Daily Undulating Periodization Is More Effective Than Nonperiodized Training on Maximal Strength, Aerobic Capacity, and TCD4+ Cell Count in People Living With HIV.

ABSTRACT: Soares, VL, Soares, WF, Zanetti, HR, Neves, FF, Silva-Vergara, ML, and Mendes, EL. Daily undulating periodization is more effective than nonperiodized training on maximal strength, aerobic capacity, and TCD4+ cell count in people living with HIV. J Strength Cond Res 36(6): 1738-1748, 2022-The aim of this study was to evaluate the effects of daily undulating periodization (DUP) and nonperiodized training (NPT) programs on maximal muscle strength, body composition, aerobic capacity, muscle power, and immune markers in people living with HIV (PLWHIV). A total of 41 PLWHIV were randomly assigned to control (CON [n = 15]), DUP (n = 13), and NPT (n = 13) groups. The DUP and NPT groups performed combined training 3 times a week on nonconsecutive days during 12 weeks, whereas the CON group was asked to maintain their current level of activity. After the 12-week training program, DUP produced greater gains in muscle strength (except for bench press), V̇o2peak, and muscle power than NPT (p < 0.05). Compared to CON, the training groups showed significantly (p < 0.05) increased muscle strength (DUP = 31.0 ± 13.9 kg; NPT = 17.7 ± 9.2 kg; CON = -0.3 ± 1.5 kg), fat-free mass (DUP = 1.9 ± 1.5 kg; NPT = 1.4 ± 1.9 kg; CON = -0.1 ± 1.2 kg), and metabolic equivalent (DUP = 2.3 ± 1.3; NPT = 1.8 ± 1.9), and decreased body fat mass (DUP = -2.1 ± 1.6 kg; NPT = -1.4 ± 1.5 kg; CON = 0.1 ± 0.2) and functional aerobic impairment (DUP = -35.9 ± 17.0%; NPT = -25.8 ± 22.0%; CON = 0.8 ± 3.0%). There was an increase in TCD4+ cells only in the DUP group (p < 0.05). The training effect generally provided a positive correlation between change in leg press strength (r = 0.393, p < 0.05), triceps pulley strength (r = 0.417, p < 0.05), lat pull-down strength (r = 0.459, p < 0.05), and muscle power (r = 0.324, p < 0.05) with changing CD4 + lymphocyte count. Daily undulating periodization protocol showed to be safe, applicable, and more efficient for increasing strength, aerobic capacity, and TCD4+ cells compared to NPT in PLWHIV.

Triad of the Ischemic Cardiovascular Disease in People Living with HIV? Association Between Risk Factors, HIV Infection, and Use of Antiretroviral Therapy.

PURPOSE OF REVIEW: This review is focused on cardiovascular risk factors in HIV-infected people. RECENT FINDINGS: Antiretroviral therapy (ART) has significantly increased the life expectancy of HIV-infected people. Thus, this population has experienced non-HIV-related diseases, mainly cardiovascular diseases. Thus, in our review, we intend to understand the cardiovascular risk factors that trigger this situation. We have demonstrated that both ART and traditional cardiovascular risk factors contribute to the development of cardiovascular disease in HIV-infected people. Thus, it becomes important to stratify the risk factors to reduce this scenario.

Waist circumference to height ratio predicts inflammatory risk in children.

BACKGROUND: The increase in obesity, especially the increase of visceral fat, has been directly associated with health risk. Additionally, a waist-to-height ratio (WHtR) (0.5) has been proposed as an indicator of early health risk. AIMS: To test the association between anthropometric measurements and inflammatory mRNA expression and to evaluate the effectiveness of WHtR to predict inflammatory risk in children. SUBJECTS AND METHODS: Anthropometric measurements and fasting blood samples were collected in 94 Brazilian children (46 boys) aged 9-11 years. Children were identified as being at inflammatory risk based on cytokine mRNA expression levels at and above the 75th percentile. Inflammatory cytokine mRNA expression levels were determined through buff-coat using real-time polymerase chain reaction. RESULTS: Body mass index (BMI), waist circumference (WC) and WHtR showed moderate-to-strong association with inflammatory cytokine mRNA gene expression. WHtR = 0.51 was the most accurate cut-off point in distinguishing children at inflammatory risk. Compared with children with WHtR <0.51, children with a WHtR ≥0.51 presented an odds ratio of 2.643 (95% CI = 1.749-3.994) for both diagnosed IL-6 and MCP-1 above the 75th percentile and 2.796 (95% CI = 1.802-4.338) for TNF-α above the 75th percentile. WHtR = 0.50 presented the same values of sensitivity and odds ratio and ∼7% lower specificity compared to WHtR = 0.51. CONCLUSION: Anthropometric measurements have shown a moderate-to-strong association with the mRNA expression of inflammatory genes and a WHtR of 0.5 could serve as a cut-off point, suggesting increased risk of inflammatory responses.

Anthropometry and physical activity level in the prediction of metabolic syndrome in children.

OBJECTIVE: To evaluate the effectiveness of anthropometric measures and physical activity level in the prediction of metabolic syndrome (MetS) in children. DESIGN: Cross-sectional study with children from public and private schools. Children underwent an anthropometric assessment, blood pressure measurement and biochemical evaluation of serum for determination of TAG, HDL-cholesterol and glucose. Physical activity level was calculated and number of steps per day obtained using a pedometer for seven consecutive days. SETTING: Viçosa, south-eastern Brazil. SUBJECTS: Boys and girls (n 187), mean age 9·90 (SD 0·7) years. RESULTS: Conicity index, sum of four skinfolds, physical activity level and number of steps per day were accurate in predicting MetS in boys. Anthropometric indicators were accurate in predicting MetS for girls, specifically BMI, waist circumference measured at the narrowest point and at the level of the umbilicus, four skinfold thickness measures evaluated separately, the sum of subscapular and triceps skinfold thickness, the sum of four skinfolds and body fat percentage. CONCLUSIONS: The sum of four skinfolds was the most accurate method in predicting MetS in both genders.

[Association between excessive TV viewing time and body mass index among Brazilian adolescents: quantile regression analysis of the National Student Health Survey (PeNSE), 2015]. / Associação entre tempo excessivo frente à TV e índice de massa corporal em adolescentes brasileiros: uma análise de regressão quantílica da PeNSE, 2015.

The study aimed to investigate whether excessive TV viewing time is associated with body mass index (BMI), irrespective of physical activity (PA) and interaction with consumption of ultra-processed foods (UPFs), among Brazilian adolescents. It is a cross-sectional study with data on 13-17-year-old adolescents from the 2015 National Student Health Survey. BMI was the outcome (direct measurement of height and body mass) and exposure was excessive TV viewing time (>2 h/day), daily consumption of UPFs and PA. Quantile regression was used to test associations and interactions. Excessive screen time was associated with higher BMI values (e.g., 25th percentile =0.060 kg/m² versus 95th percentile =0.891 kg/m², p<0.001). After adjusting for PA, the association remained, however, attenuated. The inclusion of UPFs in the model potentiated the association (e.g., 25th percentile =0.062 kg/m² versus 95th percentile =0.956 kg/m², p<0.001). Excessive screen time was associated with BMI percentiles, irrespective of PA - the absence of PA and the presence of UPF consumption affect the upper BMI percentiles more. Actions to reduce excessive TV viewing time, consumption of UPFs and promoting PA are essential to positively impact BMI and its reflexes on the health of Brazilian adolescents.

O objetivo do estudo foi investigar se tempo excessivo frente à TV está associado com índice de massa corporal (IMC), independente da atividade física (AF) e da interação com consumo de alimentos ultraprocessados (AUPs), em adolescentes brasileiros. Estudo transversal com dados de adolescentes de 13-17 anos da Pesquisa Nacional de Saúde do Escolar 2015. IMC foi o desfecho (medida direta da estatura e massa corporal) e as exposições foram tempo excessivo frente à TV (>2 h/dia), consumo diário de AUPs e AF. Regressão quantílica foi usada para testar associações e interações. Tempo excessivo frente à TV foi associado a maiores valores de IMC (ex.: 25º percentil =0,060 kg/m² versus 95º percentil =0,891 kg/m², p<0,001). Após ajuste para AF, a associação se manteve, porém, atenuada. A inclusão de AUPs no modelo potencializou a associação (ex.: 25º percentil =0,062 kg/m² versus 95º percentil =0,956 kg/m², p<0,001). Tempo excessivo frente à TV foi associado a percentis do IMC, independente da AF - ausência da AF e presença do consumo de AUPs afetam mais os percentis superiores do IMC. Ações para reduzir tempo excessivo frente à TV, consumo de AUPs e fomentar AF, são essenciais para impactar positivamente no IMC e seus reflexos na saúde dos adolescentes brasileiros.

Time Course of Recovery for Performance Attributes and Circulating Markers of Muscle Damage Following a Rugby Union Match in Amateur Athletes.

BACKGROUND: We sought to determine the time course of changes in neuromuscular performance and muscle damage following a single rugby union match. METHODS: Fourteen male amateur rugby players (28.9 ± 3.5 yrs; 1.7 ± 5.1 m; 86.1 ± 11.1 kg) participated. Plasma activity of creatine kinase ([CK]) and lactate dehydrogenase (LDH), L-run test (change of direction) and 30-m sprint (T30; speed) with 10-m lap time (T10; acceleration) were assessed on six occasions: one week before the match (PRE) and immediately, 24, 48, 72, and 96 h post-match. RESULTS: Relative to PRE, LDH was elevated immediately post-match (+33.6% ± 13.6%; p < 0.001) and [CK] was elevated immediately (+64.1% ± 38.8%, p = 0.001) and 24 h post-match (+352% ± 317%; p = 0.024). L-run test time increased 16.0 ± 8.7% relative to PRE at 24 h post (p < 0.001) and remained elevated through 96 h post-match (p < 0.05). T10 and T30 times increased relative to PRE immediately post-match (+12.0% ± 10.4%, p = 0.008; and +6.1% ± 4.9%; p = 0.006, respectively), though T30 times were similar to baseline by 48 h post-match whereas T10 times remained elevated through 72 h post-match. CONCLUSIONS: A single, competitive rugby union match induces significant muscle damage and performance decrements with distinct time courses of recovery in amateur athletes. Notably, change of direction attributes (i.e., L-run) appear to have the longest time course to full recovery.

Effects of Exercise Training and Statin Use in People Living with Human Immunodeficiency Virus with Dyslipidemia.

PURPOSE: To evaluate the effects of the combination of exercise training (ET) and statins in people living with human immunodeficiency virus. METHODS: This was a randomized, double-blind, placebo-controlled clinical trial. Eighty-three people living with human immunodeficiency virus were assigned to either placebo (PL), statins (STA), PL + ET (PLET) or STA + ET (STAET) groups. Volunteers assigned to STA and STAET groups were administered 10 mg of rosuvastatin, whereas the PL and PLET groups were administered a placebo. The PLET and STAET groups performed ET three times a week. Before and after the 12-wk follow-up, the volunteers underwent to anthropometric assessment and blood collection to evaluate lipid profile, cardiovascular markers, inflammatory profile; a Doppler ultrasound examination, muscle strength (MS) and cardiorespiratory fitness (CF) tests were performed. RESULTS: There was a decrease in total cholesterol, triglycerides, low-density lipoprotein, C-reactive protein, fibrinogen, interleukin (IL)-1ß and right carotid intima-media thickness in the STA, PLET, and STAET groups compared with PL group (P < 0.001). Furthermore, there was a decrease in total cholesterol, triglycerides, low-density lipoprotein, IL-1ß, IL-6, and IL-8 levels and in left and right carotid intima-media thickness and an increase in HDL-c levels in the STAET groups compared with the STA (P ≤ 0.001) and PLET groups (P ≤ 0.001). There was an increase in IL-10 levels, peak-systolic velocity, end-diastolic velocity, wall shear rate in the PLET and STAET groups compared with the PL (P ≤ 0.001) and STA groups (P ≤ 0.001). The PLET and STAET groups reduced body fat mass, body fat percentage and increased lean body mass, MS and CF compared with PL (P ≤ 0.001) and STA (P ≤ 0.001) groups. CONCLUSIONS: The combination of ET and statins is useful to enhance lipid and inflammatory profiles, reduce cardiovascular disease markers, and improve Doppler ultrasound findings, MS and CF in people living with HIV.

Utility of anthropometric indicators to screen for clustered cardiometabolic risk factors in children and adolescents.

Background Anthropometric indicators are associated with cardiometabolic risk factors (CMRF), but there is no consensus as to which indicator is the most suitable to screen for clustered CMRF. This study aimed to evaluate the utility of five anthropometric indicators to screen for clustered CMRF in children and adolescents. Methods A cross-sectional study was conducted in 1139 schoolchildren aged 6-17 years from Northeastern Brazil. Body weight, height, waist circumference (WC) and subscapular (SSF) and triceps skinfold thickness (TSF) were measured. Body mass index (BMI) and waist-to-height ratio (WHtR) were calculated. The following CMRF were evaluated: elevated total cholesterol, low high-density lipoprotein-cholesterol (HDL-C), elevated low-density lipoprotein-cholesterol (LDL-C), high triglyceride concentration, hyperglycemia and high blood pressure. The participants were categorized into no CMRF, 1 CMRF, 2 CMRF and ≥3 CMRF. Receiver operating characteristic (ROC) curves were constructed to assess the accuracy of the anthropometric indicators in predicting CMRF for age group and sex. Results Poor associations were observed between the anthropometric indicators and 1 CMRF (accuracy of 0.49-0.64). The indicators showed moderate associations with 2 CMRF (accuracy of 0.57-0.75) and ≥3 CMRF (accuracy of 0.59-0.79). In general, TSF exhibited the worst performance in predicting CMRF, followed by WHtR. The highest accuracies were observed for BMI, WC and SSF, with no significant difference between these indicators. Conclusions The routine use of BMI, WC and SSF as epidemiological screening tools for clustered CMRF in childhood and adolescence should be encouraged.

High blood pressure screening in children and adolescents from Amargosa, Bahia: usefulness of anthropometric indices of obesity. / Triagem da pressão arterial elevada em crianças e adolescentes de Amargosa, Bahia: utilidade de indicadores antropométricos de obesidade.

OBJECTIVE: To determine the predictive power of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR), and their respective cut-off points for high blood pressure (BP) screening in Brazilian children and adolescents. METHOD: Cross-sectional study conducted with 1,139 students aged 6 to 17years. Body weight, height, WC, and BP were measured. High BP was classified as systolic or diastolic ≥ 95th percentile. Receiver Operating Characteristic (ROC) curves were constructed, and the area under the curve, sensitivity, and specificity were calculated. RESULTS: The prevalence of high BP was 27.0%. Anthropometric indices showed a significant association with high BP (accuracy ranging from 0.62 - 0.81), except for WHtR among male adolescents.Sensitivity was low, regardless of the anthropometric index, gender, and age group. CONCLUSION: BMI, WC, and WHtR were associated with high BP, but the cut-off points tested showed low sensitivity. Determining specific cut-off points for each population can enable the use of anthropometric indices in high BP screening.

OBJETIVO: Determinar o poder preditivo do índice de massa corporal (IMC), perímetro da cintura (PC) e razão da cintura pela estatura (RCEst) e de seus respectivos pontos de corte para triagem de pressão arterial (PA) elevada em crianças e adolescentes brasileiros. MÉTODO: Estudo transversal realizado com1.139 escolares de 6 a 17 anos de idade. A massa corporal, a estatura, o PC e a PA foram mensurados. A PA elevada foi classificada como sistólica ou diastólica≥ percentil 95. Curvas Receiver Operating Characteristic (ROC) foram construídas e a área sob a curva, a sensibilidade e a especificidade foram calculadas. RESULTADOS: A prevalência de PA elevada foi de 27,0%. Os indicadores antropométricos apresentaram associação significativa com PA elevada (acurácia variando de 0,62 - 0,81), exceto RCEst entre adolescentes do sexo masculino.Observou-se baixa sensibilidade, independentemente do indicador antropométrico, do sexo e da faixa etária. CONCLUSÃO: OIMC, o PC e a RCEst estiveram associados a PA elevada, porém os pontos de corte testados apresentaram baixa sensibilidade. A determinação de pontos de corte específicos para cada população pode viabilizar a triagem de PA elevada por meio de indicadores antropométricos.

Waist circumference percentile curves as a screening tool to predict cardiovascular risk factors and metabolic syndrome risk in Brazilian children.

The goals of this study were to develop reference values for waist circumference (WC) in Brazilian children between 6-10 years old and to evaluate the WC performance in predicting cardiovascular risk factors and metabolic syndrome (MetS) in children. This is a population-based epidemiological cross-sectional study, in which 1,397 children participated, with a 6-10 years old probability sampling and from public and private schools in the city of Uberaba, Minas Gerais State, Brazil. WC was measured at the waist narrowest point (WC1) and at the umbilicus level (WC2). Blood samples and blood pressure were collected to determine the MetS diagnosis. There was a significant effect of age (p = 0.001), anatomical point (WC1 vs. WC2, p = 0.001) and sex-anatomical point interaction (p = 0.016) for WC. Smoothed sex- and age-specific 5th, 10th, 25th, 50th, 75th, 90th and 95th percentile curves of WC1 and WC2 were designed by the LMS method. WC was accurate to predict MetS, for all ages [area under the ROC curve (AUC) > 0.79 and p < 0.05], regardless of sex. This study presented percentile curves for WC at two anatomical points in a representative sample of Brazilian children. Furthermore, WC was shown to be a strong predictor of cardiovascular risk factors and MetS in children.

Body composition indicators in the metabolic syndrome risk prediction in 6-10-year-old children / Indicadores de composição corporal na predição de risco de síndrome metabólica em crianças de 6 a 10 anos de idade

ABSTRACT The aim of this study was to develop percentiles of body composition indicators and determine cutoff points to predict metabolic syndrome (MS) risk in 6-10-year-old children. This is a cross-sectional, population-based epidemiological study with the participation of 1480 schoolchildren aged 6-10-year. Anthropometric assessment (body mass, height, and skinfolds) and blood pressure measurement were performed in schools. The body mass index (BMI), as well as the body fat percentage (%BF), lean body mass (LBM), fat body mass (FBM), were calculated according to standardized formulas for children. Blood collection to assess the lipid and glycemic profile was also performed at school, on pre-established days and times. The MS diagnosis was determined based on changes in triglycerides, HDL-c, blood glucose, waist circumference, and blood pressure. The LMS method was used to develop the percentiles, the area under the ROC curve (AUC) to identify the accuracy of the indicators, and the sensitivity and specificity to determine the cutoff points. FBM and %BF had significantly higher values in girls, who also had lower values for %LM compared to boys (p<0.05). The indicators of body composition, BMI, FBM, and %BF were accurate in predicting the MS risk for both sex at all ages. The main indicators of body composition to predict the MS risk, in both sex, were BMI, FBM, and %BF. These findings suggest that simple anthropometric measurements, which can be performed in clinical practice, have the potential to direct non-pharmacological actions.

RESUMO Objetivou-se desenvolver percentis de indicadores de composição corporal e determinar pontos de corte para predizer o risco de síndrome metabólica (SM) em crianças de seis a 10 anos de idade. Estudo epidemiológico de corte transversal, de base populacional, com participação de 1480 escolares de seis a 10 anos de idade. A avaliação antropométrica (massa corporal, estatura e dobras cutâneas) e a aferição da pressão arterial foram realizadas nas escolas. O índice de massa corporal (IMC) bem como o percentual de gordura (%GC), percentual de massa magra (%MM), massa corporal gorda (MCG) foram calculados de acordo com fórmulas padronizadas para crianças. A coleta de sangue para avaliar o perfil lipídico e glicêmico também foi realizada na escola, em dias e horários pré-estabelecidos. O diagnóstico da SM foi determinado com base em alterações nos triglicerídeos, HDL-c, glicemia, perímetro de cintura e pressão arterial. O método LMS foi utilizado para desenvolver os percentis, a área sob a curva ROC (AUC) para identificar a acurácia dos indicadores e a sensibilidade e especificidade para determinar os pontos de corte. MCG e %GC apresentaram valores significativamente superior nas meninas e também valores inferiores para a MCM em relação aos meninos (p<0,05). Os indicadores de composição corporal, IMC, MCG e %GC apresentaram acurácia na predição do risco de SM para ambos os sexos em todas as idades. Os principais indicadores de composição corporal para predição do risco de SM, em ambos os sexos, foram o IMC, %GC e MCG. Esses achados sugerem que medidas antropométricas simples, que podem ser realizadas na prática clínica, tem potencial para direcionar ações não medicamentosas

Associação entre tempo excessivo frente à TV e índice de massa corporal em adolescentes brasileiros: uma análise de regressão quantílica da PeNSE, 2015 / Association between excessive TV viewing time and body mass index among Brazilian adolescents: quantile regression analysis of the National Student Health Survey (PeNSE), 2015

Resumo O objetivo do estudo foi investigar se tempo excessivo frente à TV está associado com índice de massa corporal (IMC), independente da atividade física (AF) e da interação com consumo de alimentos ultraprocessados (AUPs), em adolescentes brasileiros. Estudo transversal com dados de adolescentes de 13-17 anos da Pesquisa Nacional de Saúde do Escolar 2015. IMC foi o desfecho (medida direta da estatura e massa corporal) e as exposições foram tempo excessivo frente à TV (>2 h/dia), consumo diário de AUPs e AF. Regressão quantílica foi usada para testar associações e interações. Tempo excessivo frente à TV foi associado a maiores valores de IMC (ex.: 25º percentil =0,060 kg/m² versus 95º percentil =0,891 kg/m², p<0,001). Após ajuste para AF, a associação se manteve, porém, atenuada. A inclusão de AUPs no modelo potencializou a associação (ex.: 25º percentil =0,062 kg/m² versus 95º percentil =0,956 kg/m², p<0,001). Tempo excessivo frente à TV foi associado a percentis do IMC, independente da AF - ausência da AF e presença do consumo de AUPs afetam mais os percentis superiores do IMC. Ações para reduzir tempo excessivo frente à TV, consumo de AUPs e fomentar AF, são essenciais para impactar positivamente no IMC e seus reflexos na saúde dos adolescentes brasileiros.

Abstract The study aimed to investigate whether excessive TV viewing time is associated with body mass index (BMI), irrespective of physical activity (PA) and interaction with consumption of ultra-processed foods (UPFs), among Brazilian adolescents. It is a cross-sectional study with data on 13-17-year-old adolescents from the 2015 National Student Health Survey. BMI was the outcome (direct measurement of height and body mass) and exposure was excessive TV viewing time (>2 h/day), daily consumption of UPFs and PA. Quantile regression was used to test associations and interactions. Excessive screen time was associated with higher BMI values (e.g., 25th percentile =0.060 kg/m² versus 95th percentile =0.891 kg/m², p<0.001). After adjusting for PA, the association remained, however, attenuated. The inclusion of UPFs in the model potentiated the association (e.g., 25th percentile =0.062 kg/m² versus 95th percentile =0.956 kg/m², p<0.001). Excessive screen time was associated with BMI percentiles, irrespective of PA - the absence of PA and the presence of UPF consumption affect the upper BMI percentiles more. Actions to reduce excessive TV viewing time, consumption of UPFs and promoting PA are essential to positively impact BMI and its reflexes on the health of Brazilian adolescents.

Non-linear resistance training reduces inflammatory biomarkers in persons living with HIV: A randomized controlled trial.

The purpose of this study is to analyse the effect of 12 weeks of non-linear resistance training (NLRT) on anthropometry, muscle strength and inflammatory biomarkers in persons infected with human immunodeficiency virus (PIHIV). Thirty previously sedentary PIHIVs were randomized into the NLRT (n = 15) and control (CON, n = 15) groups. NLRT group were submitted to 12 weeks of training, whereas the CON group maintained their daily habits. At baseline and after 12 weeks, both groups underwent anthropometric evaluations and blood sampling for the analysis of inflammatory biomarkers. Analysis of covariance using preintervention values as covariate was performed to determine the effects of exercise on anthropometry, muscle strength, cytokines levels and T cells. Significance was set at p < 0.05. After 12 weeks of intervention, there was a decrease in subcutaneous body fat (p < .0001), neck, abdomen and waist circumferences (p < .05), waist-to-hip ratio (p = .009), blood levels of interleukin (IL)-1ß (p = .029), IL-6 (p = .005), IL-8 (p = .010), and tumour necrosis factor (TNF)-α (p = .001) and an increase in muscle strength (p < .0001), IL-10 levels (p = .030) and CD4(+) (p = .004) and CD8(+) (p < .0001) counts in the NLRT compared to CON group. Twelve weeks of NLRT promoted positive changes in the body fat, body circumferences, muscular strength and inflammatory profile in PIHIV.

Nonlinear Resistance Training Enhances the Lipid Profile and Reduces Inflammation Marker in People Living With HIV: A Randomized Clinical Trial.

BACKGROUND: Highly active antiretroviral therapy (HAART) is associated with high total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), triglyceride (TG), and C-reactive protein (CRP) levels. The natural course of the HIV infection reduces the high-density lipoprotein level (HDL-c). Thus, physical exercise plays a key role in reducing the effects of HAART and HIV. METHODS: Thirty people living with HIV (PLHIV) were randomized to the nonlinear resistance training (NLRT) and control (CON) groups. The NLRT group underwent 12 weeks of resistance training, whereas the CON group maintained usual daily activities. All volunteers underwent anthropometric, body composition, and biochemical assessments at the beginning and end of 12 weeks. RESULTS: After 12 weeks, the NLRT group had increased lean body mass (P < .0001), and a reduction in body fat mass (P < .0001) and body fat percentage (P < .0001). The levels of TC (P < .0001), LDL-c (P = .049), TG (P < .0001), and CRP (P = .004) were reduced, and the HDL-c level increased (P < .0001). CONCLUSION: Twelve weeks of NLRT causes beneficial changes in the body composition, lipid profile, and inflammation markers in PLHIV, and it can be used in this patient population.

Cluster and simultaneity of modifiable risk factors for cardiovascular diseases in adolescents of Southeast Brazil

Abstract Aim: This study aimed to evaluate the cluster of the five major modifiable risk factors for cardiovascular diseases (CVD) and their associated factors and to identify patterns of concurrency of modifiable obesogenic risk factors associated with overweight in Brazilian adolescents. Methods: A survey was conducted (2015) with 1,055 (boys, n = 475; girls, n = 580) high school (public and private schools) adolescents (14-20 years old) in a medium-sized city in Southeast Brazil. The observed prevalence ratio (O) for the expected (E) risk factors (smoking, alcohol, insufficient physical activity, sedentary behavior, and poor diet) greater than one (O/E > 1) was considered as a cluster. We use multinomial and binary logistic regressions (stratified by sex) in the analyzes. Results: Almost 30% of adolescents had three or more risk factors (no factor = 5.4%). The five risk factors tended to cluster in boys (O/E = 2.5; 95% CI = 1.6-3.5). In both sexes, smoking and alcohol consumption persisted in O/E > 1 ratio. Conclusions: Boys showed a consistent pattern of association for risk factors. Overweight was associated with pairs of obesogenic risk factors in both sexes. The results indicate the need for health interventions that consider the cluster and the simultaneity of risk factors for CVD among Brazilian youth.

Using the medicine ball throw test to predict upper limb muscle power: validity evidence / Teste do arremesso de bola medicinal para predizer potência muscular de membros superiores: evidências de validade

Abstract Muscle power is the product of muscle force and velocity, which translates into the ability to produce force in a short time interval. Periodic evaluations of strength and power, coupled with training strategies for these capacities, are of great value to athletes and multi-sports coaches, since they are key determinants for team success. Specifically, in rugby, where passing is a predominant and determinant element of sporting success, few field tests are available for assessing upper limb muscle power. The purpose of this point of view is to correct the upper limb power prediction equation previously published by our group and to highlight its concepts and applicability in sports, especially in rugby.

Resumo Potência muscular é o produto entre força e velocidade, que se traduz na capacidade de produzir força em um curto intervalo de tempo. Avaliações periódicas de força e potência, combinadas a estratégias de treinamento para essas capacidades, são de grande valor para atletas e treinadores multi-esportivos, pois são determinantes para o sucesso da equipe. Especificamente no rugby, onde o passe é elemento predominante e determinante do sucesso esportivo, poucos testes de campo estão disponíveis para avaliar força muscular de membro superior. O objetivo deste ponto de vista é corrigir a equação de predição de potência do membro superior previamente publicada pelo nosso grupo e destacar seus conceitos e aplicabilidade nos esportes, especialmente no rugby.

Food consumption, physical activity level and sedentary behavior in schoolchildren / Consumo alimentar, nível de atividade física e comportamento sedentário em escolares

Abstract Dietary intake inquiry, physical activity (PA) and sedentary behavior (SB) surveys are practical tools for identifying habits among the pediatric population; however, the results of describing these behaviors appear to be restricted to large centers. The objective was to analyze dietary intake, PA and SB level in schoolchildren. Children from 6 to 10 years old, coming from public and private schools were evaluated for anthropometry, dietary pattern, PA and SB level. A total of 1408 children (48.1% male) with a mean age of 8.05 (± 1.53) years participated in the study. Only 4.6%, 4.9% and 17.2% of children met the recommendations for fruit, milk and dairy products, respectively. 40.4% and 59.5% of the children did not meet the recommendation for soft drinks and meat consumption, respectively. More than 75% of children met the recommendation for the consumption of packaged snacks, candies and beans. There was a difference between genders only for candy consumption (p=0.003), with a higher proportion of boys meeting the recommendations. Approximately half and one third of the children complied with the recommendations for moderate to vigorous PA and SB, respectively. Risk behaviors for cardiovascular disease were observed in children, characterized by low consumption of fruits and vegetables, low levels of PA and excessive time in SB.

Resumo Inquéritos de consumo alimentar, atividade física (AF) e comportamento sedentário (CS) constituem instrumentos práticos na identificação de hábitos entre a população pediátrica. No entanto, os resultados de descrição desses comportamentos parecem estar restritos a grandes centros. Objetivou-se analisar consumo alimentar, nível de AF e CS em escolares. Crianças de seis a 10 anos de idade, oriundas de escolas públicas e privadas foram avaliadas quanto à antropometria, padrão dietético, nível de AF e de CS. Um total de 1408 crianças (48,1% do sexo masculino) com média de idade de 8,05 (± 1,53) anos participou do estudo. Apenas 4,6%, 4,9% e 17,2% das crianças atenderam às recomendações de consumo de frutas, leite e derivados e verduras/legumes, respectivamente. Não atenderam a recomendação para consumo de refrigerante e carnes 40,4% e 59,5% das crianças, respectivamente. Mais de 75% das crianças atenderam a recomendação para o consumo de salgadinho de pacote, doces e feijão. Houve diferença entre os sexos somente para o consumo de doces (p=0,003), com maior proporção de meninos a atender as recomendações. Aproximadamente, metade e um terço das crianças atenderam as recomendações para prática de AF de moderada a vigorosa intensidade e de CS, respectivamente. Comportamentos de risco para doenças cardiovasculares foram observados nas crianças, caracterizado pelo baixo consumo de frutas e verduras/legumes, baixos níveis de AF e excessivo tempo em CS.

Relationship between smartphone use and sedentary behavior: a school-based study with adolescents / Relacionamento entre smartphone e comportamento sedentário: estudo de base escolar com adolescentes

The aims of this study were a) to describe the smartphone use and sedentary behavior (SB) on typical weekdays and weekends, and b) to verify the association between smartphone use and SB among adolescents. This is a cross-sectional population school-based, which surveyed 984 students from Uberaba, Minas Gerais, in 2015. Gender-stratified analysis were performed using t-tests, Pearson's correlation (r) and multiple linear regression (ß). Girls used more smartphones than boys (weekdays: 6.58 hrs vs. 5.29 hrs, p < 0.001; weekend: 7.81 hrs vs. 6.18 hrs, p < 0.001). Both genders used more smartphones in the weekend (p < 0.001) than weekdays. SB was higher in girls than boys (weekdays: 5.34 hrs vs. 4.48 hrs, p < 0.001, weekend: 5.22 hrs vs. 4.38 hrs, p < 0.001). SB was higher for both genders at weekend (p < 0.001) than on weekdays. Correlation between SB and smartphone use ranged from weak to moderate in both genders (weekdays: boys, r = 0.30; girls, r = 0.17, p < 0.001; weekend: boys, r = 0.39; girls, r = 0.17, p < 0.001). Smartphone use was positively associated with SB during the weekdays (boys: ß = 0.25, girls: ß = 0.19, p < 0.001) and weekend (boys: ß = 0.31; girls: ß= 0.14, p < 0.001). Girls showed greater SB and smartphone use than boys, regardless if compared on weekdays or weekend. SB and smartphone were positively associated in both genders

Os objetivos deste estudo foram a) descrever o uso de smartphone e o comportamento sedentário (CS) em dias típicos de semana e final de semana (FDS) e, b) verificar a associação entre o uso de smartphone e o CS em adolescentes. Trata-se de um estudo transversal, com 984 escolares de Uberaba, Minas Gerais, conduzido em 2015. Para análises estratificadas por sexo, utilizou-se testes-t, correlação de Pearson (r) e regressão linear múltipla (ß). Moças usavam mais o smartphone que os rapazes (semana: 6,58 vs. 5,29 horas, p < 0,001; FDS: 7,81 vs. 6,18 horas, p < 0,001). Ambos os sexos usaram mais smartphone no FDS (p < 0,001). O CS foi maior nas moças que nos rapazes (semana: 5,34 vs. 4,48 horas, p < 0,001; FDS: 5,22 vs. 4,38 horas, p < 0,001). O CS foi maior no FDS, em ambos os sexos (p < 0,001). A correlação entre CS e smartphone foi de fraca a moderada em ambos os sexos (semana: rapazes, r = 0,30; moças, r = 0,17, p < 0,001; e FDS: rapazes, r = 0,39; moças, r = 0,17, p < 0,001). Uso de smartphone foi positivamente associado com CS durante a semana (rapazes: ß = 0,25; moças: ß = 0,19, p < 0,001) e FDS (rapazes: ß = 0,31; moças: ß = 0,14, p < 0,001). Moças apresentaram maior CS e uso de smartphone do que rapazes, independentemente se comparados na semana ou FDS. CS e uso de smartphones foram positivamente associados em ambos os sexos

Efeitos de um programa de Mat Pilates sobre indicadores de saúde em servidores de um hospital / Effects of a Mat Pilates program on health indicators in servers of a hospital

Objetivo:Avaliar o efeito de um programa Mat Pilates sobre a composição corporal, qualidade de vida, nível de atividade física, flexibilidade e força em servidores de um hospital universitário. Procedimentos metodológicos: Trata-se de um estudo quasi-experimental com 22 servidores, que participaram de um programa de Mat Pilates uma vez por semana, durante 20 semanas. Os servidores foram submetidos à aferição da pressão arterial, avaliação corporal, teste de força abdominal e flexibilidade, e preencheram questionários de qualidade de vida, saúde e nível de atividade física, antes e depois da intervenção. Para análise das variáveis contínuas e categóricas foram utilizados os testes t pareado e qui-quadrado, respectivamente, ao nível de significância p<0,05. Resultados: Após intervenção observou-se redução significativa do perímetro da cintura, pressão arterial sistólica e diastólica, massa corporal gorda e percentagem de gordura. Ainda, houve melhora dos níveis de atividade física, força abdominal, flexibilidade e domínios da qualidade de vida. Conclusão: Mat Pilates se mostra eficiente em melhorar parâmetros hemodinâmicos, físicos e de qualidade de vida em servidores de um hospital universitário

Objective: To evaluate the effect of a Mat Pilates program regarding the body composition, quality of life, level of physical activity, flexibility and strength in servants of a university hospital. Methodological procedures: This is a quasi-experimental study with 22 servers, who participated in a Mat Pilates program once a week for 20 weeks. The servers were submitted to blood pressure measurement, body evaluation, abdominal strength test and flexibility, and filled out questionnaires on quality of life, health and physical activity level, before and after the intervention. For the analysis of the continuous and categorical variables, paired and chi-square tests were used, respectively, at the significance level p <0.05. Results: A significant reduction in waist circumference, systolic and diastolic blood pressure, fat body mass and fat percentage were observed after intervention. Still, there was improvement of physical activity levels, abdominal strength, flexibility and domains of quality of life. Conclusion: Mat Pilates is efficient in improving hemodynamic, physical and quality of life parameters in servants of a university hospita

Triagem da pressão arterial elevada em crianças e adolescentes de Amargosa, Bahia: utilidade de indicadores antropométricos de obesidade / High blood pressure screening in children and adolescents from Amargosa, Bahia: usefulness of anthropometric indices of obesity

RESUMO: Objetivo: Determinar o poder preditivo do índice de massa corporal (IMC), perímetro da cintura (PC) e razão da cintura pela estatura (RCEst) e de seus respectivos pontos de corte para triagem de pressão arterial (PA) elevada em crianças e adolescentes brasileiros. Método: Estudo transversal realizado com1.139 escolares de 6 a 17 anos de idade. A massa corporal, a estatura, o PC e a PA foram mensurados. A PA elevada foi classificada como sistólica ou diastólica≥ percentil 95. Curvas Receiver Operating Characteristic (ROC) foram construídas e a área sob a curva, a sensibilidade e a especificidade foram calculadas. Resultados: A prevalência de PA elevada foi de 27,0%. Os indicadores antropométricos apresentaram associação significativa com PA elevada (acurácia variando de 0,62 - 0,81), exceto RCEst entre adolescentes do sexo masculino.Observou-se baixa sensibilidade, independentemente do indicador antropométrico, do sexo e da faixa etária. Conclusão: OIMC, o PC e a RCEst estiveram associados a PA elevada, porém os pontos de corte testados apresentaram baixa sensibilidade. A determinação de pontos de corte específicos para cada população pode viabilizar a triagem de PA elevada por meio de indicadores antropométricos.

ABSTRACT: Objective: To determine the predictive power of body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR), and their respective cut-off points for high blood pressure (BP) screening in Brazilian children and adolescents. Method: Cross-sectional study conducted with 1,139 students aged 6 to 17years. Body weight, height, WC, and BP were measured. High BP was classified as systolic or diastolic ≥ 95th percentile. Receiver Operating Characteristic (ROC) curves were constructed, and the area under the curve, sensitivity, and specificity were calculated. Results: The prevalence of high BP was 27.0%. Anthropometric indices showed a significant association with high BP (accuracy ranging from 0.62 - 0.81), except for WHtR among male adolescents.Sensitivity was low, regardless of the anthropometric index, gender, and age group. Conclusion: BMI, WC, and WHtR were associated with high BP, but the cut-off points tested showed low sensitivity. Determining specific cut-off points for each population can enable the use of anthropometric indices in high BP screening.