RESUMEN
A rotavirus G1P[8] strain C1-81 was isolated from a 5-month-old female infant admitted to hospital with fever and severe diarrhea in Incheon, South Korea. To investigate its full genomic relatedness and its group, the full genome of strain C1-81 was determined. Based on a full genome classification system, C1-81 was shown to possess the typical Wa-like genotype constellation: G1-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1. On the basis of sequence similarities, the strain was shown to be the closest related strain to contemporary human rotavirus strains with recent strains isolated in Asia. This C1-81 strain showed the highest degree of nucleic acid similarity (98.8% and 97%) to G1 B4633-03 and P[8] (Thai-1604 and Dhaka8-02), respectively. This is the first report that group A rotavirus was analyzed with G1P[8] in South Korea. The study of the complete genome of the virus will help understanding of the evolution of rotavirus.
Asunto(s)
Genoma Viral , ARN Viral/genética , Rotavirus/genética , Análisis de Secuencia de ADN , Diarrea/virología , Femenino , Genotipo , Humanos , Lactante , Datos de Secuencia Molecular , Filogenia , República de Corea , Rotavirus/aislamiento & purificación , Infecciones por Rotavirus/virología , Homología de Secuencia de Ácido NucleicoRESUMEN
Fractional photothermolysis has become popular in the recent years and is currently widely used for the treatment of scars and for photo-rejuvenation purposes. The fractional photothermolysis is to thermally alter a 'fraction' of the skin, leaving intervening areas of normal skin untouched, which rapidly repopulate the altered columns of tissue. Fractional photothermolysis is subdivided into non-ablative and ablative fractional resurfacing. Ablative fractional resurfacing uses fractional CO(2) or Er:YAG lasers to create deeper columns of thermal damage.Few studies have compared fractional CO(2) and Er:YAG lasers on scars and cutaneous photodamages by a split trial. In this pilot study, we have compared the effects, down time, postprocedure erythema, pain of CO(2) and Er:YAG fractional lasers using analysis of clinical photographs, dermoscopic findings and patient's rate of satisfaction.