Detalles de la búsqueda
1.
An Adverse Outcome Pathway Network for Chemically Induced Oxidative Stress Leading to (Non)genotoxic Carcinogenesis.
Chem Res Toxicol
; 36(6): 805-817, 2023 06 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-37156502
2.
Application of AOPs to assist regulatory assessment of chemical risks - Case studies, needs and recommendations.
Environ Res
; 217: 114650, 2023 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36309218
3.
Consideration of pathways for immunotoxicity of per- and polyfluoroalkyl substances (PFAS).
Environ Health
; 22(1): 19, 2023 02 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36814257
4.
Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells.
Arch Toxicol
; 97(4): 1113-1131, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36864359
5.
Towards achieving a modern science-based paradigm for agrochemical carcinogenicity assessment.
Regul Toxicol Pharmacol
; 137: 105301, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36436696
6.
Epigenome-wide association study of incident type 2 diabetes: a meta-analysis of five prospective European cohorts.
Diabetologia
; 65(5): 763-776, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35169870
7.
Analyses of Transcriptomics Cell Signalling for Pre-Screening Applications in the Integrated Approach for Testing and Assessment of Non-Genotoxic Carcinogens.
Int J Mol Sci
; 23(21)2022 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36361516
8.
Relevance of In Vitro Transcriptomics for In Vivo Mode of Action Assessment.
Chem Res Toxicol
; 34(2): 452-459, 2021 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33378166
9.
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Crit Rev Toxicol
; 51(2): 141-164, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33853480
10.
Biomarkers of effect as determined in human biomonitoring studies on hexavalent chromium and cadmium in the period 2008-2020.
Environ Res
; 197: 110998, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33713715
11.
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology.
Regul Toxicol Pharmacol
; 125: 105020, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-34333066
12.
A Case Study with Triazole Fungicides to Explore Practical Application of Next-Generation Hazard Assessment Methods for Human Health.
Chem Res Toxicol
; 33(3): 834-848, 2020 03 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32041405
13.
Towards a mechanism-based approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals.
Crit Rev Toxicol
; 50(9): 725-739, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-33236972
14.
Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts.
Arch Toxicol
; 94(12): 4173-4196, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32886187
15.
Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens.
Arch Toxicol
; 94(8): 2899-2923, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32594184
16.
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Regul Toxicol Pharmacol
; 118: 104789, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33035627
17.
DNA methylation markers associated with type 2 diabetes, fasting glucose and HbA1c levels: a systematic review and replication in a case-control sample of the Lifelines study.
Diabetologia
; 61(2): 354-368, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29164275
18.
Is current risk assessment of non-genotoxic carcinogens protective?
Crit Rev Toxicol
; 48(6): 500-511, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29745287
19.
Letter to the editor regarding the review article by Yamada et al. (2021) titled "Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR)".
Crit Rev Toxicol
; 52(5): 397-398, 2022 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36102316
20.
Origin of the TTC values for compounds that are genotoxic and/or carcinogenic and an approach for their re-evaluation.
Crit Rev Toxicol
; 47(8): 705-727, 2017 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-28510487