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1.
J Clin Child Adolesc Psychol ; 48(1): 54-67, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-27617781

RESUMEN

We examined the reciprocal relationships among positive future expectations, expected threats to future safety, depression, and individual substance use and delinquency using 4 waves of data (N = 248-338) from African American and Latino adolescent male participants in the Chicago Youth Development Study. Individual positive future expectations and expected threats to safety were assessed at each wave and modeled as latent constructs. Individual substance use and delinquency were assessed at each wave and represented as ordinal variables ranging from low to high. Categorical autoregressive cross-lagged structural models were used to examine the hypothesized reciprocal relationships between both aspects of future expectations construct and risk behavior across adolescence. Analyses show that future expectations has important effects on youth substance use and involvement in delinquency, both of which in turn decrease positive expectations and increase expectation of threats to future safety across adolescence. Similarly, low positive expectations for the future continued to predict increased substance use and involvement in delinquency. The expected threats to safety construct was significantly correlated with delinquency within time. These effects are observed across adolescence after controlling for youth depression and race. Findings support the reciprocal effects hypothesis of a negative reinforcing cycle in the relationships between future expectations and both substance use and involvement in delinquent behavior across adolescence. The enduring nature of these relationships underscores the importance of future expectation as a potential change mechanism for intervention and prevention efforts to promote healthy development; vulnerable racial and ethnic minority male adolescents may especially benefit from such intervention.


Asunto(s)
Conducta del Adolescente/psicología , Anticipación Psicológica , Delincuencia Juvenil/psicología , Delincuencia Juvenil/tendencias , Asunción de Riesgos , Adolescente , Conducta del Adolescente/fisiología , Anticipación Psicológica/fisiología , Estudios de Cohortes , Predicción , Humanos , Estudios Longitudinales , Masculino , Motivación/fisiología , Estudios Prospectivos , Distribución Aleatoria , Trastornos Relacionados con Sustancias/diagnóstico , Trastornos Relacionados con Sustancias/psicología , Trastornos Relacionados con Sustancias/terapia
2.
J Clin Child Adolesc Psychol ; 46(1): 125-135, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-27653968

RESUMEN

The current study examined a model of desensitization to community violence exposure-the pathologic adaptation model-in male adolescents of color. The current study included 285 African American (61%) and Latino (39%) male adolescents (W1 M age = 12.41) from the Chicago Youth Development Study to examine the longitudinal associations between community violence exposure, depressive symptoms, and violent behavior. Consistent with the pathologic adaptation model, results indicated a linear, positive association between community violence exposure in middle adolescence and violent behavior in late adolescence, as well as a curvilinear association between community violence exposure in middle adolescence and depressive symptoms in late adolescence, suggesting emotional desensitization. Further, these effects were specific to cognitive-affective symptoms of depression and not somatic symptoms. Emotional desensitization outcomes, as assessed by depressive symptoms, can occur in male adolescents of color exposed to community violence and these effects extend from middle adolescence to late adolescence.


Asunto(s)
Conducta del Adolescente/psicología , Agresión/psicología , Negro o Afroamericano/psicología , Exposición a la Violencia/psicología , Hispánicos o Latinos/psicología , Adolescente , Depresión/psicología , Femenino , Humanos , Control Interno-Externo , Masculino , Factores de Riesgo
3.
J Clin Child Adolesc Psychol ; 46(6): 824-839, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-26514393

RESUMEN

Researchers have long observed that problem behaviors tend to cluster together, particularly among adolescents. Epidemiological studies have suggested that this covariation is due, in part, to common genetic influences, and a number of plausible candidates have emerged as targets for investigation. To date, however, genetic association studies of these behaviors have focused mostly on unidimensional models of individual phenotypes within European American samples. Herein, we compared a series of confirmatory factor models to best characterize the structure of problem behavior (alcohol and marijuana use, sexual behavior, and disruptive behavior) within a representative community-based sample of 592 low-income African American adolescents (50.3% female), ages 13 to 18. We further explored the extent to which 3 genes previously implicated for their role in similar behavioral dimensions (CHRM2, GABRA2, and OPRM1) independently accounted for variance within factors specified in the best-fitting model. Supplementary analyses were conducted to derive comparative estimates for the predictive utility of these genes in more traditional unidimensional models. Findings provide initial evidence for a bifactor structure of problem behavior among African American adolescents and highlight novel genetic correlates of specific behavioral dimensions otherwise undetected in an orthogonal syndromal factor. Implications of this approach include increased precision in the assessment of problem behavior, with corresponding increases in the reliability and validity of identified genetic associations. As a corollary, the comparison of primary and supplementary association analyses illustrates the potential for overlooking and/or overinterpreting meaningful genetic effects when failing to adequately account for phenotypic complexity.


Asunto(s)
Conducta del Adolescente/psicología , Negro o Afroamericano/genética , Problema de Conducta/psicología , Adolescente , Femenino , Humanos , Masculino , Pobreza , Reproducibilidad de los Resultados , Estados Unidos
4.
J Res Adolesc ; 27(2): 436-451, 2017 06.
Artículo en Inglés | MEDLINE | ID: mdl-28876519

RESUMEN

Many early adolescents experience peer victimization, but little research has examined how they respond to aggression by peers. Thus, in a large sample of early adolescents (N = 648; M age = 12.96; SD = 0.30; 52.0% female), we examined (1) the associations between peer-reported victimization and self-reported responses to peer provocation, and (2) whether these associations were moderated by peer-reported aggression. In particular, we predicted that the reported use of assertion, a strategy generally viewed as socially skillful, would be associated with less victimization, but only for youth low on peer-reported aggression. Results were consistent with this hypothesis. Moreover, seeking adult intervention was associated with greater victimization for youth high on peer-reported aggression. Implications for research and practice are discussed.


Asunto(s)
Asertividad , Acoso Escolar/psicología , Víctimas de Crimen/psicología , Adolescente , Niño , Estudios de Cohortes , Estudios Transversales , Femenino , Humanos , Relaciones Interpersonales , Estudios Longitudinales , Masculino , Grupo Paritario , Autoinforme , Distribución por Sexo
5.
J Trauma Stress ; 29(6): 491-499, 2016 12.
Artículo en Inglés | MEDLINE | ID: mdl-27859679

RESUMEN

Young children can experience violence directly or indirectly in the home, with some children exposed to multiple forms of violence. These polyvictims often experience violence that is severe, chronic, and multifaceted. The current study used latent class analysis to identify and examine the pattern of profiles of exposure to family violence (i.e., violence directed towards the child and between caregivers) among a sample of 474 children ages 3-6 year who were drawn from the Multidimensional Assessment of Preschoolers Study (Wakschlag et al., 2014). The data yielded 3 classes: a polyvictimized class (n = 72; 15.2%) with high probability of exposure to all forms of violence, a harsh parenting class (n = 235; 49.5%), distinguished mainly by child-directed physical discipline in the absence of more severe forms of violence, and a low-exposure class (n = 167; 35.2%). Classes were differentiated by contextual factors, maternal characteristics, and mother-reported and observational indicators of parenting and child functioning with most effect sizes between medium and large. These findings add to emerging evidence linking polyvictimization to impaired caregiving and adverse psychological outcomes for children and offer important insight for prevention and intervention for this vulnerable population.


Asunto(s)
Violencia Doméstica/psicología , Exposición a la Violencia/psicología , Padres/psicología , Trastornos por Estrés Postraumático/prevención & control , Cuidadores/psicología , Niño , Trastornos de la Conducta Infantil/psicología , Preescolar , Estudios de Cohortes , Violencia Doméstica/clasificación , Femenino , Humanos , Masculino , Relaciones Madre-Hijo/psicología , Factores de Riesgo , Gestión de Riesgos , Trastornos por Estrés Postraumático/etiología , Encuestas y Cuestionarios
6.
Soc Sci Res ; 53: 364-74, 2015 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-26188460

RESUMEN

This study investigated the longitudinal effects of family structure changes and housing instability in adolescence on functioning in the transition to adulthood. A model examined the influence of household composition changes and mobility in context of ethnic differences and sociodemographic risks. Data from the National Longitudinal Study of Adolescent Health measured household and residential changes over a 12-month period among a nationally representative sample of adolescents. Assessments in young adulthood measured rates of depression, criminal activity, and smoking. Findings suggested housing mobility in adolescence predicted poorer functioning across outcomes in young adulthood, and youth living in multigenerational homes exhibited greater likelihood to be arrested than adolescents in single-generation homes. However, neither family structure changes nor its interaction with residential instability or ethnicity related to young adult outcomes. Findings emphasized the unique influence of housing mobility in the context of dynamic household compositions.


Asunto(s)
Crimen , Depresión/etiología , Composición Familiar , Vivienda , Fumar , Adolescente , Anomia (Social) , Etnicidad , Familia , Femenino , Humanos , Estudios Longitudinales , Masculino , Dinámica Poblacional , Características de la Residencia , Factores Socioeconómicos
7.
Dev Psychopathol ; 26(4 Pt 1): 1161-79, 2014 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-24713426

RESUMEN

This study examined whether a family-based preventive intervention for inner-city children entering the first grade could alter the developmental course of attention-deficit/hyperactivity disorder (ADHD) symptoms. Participants were 424 families randomly selected and randomly assigned to a control condition (n = 192) or Schools and Families Educating Children (SAFE) Children (n = 232). SAFE Children combined family-focused prevention with academic tutoring to address multiple developmental-ecological needs. A booster intervention provided in the 4th grade to randomly assigned children in the initial intervention (n =101) evaluated the potential of increasing preventive effects. Follow-up occurred over 5 years with parents and teachers reporting on attention problems. Growth mixture models identified multiple developmental trajectories of ADHD symptoms. The initial phase of intervention placed children on more positive developmental trajectories for impulsivity and hyperactivity, demonstrating the potential for ADHD prevention in at-risk youth, but the SAFE Children booster had no additional effect on trajectory or change in ADHD indicators.


Asunto(s)
Trastorno por Déficit de Atención con Hiperactividad/prevención & control , Terapia Familiar/métodos , Trastorno por Déficit de Atención con Hiperactividad/etiología , Trastorno por Déficit de Atención con Hiperactividad/psicología , Niño , Conducta Infantil/psicología , Familia/psicología , Femenino , Humanos , Masculino , Áreas de Pobreza , Factores de Riesgo
8.
Prev Sci ; 15(4): 437-47, 2014 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-23494404

RESUMEN

Predictive epidemiology is an embryonic field that involves developing informative signatures for disorder and tracking them using surveillance methods. Through such efforts assistance can be provided to the planning and implementation of preventive interventions. Believing that certain minor crimes indicative of gang activity are informative signatures for the emergence of serious youth violence in communities, in this study we aim to predict outbreaks of violence in neighborhoods from pre-existing levels and changes in reports of minor offenses. We develop a prediction equation that uses publicly available neighborhood-level data on disorderly conduct, vandalism, and weapons violations to predict neighborhoods likely to have increases in serious violent crime. Data for this study were taken from the Chicago Police Department ClearMap reporting system, which provided data on index and non-index crimes for each of the 844 Chicago census tracts. Data were available in three month segments for a single year (fall 2009, winter, spring, and summer 2010). Predicted change in aggravated battery and overall violent crime correlated significantly with actual change. The model was evaluated by comparing alternative models using randomly selected training and test samples, producing favorable results with reference to overfitting, seasonal variation, and spatial autocorrelation. A prediction equation based on winter and spring levels of the predictors had area under the curve ranging from .65 to .71 for aggravated battery, and .58 to .69 for overall violent crime. We discuss future development of such a model and its potential usefulness in violence prevention and community policing.


Asunto(s)
Modelos Teóricos , Violencia , Adolescente , Predicción , Humanos
9.
J Clin Psychol ; 70(7): 658-72, 2014 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-24382705

RESUMEN

OBJECTIVE: For ethnic minority families, the bridging of clinician-client differences is essential to their engagement in treatment. The Culturally Enhanced Video Feedback Engagement (CEVE) intervention aims to enhance client engagement through fostering clinician-client shared cultural understanding. The present study tested the effectiveness of the CEVE on client-rated clinician cultural competence and therapeutic alliance. METHOD: Nineteen ethnic minority families with children aged 3-6 years were randomized to the CEVE (n = 9) or treatment as usual (n = 10) at an outpatient clinic. RESULTS: Results from linear mixed effects regression models indicated a significant effect of the CEVE on intercept, suggesting that clinician cultural competence and therapeutic alliance were significantly higher in the CEVE condition. No effect was found for clinician growth in skills. CONCLUSIONS: The results indicate that the CEVE enhances client treatment engagement via clinician cultural competence and clinician-client alliance, suggesting its promise as a clinical engagement tool, particularly for treatments serving ethnic minority families.


Asunto(s)
Déficit de la Atención y Trastornos de Conducta Disruptiva/terapia , Comprensión , Competencia Cultural/psicología , Terapia Familiar/normas , Grupos Minoritarios/psicología , Relaciones Profesional-Paciente , Adulto , Niño , Preescolar , Etnicidad/psicología , Terapia Familiar/métodos , Femenino , Humanos , Masculino , Proyectos Piloto , Resultado del Tratamiento
10.
J Cogn Psychother ; 28(1): 3-19, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-24944436

RESUMEN

Among adolescents there is evidence that cognitive change partially mediates the effect of cognitive behavioral therapy (CBT) on depression outcome. However, prior studies have been limited by small samples, narrow measures of cognition, and failure to compare cognitive change following CBT to cognitive change following antidepressant medication. This study examined whether change in four cognitive constructs (cognitive distortions, cognitive avoidance, positive outlook, and solution-focused thinking) mediated change in depression severity in a sample of 291 adolescents who participated in the Treatment for Adolescents with Depression Study (TADS). TADS assessed the effects of CBT, fluoxetine, and their combination on depression severity. All three treatments were associated with change in the cognitive constructs and combination treatment produced the greatest change. Furthermore, change in the cognitive constructs partially mediated change in depression severity within all three treatments. Results implicated positive outlook as the construct most associated with change in depression severity over 36 weeks.

11.
J Exp Criminol ; 10(2): 179-206, 2014 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-25386111

RESUMEN

OBJECTIVES: To conduct a meta-analytic review of selective and indicated mentoring interventions for effects for youth at risk on delinquency and key associated outcomes (aggression, drug use, academic functioning). We also undertook the first systematic evaluation of intervention implementation features and organization and tested for effects of theorized key processes of mentor program effects. METHODS: Campbell Collaboration review inclusion criteria and procedures were used to search and evaluate the literature. Criteria included a sample defined as at-risk for delinquency due to individual behavior such as aggression or conduct problems or environmental characteristics such as residence in high-crime community. Studies were required to be random assignment or strong quasi-experimental design. Of 163 identified studies published 1970 - 2011, 46 met criteria for inclusion. RESULTS: Mean effects sizes were significant and positive for each outcome category (ranging form d =.11 for Academic Achievement to d = .29 for Aggression). Heterogeneity in effect sizes was noted for all four outcomes. Stronger effects resulted when mentor motivation was professional development but not by other implementation features. Significant improvements in effects were found when advocacy and emotional support mentoring processes were emphasized. CONCLUSIONS: This popular approach has significant impact on delinquency and associated outcomes for youth at-risk for delinquency. While evidencing some features may relate to effects, the body of literature is remarkably lacking in details about specific program features and procedures. This persistent state of limited reporting seriously impedes understanding about how mentoring is beneficial and ability to maximize its utility.

12.
Prev Sci ; 14(2): 121-33, 2013 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-21274627

RESUMEN

This article reviews the literature on school-based universal violence prevention programs to illustrate key methodological challenges for investigating subgroup differences in prevention effects. The variety of potential moderating factors examined within this literature is discussed within the context of a social-ecological model. Our review of this literature identified the following methodological issues: the need for a clear a priori theoretical basis for selecting potential moderators, inflated Type I error rates that result from large numbers of comparisons, the absence of explicit tests of moderation, interpretive issues arising from a restricted range on moderator variables, the failure to report effect size estimates, the presence of potential confounding factors, and the importance of examining factors that might operate at multiple ecological levels. These points are illustrated using examples of studies, primarily within youth violence prevention research, that have identified factors within the individual, school, and community that moderate the outcomes of preventive interventions. We conclude with general recommendations for future work. These include the benefits of using the social-ecological model to provide a basis for moving from exploratory to more theory-driven confirmatory models of subgroup differences, the potential merits of qualitative research designed to identify factors that may influence the effectiveness of intervention efforts for specific subgroups of individuals, and the provision of effect size estimates and confidence intervals for effect sizes in prevention reports.


Asunto(s)
Servicios de Salud Escolar/organización & administración , Violencia/prevención & control , Adolescente , Familia , Humanos
13.
Am J Community Psychol ; 52(3-4): 324-32, 2013 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-24048812

RESUMEN

Research has shown variable conceptualizations of neighborhood, often inconsistent with administrative boundaries. The present investigation seeks to quantify the geographic area encompassed by citizens' reporting of crime. Two Chicago violence prevention organizations gathered near real-time citizen reports of crime and other precursors of violence in a south side community. Over the course of 6 months, 48 community residents participated in a weekly telephone survey about incidents occurring in their community, including crime, incivilities, and disorder. For each incident reported in the study community, respondents were asked to specify its location, whether it was witnessed or heard about, and if it occurred within one block of their residence. Incident locations were geocoded and used to compute distance from residence. Incident reporting radii were calculated for all types of incidents. Calculated distances of events reported within a block revealed discrepancies between resident perceptions and geographic apportionments. On average, incident reports spanned just over a half-mile geographic radius from respondents' residences. Reporting radii were greater for more violent incidents and shorter for incidents witnessed directly. There was no effect of age, gender, length of residence, or length of participation in the study on reporting radii. Descriptions of reporting radii and implications for crime prevention efforts and research are discussed.


Asunto(s)
Participación de la Comunidad/métodos , Crimen/prevención & control , Características de la Residencia , Adulto , Chicago , Participación de la Comunidad/estadística & datos numéricos , Crimen/estadística & datos numéricos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Violencia/prevención & control , Violencia/estadística & datos numéricos
14.
Am J Community Psychol ; 52(1-2): 106-14, 2013 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-23702790

RESUMEN

This study aimed to estimate the prevalence of inadequate housing that threaten out-of-home placement among families under investigation by child welfare. Data came from the National Survey of Child and Adolescent Well-Being, a nationally representative longitudinal survey of child welfare-involved families. Child protective services caseworkers as well as caregivers provided information on families whose child remained in the home after initial investigation (N = 3,867). Multilevel latent class analyses tested the presence of inadequately housed subgroups using 4 housing problem indicators at baseline. Logistic regressions assessed convergent and predictive validity. A two class latent solution best fit the data. Findings indicated that inadequate housing contributed to risk for out-of-home placement in approximately 16 % of intact families under investigation by child protective services. These families were 4 times more likely to need housing services 12 months later. Federal legislation emphasizes integration of social services as necessary to end homelessness. This study demonstrates overlap across public agencies. Enhanced coordination of child welfare and housing services facilitates interventions to prevent and mitigate homelessness.


Asunto(s)
Maltrato a los Niños/estadística & datos numéricos , Protección a la Infancia/estadística & datos numéricos , Vivienda/estadística & datos numéricos , Personas con Mala Vivienda/estadística & datos numéricos , Servicio Social/organización & administración , Adolescente , Niño , Preescolar , Humanos , Lactante , Modelos Logísticos , Análisis Multinivel , Política Pública , Factores de Riesgo , Muestreo , Estados Unidos
15.
J Child Adolesc Subst Abuse ; 21(1): 1-31, 2012 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-22844190

RESUMEN

A prospective multi-site study examined organizational climate and structure effects on the behavior and functioning of delinquent youth with and without co-occurring substance treated with an evidence-based treatment for serious antisocial behavior (i.e., Multisystemic Therapy). Participants were 1979 youth treated by 429 therapists across 45 provider organizations in North America. Results of Mixed Effects Regression Models showed some aspects of climate and structure had no effects, some had similar effects, and some had slightly differential and sometimes counter-intuitive effects on the outcomes of these youth. Implications are considered for research to increase the array and availability of effective treatments for youth with co-occurring substance use across service sectors.

16.
Child Dev ; 82(1): 146-61, 2011.
Artículo en Inglés | MEDLINE | ID: mdl-21291434

RESUMEN

This study examined parenting variables as protective factors to reduce the influence of school and peer risk factors on adolescents' aggression. Five waves of data spanning 3 years were collected from 5,581 students at 37 schools who began the 6th grade in 2001 or 2002. Class-level and perceived school norms supporting aggression, delinquent peer associations, parental support for fighting and support for nonviolence, and parental involvement were each associated with physical aggression across all waves. Each parenting variable moderated 1 or more risk factors, with the magnitude of many effects varying by gender and decreasing over time. Implications for the role parents may play in reducing the impact of school and peer risk factors for aggression are discussed.


Asunto(s)
Agresión/psicología , Delincuencia Juvenil/psicología , Responsabilidad Parental/psicología , Grupo Paritario , Valores Sociales , Socialización , Violencia/psicología , Niño , Trastornos de la Conducta Infantil/psicología , Crianza del Niño , Estudios de Cohortes , Comunicación , Humanos , Delincuencia Juvenil/prevención & control , Determinación de la Personalidad , Factores de Riesgo , Medio Social , Facilitación Social , Estados Unidos , Violencia/prevención & control
17.
J Adolesc ; 34(5): 965-76, 2011 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-21216455

RESUMEN

This study examined the levels and growth of specific and general normative beliefs about nonviolence (called norms for nonviolence). The sample consisted of 1,254 middle school students from four metropolitan areas who participated in the control condition of the Multisite Violence Prevention Project. We predicted that the association and endorsement of specific and general norms for nonviolence would strengthen over time, levels and growth of norms for nonviolence would be moderated by gender and ethnicity, and norms for nonviolence would be related to youths' behaviors. Linear mixed models found that levels and direction of growth in specific and general norms varied as a function of gender, age, and ethnicity, providing partial support for our hypotheses. Specific and general norms for nonviolence were also consistently positively related to students' social skills and negatively related to students' aggressive behavior. Implications for understanding adolescent development are discussed.


Asunto(s)
Agresión , Conducta Social , Estudiantes/psicología , Adolescente , Ciudades , Femenino , Humanos , Masculino , Modelos Estadísticos , Grupo Paritario , Encuestas y Cuestionarios , Estados Unidos
18.
Am J Community Psychol ; 47(3-4): 277-86, 2011 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-21181552

RESUMEN

This study informs community science, and seeks to narrow the research-to-practice gap, by examining how the interpersonal networks within a setting influence individuals' use of interventions. More specifically, it explores the role of two network mechanisms-cohesion and structural similarity-in urban elementary school teachers' use of interventions designed to improve academic and behavioral outcomes for students. Lagged regression models examine how position in advice giving networks influenced weekly use of the daily report card and peer assisted learning by kindergarten through fourth grade teachers in three schools. Results indicate that intervention use spreads among teachers with similar patterns of advice-giving relationships (i.e., via structural similarity), rather than from teachers who are sources of advice (i.e., via cohesion). These results are consistent with findings in other settings, and suggest that researchers wishing to increase the use of an intervention should select change agents based on their patterns of their relationships, rather than on their direct connections.


Asunto(s)
Redes Comunitarias , Difusión de Innovaciones , Chicago , Docentes , Familia , Femenino , Humanos , Aprendizaje , Masculino , Análisis de Regresión , Población Urbana
19.
Bipolar Disord ; 12(6): 593-605, 2010 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-20868458

RESUMEN

OBJECTIVE: To determine the relative effects of risperidone and divalproex in pediatric mania. METHODS: This is a double-blind, randomized, outpatient clinical trial with 66 children and adolescents (mean age= 10.9 ± 3.3 years; age range= 8-18 years) with mania who were randomly assigned to either risperidone (0.5-2 mg/day, n= 33) or divalproex (60-120 µg/mL, n= 33) for a six-week period. Measures included the Young Mania Rating Scale (YMRS) and Child Depression Rating Scale-Revised (CDRS-R). RESULTS: Mixed-effects regression models, with interaction between time and the active drug as predictors, found that the risperidone group had more rapid improvement than the divalproex group (p < 0.05), although final scores did not differ significantly between groups. Mixed models using only those subjects who completed the six-week study found similar results. The response rate on YMRS was 78.1% for risperidone and 45.5% for divalproex (p < 0.01). The remission rate for risperidone was 62.5%, compared with 33.3% for divalproex (p < 0.05). Improvement on the CDRS-R was significantly higher for the risperidone group relative to the divalproex group (p < 0.05). There were no significant differences between groups in safety, but subject retention was significantly higher at study endpoint in the risperidone group (p < 0.01). Dropout rate was 24% in the risperidone group and 48% in the divalproex group, with increased irritability being the most common reason for dropout in the latter. There was no significant weight gain in either group. CONCLUSION: Results suggest that risperidone was associated with more rapid improvement and greater reduction in manic symptoms compared to divalproex. Although the results suggest that both drugs are safe, risperidone's lower attrition rate and lower rate of adverse events may suggest better toleration. Clinical trials with larger samples are required to confirm these preliminary findings.


Asunto(s)
Antimaníacos/uso terapéutico , Antipsicóticos/uso terapéutico , Trastorno Bipolar/tratamiento farmacológico , Risperidona/uso terapéutico , Ácido Valproico/uso terapéutico , Adolescente , Antimaníacos/efectos adversos , Antipsicóticos/efectos adversos , Niño , Método Doble Ciego , Femenino , Humanos , Masculino , Pacientes Ambulatorios , Risperidona/efectos adversos , Resultado del Tratamiento , Ácido Valproico/efectos adversos
20.
J Clin Child Adolesc Psychol ; 39(6): 800-13, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-21058127

RESUMEN

This study examined the direct effects of beliefs about aggression and nonviolence on physical aggression and their role as protective factors that buffer adolescents from key risk factors in the peer, school, and parenting domains. Multilevel analyses were conducted on data from 5,581 adolescents representing two cohorts from 37 schools in four communities collected at the beginning and end of the sixth grade and at the end of the following 2 school years. Individual norms for aggression at Wave 1 moderated relations of delinquent peer associations and parental support for fighting with physical aggression. Self-efficacy for nonviolence at Wave 1 moderated relations of school risk, delinquent peer associations and parental support for fighting with physical aggression. There was clearer evidence for protective effects for self-efficacy for nonviolence for girls than for boys.


Asunto(s)
Agresión/psicología , Padres , Grupo Paritario , Autoeficacia , Identificación Social , Apoyo Social , Estudiantes/psicología , Adolescente , Niño , Femenino , Estudios de Seguimiento , Humanos , Relaciones Interpersonales , Masculino , Análisis Multinivel , Factores de Riesgo , Instituciones Académicas , Factores Sexuales , Medio Social , Encuestas y Cuestionarios , Virginia
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