 2019 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30458057
6.
In Vitro and In Vivo Activity of Amiodarone Against Ebola Virus.
J Infect Dis
; 218(suppl_5): S592-S596, 2018 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-30016444
7.
Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29133569
8.
Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure.
J Pharmacol Exp Ther
; 367(2): 363-372, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30190337
9.
Correction to: Enhancement of sensitivity and quantification quality in the LC-MS/MS measurement of large biomolecules with sum of MRM (SMRM).
Anal Bioanal Chem
; 414(8): 2787, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-35133454
10.
Utilizing native fluorescence imaging, modeling and simulation to examine pharmacokinetics and therapeutic regimen of a novel anticancer prodrug.
BMC Cancer
; 16: 524, 2016 07 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-27457630
11.
Formulation approaches to improving the delivery of an antiviral drug with activity against seasonal flu.
Pharm Dev Technol
; 20(2): 169-75, 2015 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24218989
12.
(R,S)-Ketamine metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine increase the mammalian target of rapamycin function.
Anesthesiology
; 121(1): 149-59, 2014 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-24936922
13.
Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes.
Biochem J
; 450(1): 231-42, 2013 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23216060
14.
Evaluating the toxicity of novel Zn-DTPA tablet formulation in dogs and rats.
Drug Dev Res
; 75(1): 37-46, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24648048
15.
Liraglutide 3.0 mg (Saxenda©) for Weight Loss and Remission of Pre-Diabetes. Real-World Clinical Evaluation of Effectiveness among Patients Awaiting Bariatric Surgery.
Obes Surg
; 34(1): 286-289, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-38012508
16.
Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases.
J Biol Chem
; 287(15): 11798-809, 2012 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-22343626
17.
Efficacy of the GluK1/AMPA receptor antagonist LY293558 against seizures and neuropathology in a soman-exposure model without pretreatment and its pharmacokinetics after intramuscular administration.
J Pharmacol Exp Ther
; 344(1): 133-40, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23042954
18.
Granulocyte Colony-Stimulating Factor (Neupogen®; Filgrastim) Accelerates Neutrophil Recovery in a Rodent Model of Sulfur Mustard-Induced Hematologic Toxicity.
Disaster Med Public Health Prep
; 17: e550, 2023 Dec 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38044835
19.
Identification of (+)-erythro-mefloquine as an active enantiomer with greater efficacy than mefloquine against Mycobacterium avium infection in mice.
Antimicrob Agents Chemother
; 56(8): 4202-6, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22615290
20.
Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies.
Antimicrob Agents Chemother
; 56(7): 3690-9, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22508306