Detalles de la búsqueda
1.
RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality.
J Am Chem Soc
; 146(2): 1346-1355, 2024 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38170469
2.
Long noncoding RNA TUG1 promotes cisplatin resistance in ovarian cancer via upregulation of DNA polymerase eta.
Cancer Sci
; 115(6): 1910-1923, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38558246
3.
Hydrophobicity Tuning of Cationic Polyaspartamide Derivatives for Enhanced Antisense Oligonucleotide Delivery.
Bioconjug Chem
; 35(2): 125-131, 2024 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-38290165
4.
Systemic single administration of anti-inflammatory microRNA 146a-5p loaded in polymeric nanomedicines with active targetability attenuates neointimal hyperplasia by controlling inflammation in injured arteries in a rat model.
FASEB J
; 36(9): e22486, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35929425
5.
Dynamic Stabilization of Unit Polyion Complexes Incorporating Small Interfering RNA by Fine-Tuning of Cationic Block Length in Two-Branched Poly(ethylene glycol)-b-poly(l-lysine).
Biomacromolecules
; 23(1): 388-397, 2022 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34935361
6.
Block catiomer with flexible cationic segment enhances complexation with siRNA and the delivery performance in vitro.
Sci Technol Adv Mater
; 22(1): 850-863, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34658669
7.
Proliferation-associated long noncoding RNA, TMPO-AS1, is a potential therapeutic target for triple-negative breast cancer.
Cancer Sci
; 111(7): 2440-2450, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32437068
8.
Installation of a Thermoswitchable Hydrophobic Domain into a Unimer Polyion Complex for Enhanced Cellular Uptake of siRNA.
Bioconjug Chem
; 31(5): 1320-1326, 2020 05 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32352276
9.
Noncovalent Stabilization of Vesicular Polyion Complexes with Chemically Modified/Single-Stranded Oligonucleotides and PEG-b-guanidinylated Polypeptides for Intracavity Encapsulation of Effector Enzymes Aimed at Cooperative Gene Knockdown.
Biomacromolecules
; 21(10): 4365-4376, 2020 10 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32924444
10.
Block Copolymer Micelles in Nanomedicine Applications.
Chem Rev
; 118(14): 6844-6892, 2018 07 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-29957926
11.
Synthetic miR-143 Exhibited an Anti-Cancer Effect via the Downregulation of K-RAS Networks of Renal Cell Cancer Cells In Vitro and In Vivo.
Mol Ther
; 27(5): 1017-1027, 2019 05 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30930112
12.
Systemic Brain Delivery of Antisense Oligonucleotides across the Blood-Brain Barrier with a Glucose-Coated Polymeric Nanocarrier.
Angew Chem Int Ed Engl
; 59(21): 8173-8180, 2020 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-31995252
13.
Self-Assembly of siRNA/PEG- b-Catiomer at Integer Molar Ratio into 100 nm-Sized Vesicular Polyion Complexes (siRNAsomes) for RNAi and Codelivery of Cargo Macromolecules.
J Am Chem Soc
; 141(8): 3699-3709, 2019 02 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-30729777
14.
Tunable nonenzymatic degradability of N-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency.
Sci Technol Adv Mater
; 20(1): 105-115, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30787961
15.
Small Delivery Vehicles of siRNA for Enhanced Cancer Targeting.
Biomacromolecules
; 19(7): 2377-2390, 2018 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29864287
16.
Tuned Density of Anti-Tissue Factor Antibody Fragment onto siRNA-Loaded Polyion Complex Micelles for Optimizing Targetability into Pancreatic Cancer Cells.
Biomacromolecules
; 19(6): 2320-2329, 2018 06 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29767505
17.
Inhibition of PRDM14 expression in pancreatic cancer suppresses cancer stem-like properties and liver metastasis in mice.
Carcinogenesis
; 38(6): 638-648, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28498896
18.
Secondary-Structure-Driven Self-Assembly of Reactive Polypept(o)ides: Controlling Size, Shape, and Function of Core Cross-Linked Nanostructures.
Angew Chem Int Ed Engl
; 56(32): 9608-9613, 2017 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28544124
19.
Synthetic Polyamines to Regulate mRNA Translation through the Preservative Binding of Eukaryotic Initiation Factor 4E to the Cap Structure.
J Am Chem Soc
; 138(5): 1478-81, 2016 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26811205
20.
siRNA-Loaded Polyion Complex Micelle Decorated with Charge-Conversional Polymer Tuned to Undergo Stepwise Response to Intra-Tumoral and Intra-Endosomal pHs for Exerting Enhanced RNAi Efficacy.
Biomacromolecules
; 17(1): 246-55, 2016 Jan 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26616636