Detalles de la búsqueda
1.
Novel Tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline Chalcones Suppress Breast Carcinoma through Cell Cycle Arrests and Apoptosis.
Molecules
; 28(8)2023 Apr 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37110575
2.
Generation and Selection of Specific Aptamers Targeting Brucella Species through an Enhanced Cell-SELEX Methodology.
Int J Mol Sci
; 23(11)2022 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35682807
3.
Novel [l,2,4]triazolo[3,4-a]isoquinoline chalcones as new chemotherapeutic agents: Block IAP tyrosine kinase domain and induce both intrinsic and extrinsic pathways of apoptosis.
Invest New Drugs
; 39(1): 98-110, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32856275
4.
Computational studies and sever apoptotic bioactivity of new heterocyclic cyanoacrylamide based p-fluorophenyl and p-phenolic compounds against liver carcinoma (Hepg2).
Bioorg Chem
; 114: 105147, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34246114
5.
Bee venom and its active component Melittin synergistically potentiate the anticancer effect of Sorafenib against HepG2 cells.
Bioorg Chem
; 116: 105329, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34544028
6.
Attacking the mitochondria of colorectal carcinoma by novel 2-cyanoacrylamides linked to ethyl 1,3-diphenylpyrazole-4-carboxylates moiety as a new trend for chemotherapy.
Bioorg Chem
; 103: 104195, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32896741
7.
A novel adamantane thiadiazole derivative induces mitochondria-mediated apoptosis in lung carcinoma cell line.
Bioorg Med Chem
; 25(1): 241-253, 2017 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27847140
8.
Molecular docking simulation and anticancer assessment on human breast carcinoma cell line using novel bis(1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile) and bis(1,4-dihydropyrazolo[4',3':5,6]pyrano[2,3-b]pyridine-6-carbonitrile) derivatives.
Bioorg Chem
; 71: 19-29, 2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28143658
9.
Apoptotic induction mediated p53 mechanism and Caspase-3 activity by novel promising cyanoacrylamide derivatives in breast carcinoma.
Bioorg Chem
; 73: 43-52, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28601699
10.
Cytotoxic and antimicrobial evaluations of novel apoptotic and anti-angiogenic spiro cyclic 2-oxindole derivatives of 2-amino-tetrahydroquinolin-5-one.
Arch Pharm (Weinheim)
; 348(2): 113-24, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25664629
11.
Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma.
Sci Rep
; 13(1): 22486, 2023 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38110432
12.
Theoretical and molecular mechanistic investigations of novel (3-(furan-2-yl)pyrazol-4-yl) chalcones against lung carcinoma cell line (A549).
Naunyn Schmiedebergs Arch Pharmacol
; 396(4): 719-736, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36469109
13.
Differential expression of cystathionine beta synthase in adolescents with Down syndrome: impact on adiposity.
J Diabetes Metab Disord
; 21(2): 1491-1497, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36404855
14.
Synthesis, Cytotoxicity and Docking Simulation of Novel Annulated Dihydroisoquinoline Heterocycles.
Mini Rev Med Chem
; 20(12): 1166-1178, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32000650
15.
Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer.
Anticancer Agents Med Chem
; 20(1): 70-83, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-31696811
16.
Moringa peregrina Leaves Extracts Induce Apoptosis and Cell Cycle Arrest of Hepatocellular Carcinoma.
Biomed Res Int
; 2019: 2698570, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30713850
17.
Recent Synthetic Approaches and Biological Evaluations of Amino Hexahydroquinolines and Their Spirocyclic Structures.
Anticancer Agents Med Chem
; 19(7): 875-915, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30706793
18.
Synthesis, Cytotoxicity, Antimicrobial and Docking Simulation of Novel Pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[3,4-c] pyrimidine Derivatives.
Mini Rev Med Chem
; 19(8): 657-670, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30332953
19.
Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
Anticancer Agents Med Chem
; 19(9): 1141-1149, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30843494
20.
Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones.
Eur J Med Chem
; 143: 532-541, 2018 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29207336