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1.
Rep Prog Phys ; 87(3)2024 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-38241725

RESUMEN

For decades, frustrated quantum magnets have been a seed for scientific progress and innovation in condensed matter. As much as the numerical tools for low-dimensional quantum magnetism have thrived and improved in recent years due to breakthroughs inspired by quantum information and quantum computation, higher-dimensional quantum magnetism can be considered as the final frontier, where strong quantum entanglement, multiple ordering channels, and manifold ways of paramagnetism culminate. At the same time, efforts in crystal synthesis have induced a significant increase in the number of tangible frustrated magnets which are generically three-dimensional in nature, creating an urgent need for quantitative theoretical modeling. We review the pseudo-fermion (PF) and pseudo-Majorana (PM) functional renormalization group (FRG) and their specific ability to address higher-dimensional frustrated quantum magnetism. First developed more than a decade ago, the PFFRG interprets a Heisenberg model Hamiltonian in terms of Abrikosov pseudofermions, which is then treated in a diagrammatic resummation scheme formulated as a renormalization group flow ofm-particle pseudofermion vertices. The article reviews the state of the art of PFFRG and PMFRG and discusses their application to exemplary domains of frustrated magnetism, but most importantly, it makes the algorithmic and implementation details of these methods accessible to everyone. By thus lowering the entry barrier to their application, we hope that this review will contribute towards establishing PFFRG and PMFRG as the numerical methods for addressing frustrated quantum magnetism in higher spatial dimensions.

2.
Endocr Pract ; 2024 Jul 04.
Artículo en Inglés | MEDLINE | ID: mdl-38969009

RESUMEN

OBJECTIVE: The objectives of this study were to evaluate the stratification of people with diabetes mellitus (DM) based on the International Diabetes Federation-Diabetes and Ramadan 2021 risk calculator into different risk categories and assess their intentions to fast and outcomes of fasting during the holy month of Ramadan. METHODS: This was a 3-month prospective study that was performed from February 9, 2023, to May 6, 2023 (6 weeks before Ramadan until 6 weeks after Ramadan), at a tertiary care hospital in Pakistan. Data regarding glycemic control, characteristics and complications of diabetes, comorbidities, and the various factors that influence fasting were gathered from patients of either sex aged 18 to 80 years with any type of diabetes. The International Diabetes Federation-Diabetes and Ramadan 2021 risk calculation and recommendation were made accordingly for each patient. RESULTS: This study comprised of 460 participants with DM, with 174 males (37.8%) and 286 females (62.2%). The risk categorization showed that 209 (45.4%), 107 (23.3%), and 144 (31.3%) of the participants were in the low-, moderate-, and high-risk categories, respectively. Of the 144 high-risk patients who fasted, 57.9% experienced hypoglycemia (P <.0001). The recommendation of fasting showed statistically significant differences with risk categories, intention to fast, hypoglycemia, type of DM, duration of DM, level of glycemic control, and days of fasting (P <.001). CONCLUSION: A statistically significant number of participants in the high-risk group who fasted experienced complications. This reiterates the importance of rigorous adherence to the medical recommendations.

3.
Phys Rev Lett ; 130(19): 196601, 2023 May 12.
Artículo en Inglés | MEDLINE | ID: mdl-37243662

RESUMEN

Fracton phases are a particularly exotic type of quantum spin liquids where the elementary quasiparticles are intrinsically immobile. These phases may be described by unconventional gauge theories known as tensor or multipolar gauge theories, characteristic for so-called type-I or type-II fracton phases, respectively. Both variants have been associated with distinctive singular patterns in the spin structure factor, such as multifold pinch points for type-I and quadratic pinch points for type-II fracton phases. Here, we assess the impact of quantum fluctuations on these patterns by numerically investigating the spin S=1/2 quantum version of a classical spin model on the octahedral lattice featuring exact realizations of multifold and quadratic pinch points, as well as an unusual pinch line singularity. Based on large scale pseudofermion and pseudo-Majorana functional renormalization group calculations, we take the intactness of these spectroscopic signatures as a measure for the stability of the corresponding fracton phases. We find that in all three cases, quantum fluctuations significantly modify the shape of pinch points or lines by smearing them out and shifting signal away from the singularities in contrast to effects of pure thermal fluctuations. This indicates possible fragility of these phases and allows us to identify characteristic fingerprints of their remnants.

4.
BMC Genomics ; 23(1): 43, 2022 Jan 10.
Artículo en Inglés | MEDLINE | ID: mdl-35012465

RESUMEN

BACKGROUND: Miscanthus, which is a leading dedicated-energy grass in Europe and in parts of Asia, is expected to play a key role in the development of the future bioeconomy. However, due to its complex genetic background, it is difficult to investigate phylogenetic relationships in this genus. Here, we investigated 50 Miscanthus germplasms: 1 female parent (M. lutarioriparius), 30 candidate male parents (M. lutarioriparius, M. sinensis, and M. sacchariflorus), and 19 offspring. We used high-throughput Specific-Locus Amplified Fragment sequencing (SLAF-seq) to identify informative single nucleotide polymorphisms (SNPs) in all germplasms. RESULTS: We identified 257,889 SLAF tags, of which 87,162 were polymorphic. Each tag was 264-364 bp long. The obtained 724,773 population SNPs were used to investigate genetic relationships within three species of Miscanthus. We constructed a phylogenetic tree of the 50 germplasms using the obtained SNPs and grouped them into two clades: one clade comprised of M. sinensis alone and the other one included the offspring, M. lutarioriparius, and M. sacchariflorus. Genetic cluster analysis had revealed that M. lutarioriparius germplasm C3 was the most likely male parent of the offspring. CONCLUSIONS: As a high-throughput sequencing method, SLAF-seq can be used to identify informative SNPs in Miscanthus germplasms and to rapidly characterize genetic relationships within this genus. Our results will support the development of breeding programs with the focus on utilizing Miscanthus cultivars with elite biomass- or fiber-production potential for the developing bioeconomy.


Asunto(s)
Poaceae , Polimorfismo de Nucleótido Simple , Asia , Secuenciación de Nucleótidos de Alto Rendimiento , Filogenia , Poaceae/genética
5.
Sensors (Basel) ; 22(12)2022 Jun 11.
Artículo en Inglés | MEDLINE | ID: mdl-35746213

RESUMEN

Globally, the surge in disease and urgency in maintaining social distancing has reawakened the use of telemedicine/telehealth. Amid the global health crisis, the world adopted the culture of online consultancy. Thus, there is a need to revamp the conventional model of the telemedicine system as per the current challenges and requirements. Security and privacy of data are main aspects to be considered in this era. Data-driven organizations also require compliance with regulatory bodies, such as HIPAA, PHI, and GDPR. These regulatory compliance bodies must ensure user data privacy by implementing necessary security measures. Patients and doctors are now connected to the cloud to access medical records, e.g., voice recordings of clinical sessions. Voice data reside in the cloud and can be compromised. While searching voice data, a patient's critical data can be leaked, exposed to cloud service providers, and spoofed by hackers. Secure, searchable encryption is a requirement for telemedicine systems for secure voice and phoneme searching. This research proposes the secure searching of phonemes from audio recordings using fully homomorphic encryption over the cloud. It utilizes IBM's homomorphic encryption library (HElib) and achieves indistinguishability. Testing and implementation were done on audio datasets of different sizes while varying the security parameters. The analysis includes a thorough security analysis along with leakage profiling. The proposed scheme achieved higher levels of security and privacy, especially when the security parameters increased. However, in use cases where higher levels of security were not desirous, one may rely on a reduction in the security parameters.


Asunto(s)
Privacidad , Telemedicina , Nube Computacional , Seguridad Computacional , Confidencialidad , Humanos
6.
Phys Rev Lett ; 127(17): 177001, 2021 Oct 22.
Artículo en Inglés | MEDLINE | ID: mdl-34739258

RESUMEN

The recent discovery of AV_{3}Sb_{5} (A=K,Rb,Cs) has uncovered an intriguing arena for exotic Fermi surface instabilities in a kagome metal. Among them, superconductivity is found in the vicinity of multiple van Hove singularities, exhibiting indications of unconventional pairing. We show that the sublattice interference mechanism is central to understanding the formation of superconductivity in a kagome metal. Starting from an appropriately chosen minimal tight-binding model with multiple van Hove singularities close to the Fermi level for AV_{3}Sb_{5}, we provide a random phase approximation analysis of superconducting instabilities. Nonlocal Coulomb repulsion, the sublattice profile of the van Hove bands, and the interaction strength turn out to be the crucial parameters to determine the preferred pairing symmetry. Implications for potentially topological surface states are discussed, along with a proposal for additional measurements to pin down the nature of superconductivity in AV_{3}Sb_{5}.

7.
Phys Rev Lett ; 127(15): 157204, 2021 Oct 08.
Artículo en Inglés | MEDLINE | ID: mdl-34677991

RESUMEN

Quantum spin liquids are exotic states of matter that form when strongly frustrated magnetic interactions induce a highly entangled quantum paramagnet far below the energy scale of the magnetic interactions. Three-dimensional cases are especially challenging due to the significant reduction of the influence of quantum fluctuations. Here, we report the magnetic characterization of K_{2}Ni_{2}(SO_{4})_{3} forming a three-dimensional network of Ni^{2+} spins. Using density functional theory calculations, we show that this network consists of two interconnected spin-1 trillium lattices. In the absence of a magnetic field, magnetization, specific heat, neutron scattering, and muon spin relaxation experiments demonstrate a highly correlated and dynamic state, coexisting with a peculiar, very small static component exhibiting a strongly renormalized moment. A magnetic field B≳4 T diminishes the ordered component and drives the system into a pure quantum spin liquid state. This shows that a system of interconnected S=1 trillium lattices exhibits a significantly elevated level of geometrical frustration.

8.
Molecules ; 26(15)2021 Jul 31.
Artículo en Inglés | MEDLINE | ID: mdl-34361812

RESUMEN

Metal oxide nanoparticles synthesized by the biological method represent the most recent research in nanotechnology. This study reports the rapid and ecofriendly approach for the synthesis of CeO2 nanoparticles mediated using the Abelmoschus esculentus extract. The medicinal plant extract acts as both a reducing and stabilizing agent. The characterization of CeO2 NPs was performed by scanning electron microscopy (SEM), X-ray diffraction (XRD), ultraviolet-visible spectroscopy (UV-Vis), and Fourier transform infrared spectroscopy (FTIR). The in vitro cytotoxicity of green synthesized CeO2 was assessed against cervical cancerous cells (HeLa). The exposure of CeO2 to HeLa cells at 10-125 µg/mL caused a loss in cellular viability against cervical cancerous cells in a dose-dependent manner. The antibacterial activity of the CeO2 was assessed against S. aureus and K. pneumonia. A significant improvement in wound-healing progression was observed when cerium oxide nanoparticles were incorporated into the chitosan hydrogel membrane as a wound dressing.


Asunto(s)
Abelmoschus/química , Antioxidantes/síntesis química , Extractos Vegetales/farmacología , Staphylococcus aureus/efectos de los fármacos , Antibacterianos/química , Antibacterianos/farmacología , Antiinfecciosos/química , Antiinfecciosos/farmacología , Antioxidantes/química , Antioxidantes/farmacología , Proliferación Celular/efectos de los fármacos , Cerio/química , Tecnología Química Verde/tendencias , Células HeLa , Humanos , Nanopartículas del Metal/química , Microscopía Electrónica de Rastreo , Extractos Vegetales/química , Espectroscopía Infrarroja por Transformada de Fourier , Staphylococcus aureus/patogenicidad , Cicatrización de Heridas/efectos de los fármacos
9.
Breast Cancer Res ; 16(2): R35, 2014.
Artículo en Inglés | MEDLINE | ID: mdl-24708745

RESUMEN

INTRODUCTION: Immunohistochemical Ki67 labelling index (Ki67 LI) reflects proliferative activity and is a potential prognostic/predictive marker of breast cancer. However, its clinical utility is hindered by the lack of standardized measurement methodologies. Besides tissue heterogeneity aspects, the key element of methodology remains accurate estimation of Ki67-stained/counterstained tumour cell profiles. We aimed to develop a methodology to ensure and improve accuracy of the digital image analysis (DIA) approach. METHODS: Tissue microarrays (one 1-mm spot per patient, n = 164) from invasive ductal breast carcinoma were stained for Ki67 and scanned. Criterion standard (Ki67-Count) was obtained by counting positive and negative tumour cell profiles using a stereology grid overlaid on a spot image. DIA was performed with Aperio Genie/Nuclear algorithms. A bias was estimated by ANOVA, correlation and regression analyses. Calibration steps of the DIA by adjusting the algorithm settings were performed: first, by subjective DIA quality assessment (DIA-1), and second, to compensate the bias established (DIA-2). Visual estimate (Ki67-VE) on the same images was performed by five pathologists independently. RESULTS: ANOVA revealed significant underestimation bias (P < 0.05) for DIA-0, DIA-1 and two pathologists' VE, while DIA-2, VE-median and three other VEs were within the same range. Regression analyses revealed best accuracy for the DIA-2 (R-square = 0.90) exceeding that of VE-median, individual VEs and other DIA settings. Bidirectional bias for the DIA-2 with overestimation at low, and underestimation at high ends of the scale was detected. Measurement error correction by inverse regression was applied to improve DIA-2-based prediction of the Ki67-Count, in particularfor the clinically relevant interval of Ki67-Count < 40%. Potential clinical impact of the prediction was tested by dichotomising the cases at the cut-off values of 10, 15, and 20%. Misclassification rate of 5-7% was achieved, compared to that of 11-18% for the VE-median-based prediction. CONCLUSIONS: Our experiments provide methodology to achieve accurate Ki67-LI estimation by DIA, based on proper validation, calibration, and measurement error correction procedures, guided by quantified bias from reference values obtained by stereology grid count. This basic validation step is an important prerequisite for high-throughput automated DIA applications to investigate tissue heterogeneity and clinical utility aspects of Ki67 and other immunohistochemistry (IHC) biomarkers.


Asunto(s)
Neoplasias de la Mama/metabolismo , Carcinoma Ductal de Mama/metabolismo , Procesamiento de Imagen Asistido por Computador/métodos , Inmunohistoquímica/métodos , Antígeno Ki-67/análisis , Algoritmos , Análisis de Varianza , Neoplasias de la Mama/diagnóstico , Carcinoma Ductal de Mama/diagnóstico , Proliferación Celular , Femenino , Humanos , Inmunohistoquímica/instrumentación , Modelos Lineales , Índice Mitótico , Pronóstico , Reproducibilidad de los Resultados , Sensibilidad y Especificidad , Análisis de Matrices Tisulares/métodos
10.
J Pak Med Assoc ; 64(12): 1339-42, 2014 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-25842573

RESUMEN

OBJECTIVE: To assess perceptions of medical students about the factors that may enhance motivation for learning through small group discussions. METHODS: The qualitative descriptive study was conducted in May, 2013, at Riphah International University, Islamabad, and comprised undergraduate medical students from the first to the fourth year who were given a questionnaire that sought their opinion about group characteristics, composition, expectations from the teachers, environment, additional tools and optimum time duration. The effects of granting extra marks for active participation, feedback and weightage of attendance in enhancing motivation in small group discussions were also explored. Common themes from within the responses were highlighted. RESULTS: Initially, 400 students were given the questionnaire, but complete responses were received from 290(72.5%). About the effective group size, 221(76.2%) suggested 12 or less students, while 153(52.75%) thought groups should be divided into subgroups according to the task, and 148(51.03%) were in favour of mixed gender composition of a group. A comfortable and air-conditioned environment was suggested as a motivating factor by 156(53.79%) students. Use of models, laptops and internet during the discussion was suggested by 97(33.44%) students, and 232(80%) suggested an hour or less as sufficient time. Grant of extra marks 209(72.06%), feedback 220(75.86%) and weightage of attendance 193(66.55%) were all considered positive motivating factors. Finally, 250(86.20%) were in favour of continuation of small group discussion as a learning tool. CONCLUSION: Most students thought a smaller size makes a small group discussion more effective, and that it should continue to be used as one of the learning modalities.


Asunto(s)
Educación de Pregrado en Medicina , Aprendizaje , Estudiantes de Medicina/psicología , Humanos , Motivación
11.
Plants (Basel) ; 13(13)2024 Jul 05.
Artículo en Inglés | MEDLINE | ID: mdl-38999706

RESUMEN

Using contaminated land to grow lignocellulosic crops can deliver biomass and, in the long term, improve soil quality. Biostimulants and microorganisms are nowadays an innovative approach to define appropriate phytomanagement strategies to promote plant growth and metal uptake. This study evaluated biostimulants and mycorrhizae application on biomass production and phytoextraction potential of four lignocellulosic crops grown under two metal-contaminated soils. Two greenhouse pot trials were setup to evaluate two annual species (sorghum, hemp) in Italy and two perennial ones (miscanthus, switchgrass) in China, under mycorrhizae (M), root (B2) and foliar (B1) biostimulants treatments, based on humic substances and protein hydrolysates, respectively, applied both alone and in combination (MB1, MB2). MB2 increased the shoot dry weight (DW) yield in hemp (1.9 times more), sorghum (3.6 times more) and miscanthus (tripled) with additional positive effects on sorghum and miscanthus Zn and Cd accumulation, respectively, but no effects on hemp metal accumulation. No treatment promoted switchgrass shoot DW, but M enhanced Cd and Cr shoot concentrations (+84%, 1.6 times more, respectively) and the phytoextraction efficiency. Root biostimulants and mycorrhizae were demonstrated to be more efficient inputs than foliar biostimulants to enhance plant development and productivity in order to design effective phytomanagement strategies in metal-contaminated soil.

12.
Nat Commun ; 15(1): 7191, 2024 Aug 21.
Artículo en Inglés | MEDLINE | ID: mdl-39168995

RESUMEN

Quantum spin liquids (QSLs) have become a key area of research in magnetism due to their remarkable properties, such as long-range entanglement, fractional excitations, and topologically protected phenomena. Recently, the search for QSLs has expanded into the three-dimensional world, despite the suppression of quantum fluctuations due to high dimensionality. A new candidate material, K2Ni2(SO4)3, belongs to the langbeinite family and consists of two interconnected trillium lattices. Although magnetically ordered, it exhibits a highly dynamical and correlated state. In this work, we combine inelastic neutron scattering measurements with density functional theory (DFT), pseudo-fermion functional renormalization group (PFFRG), and classical Monte Carlo (cMC) calculations to study the magnetic properties of K2Ni2(SO4)3, revealing a high level of agreement between experiment and theory. We further reveal the origin of the dynamical state in K2Ni2(SO4)3 to be centred around a magnetic network composed of tetrahedra on a trillium lattice.

13.
Environ Sci Pollut Res Int ; 30(46): 103339-103357, 2023 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-37688708

RESUMEN

Nowadays, business is not only a financial entity. The environmental impact of rapid business growth necessitates solutions. This study considers natural resource orchestration theory (ROT) to study the impact of the environment management control system (MCS) package and green intellectual capital (IC) on environmental performance through the mediating role of top management support (TMS) and the interaction role of green business strategies. This study employed partial least squares structural equation modeling to analyze 358 questionnaires. Simple sampling was used to collect data from Pakistan manufacturing firms. The results revealed that the environmental MCS package significantly influences environmental performance directly and through TMS mediation. Still, the green IC does not influence environmental performance directly or through mediation in selected industries of Pakistan. Furthermore, the interaction of TMS and green business strategies significantly determines environmental performance. This study suggests managers use the environmental MCS package, green IC, top management support, and green business strategies in decision-making to determine environmental performance of manufacturing firms in Pakistan even though green IC has no influence on environmental performance. This study used natural ROT to impart the managerial role along with bundling firms' resources and strategies (i.e., environmental MCS package, green IC, top management support, and green business strategies) which is ignored in the resource-based view.

14.
Carbohydr Polym ; 321: 121318, 2023 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-37739510

RESUMEN

The attention to polymer-based biomaterials, for instance, chitosan and its derivatives, as well as the techniques for using them in numerous scientific domains, is continuously rising. Chitosan is a decomposable naturally occurring polymeric material that is mostly obtained from seafood waste. Because of its special ecofriendly, biocompatible, non- toxic nature as well as antimicrobial properties, chitosan-based materials have received a lot of interest in the field of biomedical applications. The reactivity of chitosan is mainly because of the amino and hydroxyl groups in its composition, which makes it further fascinating for various uses, including biosensing, textile finishing, antimicrobial wound dressing, tissue engineering, bioimaging, gene, DNA and drug delivery and as a coating material for medical implants. This study is an overview of the different types of chitosan-based materials which now a days have been fabricated by applying different techniques and modifications that include etherification, esterification, crosslinking, graft copolymerization and o-acetylation etc. for hydroxyl groups' processes and acetylation, quaternization, Schiff's base reaction, and grafting for amino groups' reactions. Furthermore, this overview summarizes the literature from recent years related to the important applications of chitosan-based materials (i.e., thin films, nanocomposites or nanoparticles, sponges and hydrogels) in different biomedical applications.


Asunto(s)
Quitosano , Esterificación , Materiales Biocompatibles/farmacología , Acetilación , Vendajes , Polímeros
15.
Future Med Chem ; 15(7): 599-613, 2023 04.
Artículo en Inglés | MEDLINE | ID: mdl-37140092

RESUMEN

Aim: To develop an efficient and cost-effective antidiabetic agent. Methods: A simple and convenient Hantzsch synthetic strategy was used to prepare 4-adamantyl-(2-(arylidene)hydrazinyl)thiazoles. Results: Fifteen newly established structures of 4-adamantyl-(2-(arylidene)hydrazinyl)thiazoles were tested for their α-amylase, antiglycation and antioxidant activities. Almost all tested compounds showed excellent α-amylase inhibition. Compounds 3a and 3j exhibited the highest potency, with IC50 values of 16.34 ± 2.67 and 16.64 ± 1.12 µM, respectively. Compounds 3c and 3i exhibited comparable antiglycation potential with the standard, aminoguanidine. The antioxidant potential of compound 3g was found to be excellent, with an IC50 value of 28.19 ± 0.2563 µM. The binding interactions of compound 3a (binding energy = -8.833 kcal/mol) with human pancreatic α-amylase identified 3a as a potent α-amylase inhibitor. Conclusion: Enrichment of established structures with more electron-donating functionalities may assist/lead to the development of more potent antidiabetic drugs.


Diabetes is one of the major causes of death in the present era. To combat damaging processes associated with diabetes, called glycation and oxidation, we prepared a series of compounds called 4-adamantyl-(2-(arylidene)hydrazinyl)thiazoles. The established structures were tested for their antidiabetic potential. The compounds 4-adamantyl-(2-(4-chlorobenzylidene)hydrazinyl)thiazole and 4-adamantyl-(2-(2-chlorobenzylidene)hydrazinyl)thiazole showed the highest potency. The compounds 4-adamantyl-(2-(4-bromobenzylidene)hydrazinyl)thiazole and 4-adamantyl-(2-(2-hydroxybenzylidene)hydrazinyl)thiazole exhibited comparable antiglycation potential. The antioxidant potential of compound 4-adamantyl-(2-(3-nitrobenzylidene)hydrazinyl)thiazole was found to be excellent. A further test was used to check toxicity and all compounds were found to be biocompatible. We also investigated, through docking studies, the way in which these compounds interact with the human proteins albumin and pancreatic α-amylase.


Asunto(s)
Antioxidantes , Tiazoles , Humanos , Antioxidantes/farmacología , Simulación del Acoplamiento Molecular , Tiazoles/farmacología , Tiazoles/química , Hipoglucemiantes/farmacología , alfa-Amilasas , Relación Estructura-Actividad
16.
Food Res Int ; 157: 111205, 2022 07.
Artículo en Inglés | MEDLINE | ID: mdl-35761527

RESUMEN

Narrow leaf plantain, white clover, perennial ryegrass, and tall fescue are non-conventional edible plants having widespread existence in many temperate and Mediterranean regions worldwide. These edible plants represent valuable food resources, and genetic and genomic approaches to improving and utilising these plants for human consumption are ongoing. These plants have characteristic high antioxidant capacities attributed to their polyphenol composition. This study performed the screening of polyphenols by applying a high-throughput LC-ESI-QTOF/MS technique and determined their antioxidant potential. Seventy different polyphenols were detected with 25 compounds in narrow leaf plantain, 27 in white clover, 15 in perennial ryegrass and 14 in tall fescue. Total phenolic content (TPC) was highest in white clover (1.81 ± 0.16 mg GAE/g fresh weight (FW)), while total tannin content (TTC) was highest in perennial ryegrass (0.89 ± 0.04 mg GAE/g FW) compared with their three counterparts, respectively. Narrow leaf plantain and white clover had greater total flavonoid content (TFC) than perennial ryegrass and tall fescue. The results of this investigation provided valuable information about the unique phenolic composition and antioxidant potential of the studied non-conventional edible plants that could be used to promote their utilization in human foods, nutraceutical preparations and functional foods besides being used as a valuable source of polyphenols for different industrial sectors. Besides, the results of the study can also be used as a baseline information for the planned and targeted delivery of bioactive compounds like polyphenols to the animals by devising an appropriate feeding strategy based on the phenolic composition of these plants.


Asunto(s)
Plantago , Polifenoles , Animales , Antioxidantes/análisis , Fenoles/análisis , Hojas de la Planta/química , Plantas Comestibles , Polifenoles/análisis
17.
Materials (Basel) ; 15(16)2022 Aug 17.
Artículo en Inglés | MEDLINE | ID: mdl-36013795

RESUMEN

The disposal of steel slag leads to the occupation of large land areas, along with many environmental consequences, due to the release of poisonous substances into the water and soil. The use of steel slag in concrete as a sand-replacement material can assist in reducing its impacts on the environment and can be an alternative source of fine aggregates. This is the very first paper that seeks to experimentally investigate the cumulative effect of steel slag and polypropylene fibers, particularly on the impact resistance of concrete. Various concrete mixes were devised by substituting natural sand with steel slag at volumetric replacement ratios of 0%, 10%, 20%, 30%, and 40%, with and without fibers. Polypropylene fibers of 12 mm length were introduced into the steel slag concrete at 0%, 0.5%, and 1.0% by weight of cement as a reinforcing material. Performance evaluation of each mix through extensive experimental testing indicated that the use of steel slag as partial substitution of natural sand, up to a certain optimum replacement level of 30%, considerably improved the compressive strength, flexural strength, and tensile strength of the concrete by 20.4%, 23.8%, and 17.0%, respectively. Furthermore, the addition of polypropylene fibers to the steel slag concrete played a beneficial role in the improvement of strength characteristics, particularly the flexural strength and final drop weight impact energy, which had a maximum rise of 48.1% and 164%, correspondingly. Moreover, integral structure and analytical analyses have also been performed in this study to validate the experimental findings. The results obtained encourage the use of fiber-reinforced steel slag concrete (FRSLC) as a potential impact-resistant material considering the environmental advantages, with the suggested substitution, of an addition ratio of 30% and 1.0% for steel slag and polypropylene fibers, respectively.

18.
J Pak Med Assoc ; 61(10): 1025-7, 2011 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-22356044

RESUMEN

Yolk sac tumour is germ cell tumour commonly found in children and infants under three years of age in its pure form with a good prognosis. The commonest location for the yolk sac tumour is gonads i.e. testis and gonads. Yolk sac tumour is rarely reported in extra- gonadal locations. Parapharyngeal space is an uncommon site for mature teratoma and very few cases have been reported in adults and children. Malignant transformation in a mature teratoma in the extragonadal sites has been reported but development of yolk sac tumour has not been reported so far in the world literature. We report to our knowledge, the only and first case of yolk sac tumour arising in a mature teratoma presenting as a parapharyngeal mass in a four year old male child.


Asunto(s)
Tumor del Seno Endodérmico/patología , Neoplasias Faríngeas/patología , Teratoma/patología , Preescolar , Humanos , Masculino
19.
J Imaging ; 7(7)2021 Jul 15.
Artículo en Inglés | MEDLINE | ID: mdl-39080905

RESUMEN

The JPEG format, consisting of a set of image compression techniques, is one of the most commonly used image coding standards for both lossy and lossless image encoding. In this format, various techniques are used to improve image transmission and storage. In the final step of lossy image coding, JPEG uses either arithmetic or Huffman entropy coding modes to further compress data processed by lossy compression. Both modes encode all the 8 × 8 DCT blocks without filtering empty ones. An end-of-block marker is coded for empty blocks, and these empty blocks cause an unnecessary increase in file size when they are stored with the rest of the data. In this paper, we propose a modified version of the JPEG entropy coding. In the proposed version, instead of storing an end-of-block code for empty blocks with the rest of the data, we store their location in a separate buffer and then compress the buffer with an efficient lossless method to achieve a higher compression ratio. The size of the additional buffer, which keeps the information of location for the empty and non-empty blocks, was considered during the calculation of bits per pixel for the test images. In image compression, peak signal-to-noise ratio versus bits per pixel has been a major measure for evaluating the coding performance. Experimental results indicate that the proposed modified algorithm achieves lower bits per pixel while retaining quality.

20.
Front Plant Sci ; 12: 644904, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33868344

RESUMEN

The breeding for varieties tolerant of adverse growing conditions is critical for sustainable agriculture, especially for ramie (Boehmeria nivea L.). However, a lack of information on the tolerance of ramie to nutrient-deficient conditions has hindered efforts to breed ramie varieties tolerant of such conditions. The main objective of this study was to explore the tolerance strategies of ramie plants under poor soil conditions using long-term (8-9 years) field trials. Genotypes of Duobeiti 1 and Xiangzhu XB were highly tolerant of poor soil conditions. The contributions of seasonal nutrient cycling and rhizobacteria to the ability of ramie to tolerate poor soil were tested. Nitrogen and phosphorus retranslocation to the root at the end of the growing season helped ramie adapt to poor soil conditions. The contribution of the microbial community was analyzed using high-throughput Illumina MiSeq sequencing technology. The enrichment of beneficial bacteria (mainly Bradyrhizobium, Gaiella, and norank_o_Gaiellales) and the reduction of harmful fungi (mainly Cladosporium and Aspergillus) also contributed to the ability of ramie to tolerate poor soils. The results of this study provide new insight into the ability of ramie to tolerate adverse conditions and aid future efforts to breed and cultivate ramie tolerant of adverse conditions.

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