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1.
Opt Lett ; 43(16): 4029-4032, 2018 Aug 15.
Artículo en Inglés | MEDLINE | ID: mdl-30106944

RESUMEN

A noninvasive method for characterizing Si/Mo thin-film stack thickness and its complex transfer function using common-path optical coherence tomography is proposed, analyzed, and experimentally demonstrated. A laser-produced plasma (LPP)-based extreme ultraviolet (EUV) source was excited by a four-stage nanosecond Yb:fiber laser amplifier with a pulse energy of 1.01 mJ. The tabletop LPP EUV source was compact and stable for generating the EUV interference fringes. The measured complex transfer function of the Si/Mo stack was verified near the pristine 13.5-nm wavelength range.

2.
Opt Lett ; 41(14): 3217-20, 2016 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-27420499

RESUMEN

Efficient glass-clad crystal fiber (CF) lasers were demonstrated using a Ti:sapphire crystalline core as the gain medium. With a core diameter of 18 µm, the laser diode (LD) pump source can be effectively coupled and guided throughout the crystal fiber for a low threshold and high slope efficiency laser operation. The advantage of high heat dissipation efficiency of the fiber structure can be derived from the low core temperature rising measurement (i.e., 17 K/W) with passive cooling. At an output transmittance of 23%, the lowest absorbed threshold of 118.2 mW and highest slope efficiency of 29.6% were achieved, with linear laser polarization.

3.
Opt Lett ; 40(23): 5594-7, 2015 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-26625059

RESUMEN

High-brightness near-infrared broadband amplified spontaneous emission (ASE) was generated by glass-clad Ti:sapphire crystal fibers, which were developed using the co-drawing laser-heated pedestal growth method. As much as 29.2 mW of ASE power was generated using 520 nm laser diodes as the excitation source on an a-cut, 18 µm core-diameter Ti:sapphire crystal fiber (CF). The 3 dB bandwidth was 163.8 nm, and the radiance was 53.94 W·mm(-2) sr(-1). The propagation loss of the glass-clad sapphire CF measured using the cutback method was 0.017 cm(-1) at 780 nm. For single-mode applications, more than 100 µW of power was coupled into a SM600 single-mode fiber.

4.
Opt Express ; 22(5): 5675-83, 2014 Mar 10.
Artículo en Inglés | MEDLINE | ID: mdl-24663908

RESUMEN

A non-invasive method for measuring the refractive index, extinction coefficient and film thickness of absorptive thin films using spectral-domain optical coherent tomography is proposed, analyzed and experimentally demonstrated. Such an optical system employing a normal-incident beam of light exhibits a high spatial resolution. There are no mechanical moving parts involved for the measurement except the transversal scanning module for the measurement at various transversal locations. The method was experimentally demonstrated on two absorptive thin-film samples coated on transparent glass substrates. The refractive index and extinction coefficient spectra from 510 to 580 nm wavelength range and film thickness were simultaneously measured. The results are presented and discussed.

5.
Opt Express ; 19(8): 7153-60, 2011 Apr 11.
Artículo en Inglés | MEDLINE | ID: mdl-21503029

RESUMEN

Shaping the ferroelectric domains as waveguide, grating, lens, and prism are key to the successful penetration of periodically-poled ferroelectrics on various wavelength conversion applications. The complicated structures are, however, difficult to be fully characterized, especially the unexpected index contrast at the anti-parallel domain boundaries are typical in the order of 10(-4) or less. An ultrahigh resolution optical coherence tomography was employed to fully characterize the domain boundary and structure properties of a periodically-poled lithium niobate (PPLN) waveguide with an axial resolution of 0.68 µm, an transversal resolution of 3.2 µm, and an index contrast sensitivity of 4x10(-7). The anti-parallel domain uniformity can clearly be seen non-invasively. Dispersion of the ferroelectric material was also obtained from 500 to 750 nm.

6.
Biomed Opt Express ; 12(5): 2670-2683, 2021 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-34123496

RESUMEN

A crystalline-fiber-based Mirau-type full-field optical coherence tomography (FF-OCT) system utilizing two partially coherent illumination modes is presented. Using a diode-pumped Ti:sapphire crystalline fiber with a high numerical aperture, spatially-incoherent broadband emission can be generated with high radiance. With two modes of different spatial coherence settings, either deeper penetration depth or higher B-scan rate can be achieved. In a wide-field illumination mode, the system functions like FF-OCT with partially coherent illumination to improve the penetration depth. In a strip-field illumination mode, a compressed field is generated on the sample, and a low-speckle B-scan can be acquired by compounding pixel lines within.

7.
J Biomed Opt ; 26(2)2021 02.
Artículo en Inglés | MEDLINE | ID: mdl-33624460

RESUMEN

SIGNIFICANCE: Melanocytic nevi represent the most common dermal melanocytic lesions in humans. Nevus is typically diagnosed clinically with the naked eye or with dermoscopy. However, it is essential to identify the type of nevus by invasive biopsy for histopathological examination. The use of noninvasive imaging tools can be used to evaluate the types of nevi to reduce unnecessary excisions of benign entities. AIM: To evaluate the feasibility of using en face and cross-sectional full-field optical coherence tomography (FF-OCT) in differentiation of melanocytic nevi that can facilitate the reduction of unnecessary excisions of benign entities. APPROACH: Dual-mode Mirau-type FF-OCT for cross-sectional imaging (B-scan) and en face imaging were used to distinguish the types of nevi. RESULTS: Although the B-scan reveals the distribution of melanosomes, users can set a specific depth of the en face image to explore the morphology of surrounding skin cells instantly. According to the locations of nevus nests, the different types of nevi, including junction nevus and compound nevus, can be identified using this dual-mode FF-OCT system. CONCLUSIONS: Combining B-scan and en face imaging in vivo FF-OCT enables the examination and navigation of skin tissues in real time and in three dimensions.


Asunto(s)
Melanoma , Nevo Pigmentado , Neoplasias Cutáneas , Diferenciación Celular , Humanos , Nevo Pigmentado/diagnóstico por imagen , Neoplasias Cutáneas/diagnóstico por imagen , Tomografía de Coherencia Óptica
8.
Biomed Opt Express ; 5(9): 3001-10, 2014 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-25401013

RESUMEN

With a Gaussian-like broadband light source from high brightness Ce(3+):YAG single-clad crystal fiber, a full-field optical coherence tomography using a home-designed Mirau objective realized high quality images of in vivo and excised skin tissues. With a 40 × silicone-oil-immersion Mirau objective, the achieved spatial resolutions in axial and lateral directions were 0.9 and 0.51 µm, respectively. Such a high spatial resolution enables the separation of lamellar structure of the full epidermis in both the cross-sectional and en face planes. The number of layers of stratum corneum and its thickness were quantitatively measured. This label free and non-invasive optical probe could be useful for evaluating the water barrier of skin tissue in clinics. As a preliminary in vivo experiment, the blood vessel in dermis was also observed, and the flowing of the red blood cells and location of the melanocyte were traced.

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