3D printing in endodontics: report of three clinical cases with innovative approaches.

3D printing is a process whereby a given material is deposited in successive layers to create a 3D object. In dentistry, this technology involves three steps: digital data acquisition using a scanner and/or CBCT, data processing and design within a software application, and manufacturing through 3D printing. The aim of the present article is to discuss the clinical application of 3D printing in endodontics through the presentation of three specific and original endodontic clinical cases. Innovative approaches were utilized in these cases for the treatment of a calcified root canal, periapical surgery, and autotransplantation. The results of all three cases were promising regarding proper case selection and in the design process. 3D-printing technology may be helpful to reduce surgical time, operator bias, and the risk of procedural errors.

Access Cavity Preparation and Localization of Root Canals Using Guides in 3D-Printed Teeth with Calcified Root Canals: An In Vitro CBCT Study.

Pulp canal obliteration (PCO) is a significant complication in endodontics that can occur due to various factors. Cone beam computed tomography (CBCT) is a useful diagnostic tool for identifying root canal anatomy and variations, and guided endodontics is emerging as an alternative treatment solution for teeth with partially or entirely obliterated pulpal canals. However, the accuracy of CBCT-guided 3D-printed guides on different materials and layer thicknesses is not well understood. Therefore, this study aimed to evaluate the accuracy of guides prepared using CBCT images on 3D-printed teeth with stereolithography (SLA) using three different materials and two different layer thicknesses. This study found that 3D-printed guides were accurate and reliable for accessing 3D-manufactured obliterated teeth and reaching the apical area. No significant differences in distance or angle measurements were found when different guide materials were used, suggesting that materials can be selected based on availability and cost. These findings contribute to the knowledge base regarding the effectiveness of 3D printing technology in guided endodontics and can help to identify the most suitable materials and techniques for this application.

Sealing ability of three different materials to repair furcation perforations using computerized fluid filtration method.

Background. The present study aimed to evaluate the sealing ability of three different calcium silicate-based materials in furcation perforations. Methods. Seventy-six human mandibular molar teeth were selected. Perforations were created in the center of the pulp chamber floor. The experimental teeth were randomly divided into three groups (n=22). Perforations were repaired with MTA Angelus, Endocem MTA, or EndoSequence BioCeramic Root Repair Material Fast Set Putty (BC-RRM Putty). Microleakage of the different repair materials to be tested was measured by computerized fluid filtration method at 24- and 72-hour intervals. Results. For each time interval, no statistically significant difference was observed between the groups. For Endocem MTA and BC-RRM Putty groups, the difference between the leakage values measured at both periods was not statistically significant (P > 0.05). However, there was a significant difference for the MTA Angelus group (P < 0.05). Conclusion. All the calcium silicate-based materials used in the present study showed similar performance in repairing furcation perforations at 24- and 72-hour intervals.

Effect of cone beam computed tomography voxel size and dental specialty status on the agreement of observers in the detection and measurement of periapical lesions.

OBJECTIVE: To compare observer agreement between endodontists and oral and maxillofacial radiologists (OMRs) in the detection and measurement of periapical lesions as depicted in cone beam computed tomography (CBCT) with 2 voxel sizes. STUDY DESIGN: In total, 256 CBCT images of maxillary molars were evaluated by 2 endodontists and 2 OMRs. Images were obtained at voxel sizes of 0.2 and 0.4 mm. Observers evaluated 64 endodontically and 64 nonendodontically treated teeth for the presence of periapical lesions using a 5-point confidence scale. Weighted κ values were calculated to determine intra- and interobserver agreement. Intraclass correlation coefficients (ICCs) were calculated to assess intra- and interobserver agreement in width and height measurements of the lesions. RESULTS: Intraobserver agreement ranged from fair to almost perfect, with κ values higher for the OMRs than for the endodontists. Interobserver agreement between endodontists ranged from fair to moderate at the 0.2mm voxel size and was slight at 0.4 mm. Agreement between OMRs was almost perfect at 0.2 mm and ranged from substantial to almost perfect at 0.4 mm. ICC was excellent for all observers in all conditions. CONCLUSIONS: Intra- and interobserver reliability was affected by voxel size and specialty. Correlation for measurements exhibited no variation.

Versatility of high resolution ultrasonography in the assessment of granulomas and radicular cysts: a comparative in vivo study.

OBJECTIVES: To evaluate and compare the diagnostic potential of high resolution ultrasound with periapical radiographs (PR) and CBCT in assessing granulomas and radicular cysts. METHODS: This study included a total of 33 teeth from 33 patients with periapical lesions. Subjects were distributed among three groups. A consisted of teeth that were extracted. B consisted of teeth treated with root-canal treatment followed by apical surgery. C consisted of teeth treated with root-canal treatment only. Pre-treatment PR, ultrasound and CBCT images were obtained for Groups A, B and C and 6 month post-treatment PR and ultrasound images were obtained for Groups B and C. In addition, histopathological analysis was performed on lesions in Groups A and B. Lesions were classified as either cystic lesions or granulomas. Width, height, depth, surface area and volume of lesions were measured using the built-in softwares of the appropriate imaging modalities. Measurements were compared by Wilcoxon and paired sample t tests. Ultrasound and histopathological findings were compared with κ and Mc Nemar. Statistical significance was set at p < 0.05. RESULTS: κ coefficient (0.667; p = 0.002) suggested good agreement between ultrasound and histopathology. No statistically significant differences were found among periapical radiography, CBCT and ultrasound in the pre-treatment measurements of lesion width ( p = 0.308) or between CBCT and periapical radiography in the pre-treatment measurements of lesion height ( p = 0.863). In all cases, mean measurement values for all variables were lower for ultrasound than for CBCT. CONCLUSION: Ultrasound provided useful information for the diagnosis and assessment of granulomas and radicular cysts.

Accuracy of linear and volumetric measurements of artificial ERR cavities by using CBCT images obtained at 4 different voxel sizes and measured by using 4 different software: an ex vivo research.

OBJECTIVES: To compare the accuracy of linear and volumetric measurements of artificial external root resorption (ERR) cavities by cone beam CT (CBCT) images obtained at four voxel sizes and by using four different software ex vivo. METHODS: ERR cavities were created on 40 extracted single rooted anterior teeth. Images were obtained by using Planmeca CBCT unit at endo mode (0.075 mm); high-resolution mode (0.1 mm); high-definition mode (0.15 mm) and normal resolution mode (0.2 mm) voxel sizes. Images were analyzed by two observers using four different software (Romexis, 3D Doctor, ITK-SNAP, and OsiriX). (1) Diameter; (2) height; (3) depth; and (4) volume of the ERR were measured. CBCT measurements were then compared with direct physical measurements. ANOVA was used with general linear model analysis. The significance level was set at p < 0.05. RESULTS: One-way ANOVA general linear model analysis showed no significant difference between or within observers for diameter, height, depth and volume measurements (p > 0.05). We found significant differences for diameter and volume measurements among softwares in terms of mean differences as compared to mean standard direct measurements (p < 0.05). We found statistically significant differences among voxel sizes and software for height measurements (p < 0.05). In addition, we found significant differences for diameter and volume measurements (p < 0.05) suggesting more accurate measurements for the cervical region when compared to apical region. CONCLUSIONS: Observers using CBCT images obtained at four voxel sizes performed similarly in the quantification of artificial ERR with clinically insignificant distinction between CBCT softwares used.

Comparison of the accuracy of periapical radiography with CBCT taken at 3 different voxel sizes in detecting simulated endodontic complications: an ex vivo study.

OBJECTIVES: To compare the accuracy of a photostimulable phosphor plateP sensor with cone beam CT (CBCT) images in the detection of simulated endodontic complications. METHODS: Following simulated endodontic complications were created in 40 extracted human mandibular molar teeth: Group 1, Instrument separation (N = 10); Group 2, Strip perforation (N = 10); Group 3, Underfilling of root canals (N = 10); Group 4, Overfilling of root canals (N = 10). Intraoral and CBCT images (voxel size: 0.075 , 0.1 and 0.2 mm) were taken. Images were scored by 4 observers according to a 5-point scale. Weighted kappa and intraclass correlation coefficients were calculated. Receiveroperating characteristic analysis was performed and DeLong test was used to compare areaunder curve values. Significance level was set at p < 0.05. RESULTS: Intraobserver kappa ranged from moderate (0.417) to excellent (0.918). Intraclass correlation coefficients ranged from moderate (0.482) to excellent (0.855). For Group 1 (instrument separation) the highest Az values were obtained for intraoral images and the lowest for CBCT (0.2 mm voxel size) (p < 0.05). The highest Az values were obtained for Group 2 (strip perforation) among all groups. With all CBCT image settings, observers performed similarly and better than intraoral images (p < 0.05) in detection of strip perforation. For Group 3 (underfilling), higher Az values for CBCT images were obtained compared to intraoral images without statistically significant difference (p > 0.05). For Group 4 (overfilling), higher Az values for CBCT images were obtained when compared to digital intraoral for observer 1 and 2 (p < 0.05). CONCLUSIONS: CBCT images may be useful as an adjunct to periapical imaging in the detection of endodontic complications, such as strip perforation and overfilled root canals.

Evaluation of 3 Different Retreatment Techniques in Maxillary Molar Teeth by Using Micro-computed Tomography.

INTRODUCTION: Nonsurgical retreatment procedure involves the complete removal of the previous filling material to allow thorough instrumentation, disinfection, and refilling of root canal system. We aimed to determine the residuals of the root-filling material by using 3 different retreatment techniques with the aid of micro-computed tomography. METHODS: Thirty extracted human maxillary molar teeth were included. All root canals were also obturated with F2 ProTaper single cones and AH Plus sealer. The following retreatment techniques were performed: group 1, ProTaper retreatment files; group 2, Mtwo retreatment files; and group 3, ProFile files. For the assessment of residual filling material, preoperative and postoperative micro-computed tomography scans were compared with each other, and the working time was recorded. One-way analysis of variance was used to analyze the differences between the groups. The significance level was set at P < .05. RESULTS: None of the retreatment techniques were capable of removing the whole filling material. The percentages of the residual filling materials for groups 1, 2, and 3 were 34.45, 45.43, and 23.63, respectively. There was a statistically significant difference between groups 2 and 3 (P < .05). ProTaper and ProFile instruments required less time for the removal of filling materials when compared with Mtwo instrument. CONCLUSIONS: ProFile files revealed the best results for endodontic retreatment in terms of both removing capacity and time requirement.