Detalles de la búsqueda
1.
In vivo evaluation of the uptake of [(123)I]FIAU, [(123)I]IVFRU and [(123)I]IVFAU by normal mouse brain: potential for noninvasive assessment of HSV-1 thymidine kinase gene expression in gliomas.
Nucleosides Nucleotides Nucleic Acids
; 27(1): 57-66, 2008 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18188770
2.
The cytostatic activity of 5-(1-azidovinyl)-2'-deoxyuridine (AzVDU) against herpes simplex virus thymidine kinase gene-transfected FM3A cells is due to inhibition of thymidylate synthase and enhanced by UV light (lambda = 254 nm) exposure.
FEBS Lett
; 373(1): 41-4, 1995 Oct 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-7589430
3.
Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT).
Curr Med Chem
; 7(10): 995-1039, 2000 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-10911016
4.
Enzyme-targeted, nucleoside-based radiopharmaceuticals for scintigraphic monitoring of gene transfer and expression.
Curr Pharm Des
; 7(18): 1893-906, 2001 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-11772356
5.
Synthesis of N-(3,6-dihydro-1(2H)-pyridinyl)benzamides with hyperglycemic-hypoglycemic activity.
J Med Chem
; 30(1): 104-8, 1987 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-3806586
6.
Synthesis, biological evaluation, calcium channel antagonist activity, and anticonvulsant activity of felodipine coupled to a dihydropyridine-pyridinium salt redox chemical delivery system.
J Med Chem
; 39(23): 4576-82, 1996 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-8917646
7.
Some reactions of 1,4-dihydropyridines with organic azides. Synthesis of 2,7-diazabicyclo[4.1.0]hept-3-enes with analgesic and antiprotozoal activity.
J Med Chem
; 24(4): 462-4, 1981 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-7265132
8.
Synthesis and antiviral activity of novel 5-(1-azido-2-haloethyl) and 5-(1-azido-, amino-, or methoxyethyl) analogs of 2'-deoxyuridine.
J Med Chem
; 36(17): 2470-4, 1993 Aug 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-8394933
9.
Syntheses of N-substituted 2(3,4)-pyridylcarboxylic acid hydrazides with analgesic and antiinflammatory activity.
J Med Chem
; 22(9): 1079-82, 1979 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-314983
10.
Synthesis, in vitro biological stability, and anti-HIV activity of 5-halo-6-alkoxy(or azido)-5,6-dihydro-3'-azido-3'-deoxythymidine diastereomers as potential prodrugs to 3'-azido-3'-deoxythymidine (AZT).
J Med Chem
; 37(25): 4297-306, 1994 Dec 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-7996541
11.
Synthesis and tumor uptake of 5-halo-1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)[2-14C]uracils.
J Med Chem
; 30(4): 670-5, 1987 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-2951522
12.
Synthesis and antiviral (HIV-1, HBV) activities of 5-halo-6-methoxy(or azido)-5,6-dihydro-3'-fluoro-3'-deoxythymidine diastereomers. Potential prodrugs to 3'-fluoro-3'-deoxythymidine.
J Med Chem
; 37(21): 3554-60, 1994 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-7932583
13.
Synthesis of N-[[(substituted-phenyl)carbonyl]amino]-1,2,3,6-tetrahydropyridines with analgesic and hyperglycemic activity.
J Med Chem
; 25(6): 720-3, 1982 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-7097725
14.
Synthesis of N-(carbonylamino)-1,2,3,6-tetrahydropyridines with analgesic, antiinflammatory, and hyperglycemic activity.
J Med Chem
; 25(2): 191-5, 1982 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-7057427
15.
Design and synthesis of 4,5-diphenyl-4-isoxazolines: novel inhibitors of cyclooxygenase-2 with analgesic and antiinflammatory activity.
J Med Chem
; 44(18): 2921-7, 2001 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-11520200
16.
Design and synthesis of celecoxib and rofecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of sulfonamide and methylsulfonyl pharmacophores by an azido bioisostere.
J Med Chem
; 44(18): 3039-42, 2001 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-11520213
17.
Synthesis and tumor uptake of 5-82Br- and 5-131I-labeled 5-halo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracils.
J Med Chem
; 32(6): 1289-94, 1989 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-2524593
18.
Synthesis and cellular uptake of 2'-substituted analogues of (E)-5-(2-[125I]iodovinyl)-2'-deoxyuridine in tumor cells transduced with the herpes simplex type-1 thymidine kinase gene. Evaluation as probes for monitoring gene therapy.
J Med Chem
; 40(14): 2184-90, 1997 Jul 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-9216837
19.
Synthesis and calcium channel antagonist activity of dialkyl 4- (dihydropyridinyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylates.
J Med Chem
; 30(4): 640-6, 1987 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-3560157
20.
Synthesis and calcium channel antagonist activity of dialkyl 1,4-dihydro-2,6-dimethyl-4-(pyridinyl)-3,5-pyridinedicarboxylates.
J Med Chem
; 29(12): 2524-9, 1986 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-3783612