Detalles de la búsqueda
1.
Performance and Sensitivity of [99mTc]Tc-sestamibi Compared with Positron Emission Tomography Radiotracers to Measure P-glycoprotein Function in the Kidneys and Liver.
Mol Pharm
; 21(2): 932-943, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38225758
2.
Positron Emission Tomography-Based Pharmacokinetic Analysis To Assess Renal Transporter-Mediated Drug-Drug Interactions of Antimicrobial Drugs.
Antimicrob Agents Chemother
; 67(3): e0149322, 2023 03 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36786609
3.
Use of PET Imaging to Assess the Efficacy of Thiethylperazine to Stimulate Cerebral MRP1 Transport Activity in Wild-Type and APP/PS1-21 Mice.
Int J Mol Sci
; 23(12)2022 Jun 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35742960
4.
Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.
Pharm Res
; 38(1): 127-140, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33559045
5.
Measurement of Hepatic ABCB1 and ABCG2 Transport Activity with [11C]Tariquidar and PET in Humans and Mice.
Mol Pharm
; 17(1): 316-326, 2020 01 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31790256
6.
[11C]metoclopramide is a sensitive radiotracer to measure moderate decreases in P-glycoprotein function at the blood-brain barrier.
J Cereb Blood Flow Metab
; 44(1): 142-152, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37728771
7.
Influence of P-glycoprotein on pulmonary disposition of the model substrate [11C]metoclopramide assessed by PET imaging in rats.
Eur J Pharm Sci
; 183: 106404, 2023 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36773747
8.
Effect of budesonide on pulmonary activity of multidrug resistance-associated protein 1 assessed with PET imaging in rats.
Eur J Pharm Sci
; 184: 106414, 2023 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36858275
9.
Nuclear medicine imaging methods as novel tools in the assessment of pulmonary drug disposition.
Expert Opin Drug Deliv
; 19(12): 1561-1575, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36255136
10.
PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats.
J Control Release
; 342: 44-52, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34971693
11.
Pharmacokinetic Imaging Using 99mTc-Mebrofenin to Untangle the Pattern of Hepatocyte Transporter Disruptions Induced by Endotoxemia in Rats.
Pharmaceuticals (Basel)
; 15(4)2022 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35455390
12.
Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats.
J Control Release
; 349: 109-117, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35798092
13.
Repurposing 99mTc-Mebrofenin as a Probe for Molecular Imaging of Hepatocyte Transporters.
J Nucl Med
; 62(8): 1043-1047, 2021 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33674399
14.
Imaging-Based Characterization of a Slco2b1(-/-) Mouse Model Using [11C]Erlotinib and [99mTc]Mebrofenin as Probe Substrates.
Pharmaceutics
; 13(6)2021 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-34205780
15.
Influence of ABC transporters on the excretion of ciprofloxacin assessed with PET imaging in mice.
Eur J Pharm Sci
; 163: 105854, 2021 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33865975
16.
Assessing the Functional Redundancy between P-gp and BCRP in Controlling the Brain Distribution and Biliary Excretion of Dual Substrates with PET Imaging in Mice.
Pharmaceutics
; 13(8)2021 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34452247
17.
Complete inhibition of ABCB1 and ABCG2 at the blood-brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib.
J Cereb Blood Flow Metab
; 41(7): 1634-1646, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33081568
18.
Use of imaging to assess the activity of hepatic transporters.
Expert Opin Drug Metab Toxicol
; 16(2): 149-164, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31951754
19.
Validation of Pharmacological Protocols for Targeted Inhibition of Canalicular MRP2 Activity in Hepatocytes Using [99mTc]mebrofenin Imaging in Rats.
Pharmaceutics
; 12(6)2020 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32471244
20.
Assessing the Activity of Multidrug Resistance-Associated Protein 1 at the Lung Epithelial Barrier.
J Nucl Med
; 61(11): 1650-1657, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32284394