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1.
Appl Opt ; 63(11): 2930-2938, 2024 Apr 10.
Artículo en Inglés | MEDLINE | ID: mdl-38856391

RESUMEN

To reduce noise in indoor visible light communication (IVLC), the Pearson correlation coefficient difference (PCCD), a denoising system combining iterative variational mode decomposition (IVMD) and multiple frequency shift keying modulation (MFSK), is proposed. Compared with VMD, the method can directly determine the optimal number of VMD modes and solve the issue of VMD penalty factor selection to some extent. The simulation results show that, when the input SNRs vary from -15 to -8d B, the proposed method can improve the output SNRs of the 2FSK signal by an average of 15.5 dB and reduce the BER by 55.8%, improve the output SNR of the 4FSK signal by an average of 13 dB, and reduce the BER by 54.4%. The proposed method can also effectively suppress noise interference in real IVLC experiments at a distance of 1 m. In addition, the IVMD-MFSK denoising system can be applied to denoise all frequency-modulated signals with high applicability.

2.
Opt Express ; 31(15): 25207-25219, 2023 Jul 17.
Artículo en Inglés | MEDLINE | ID: mdl-37475331

RESUMEN

We propose, what we believe to be, a novel method for high temperature sensing calibration based on the mechanism of alterable interferential fineness in Bragg hollow core fiber (BHCF). To verify the proof-of-concept, the fabricated sensing structure is sandwiched by two sections with different length of BHCF. Two interferential fineness fringes dominate the transmission spectrum, where the high-fineness fringes formed by anti-resonant reflecting optical waveguide (ARROW) plays the role for high temperature measurement. Meanwhile, the low-fineness fringes induced by short Fabry-Perot (F-P) cavity are exploited as temperature calibration. The experimental results show that the ARROW mechanism-based temperature sensitivity can reach 26.03 pm/°C, and the intrinsic temperature sensitivity of BHCF is 1.02 pm/°C. Here, the relatively lower magnitude of the temperature sensitivity is considered as the standard value since it merely relies on the material properties of silicon. Additionally, a large dynamic temperature range from 100 °C to 800 °C presents linear response of the proposed sensing structure, which may shine the light on the sensing applications in the harsh environment.

3.
Lasers Med Sci ; 38(1): 44, 2023 Jan 19.
Artículo en Inglés | MEDLINE | ID: mdl-36656398

RESUMEN

To compare the safety and efficacy of en bloc resection of non-muscle-invasive bladder cancer (NMIBC) using a 1470-/980-nm dual-wavelength laser (DwLRBT) compared to the gold standard, transurethral resection (TURBT). The study group included 251 patients with a confirmed diagnosis of NMIBC, 97 in the DwLRBT group and 154 in the TURBT group. Clinical characteristics, complications, and recurrence-free survival were compared between the two groups. There were no differences between the two groups with regard to age, sex, mean tumor size, mean tumor number, tumor location, risk, fever, and reoperation. Compared to TURBT, DwLRBT was associated with a shorter hospitalization time (mean±standard deviation: 5.81±1.48 days vs. 4.96±1.32, respectively, p=0.001), shorter catheterization time (4.98±1.47 vs. 4.20±1.48 days, respectively; p=0.035), and smaller volume of intraoperative bleeding (8.43±6.21 ml vs. 6.15±5.08, respectively; p=0.003). Recurrence-free survival (RFS) was better for DwLRBT than TURBT in the overall cohort (hazard ratio [HR], 0.4323; 95% confidence interval [CI], 0.2852-0.6554; p=0.0004) and for the following subgroups and tumor types: intermediate-risk (HR, 0.2654; 95%CI, 0.1020-0.6904; p=0.0245) and high-risk (HR, 0.4461; 95% CI, 0.2778-0.7162; p=0.0027) groups; and for pedunculate bladder tumors (HR, 0.4158; 95%CI, 0.2401-0.7202; p=0.0063), single bladder tumors (HR, 0.4136; 95%CI, 0.2376-0.7293; p=0.0072), and multiple bladder tumors (HR, 0.2727; 95%CI, 0.1408-0.5282; p=0.0014). DwLRBT is associated with better operative and postoperative outcomes, including, importantly, a longer RFS, compared to TURBT.


Asunto(s)
Neoplasias Vesicales sin Invasión Muscular , Neoplasias de la Vejiga Urinaria , Humanos , Estudios Retrospectivos , Resección Transuretral de la Vejiga , Neoplasias de la Vejiga Urinaria/cirugía , Neoplasias de la Vejiga Urinaria/patología , Rayos Láser , Recurrencia Local de Neoplasia/patología , Invasividad Neoplásica
4.
Opt Express ; 30(21): 37526-37535, 2022 Oct 10.
Artículo en Inglés | MEDLINE | ID: mdl-36258340

RESUMEN

Ultrahigh-order optical orbital angular momentum (OAM) states of the identification over ±270 orders are implemented by annular phase grating (APG) and Gaussian beams with different wavelengths. Particularly, the far-field diffraction intensity patterns feature the spiral stripes instead of Hermitian-Gaussian (HG)-like fringes. It's worth noting that the spiral stripes present uniform distribution, thus the order of OAM states can be intuitively acquired. More specifically, the OAM states can be confirmed from the total amount and rotating direction of the spiral stripes. Compared with traditional methods, the propose scheme contributes to the perfect-distributed and sharper spiral stripes. Moreover, it also makes an easier observation of the patterns in the CCD camera with limited imaging targets. In our experimental setup, the optical filter is removed and the APG parameters are not strictly required. Therefore, the propose optical transmission system is equipped with the advantages of efficiency, robustness and low cost, which paves a promising way for the communication capacity enhancement.

5.
Chemphyschem ; 23(8): e202100912, 2022 04 20.
Artículo en Inglés | MEDLINE | ID: mdl-35191573

RESUMEN

Attaching stable radicals to organic chromophores is an effective method to enhance the intersystem crossing (ISC) of the chromophores. Herein we prepared perylene-oxoverdazyl dyads either by directly connecting the two units or using an intervening phenyl spacer. We investigated the effect of the radical on the photophysical properties of perylene and observed strong fluorescence quenching due to radical enhanced ISC (REISC). Compared with a previously reported perylene-fused nitroxide radical compound (triplet lifetime, τT =0.1 µs), these new adducts show a longer-lived triplet excited state (τT =9.5 µs). Based on the singlet oxygen quantum yield (ΦΔ =7 %) and study of the triplet state, we propose that the radical enhanced internal conversion also plays a role in the relaxation of the excited state. Femtosecond fluorescence up-conversion indicates a fast decay of the excited state (<1.0 ps), suggesting a strong spin-spin exchange interaction between the two units. Femtosecond transient absorption (fs-TA) spectra confirmed direct triplet state population (within 0.5 ps). Interestingly, by fs-TA spectra, we observed the interconversion of the two states (D1 ↔Q1 ) at ∼80 ps time scale. Time-resolved electron paramagnetic resonance (TREPR) spectral study confirmed the formation of the quartet sate. We observed triplet and quartet states simultaneously with weights of 0.7 and 0.3, respectively. This is attributed to two different conformations of the molecule at excited state. DFT computations showed that the interaction between the radical and the chromophore is ferromagnetic (J>0, 0.05∼0.10 eV).


Asunto(s)
Perileno , Espectroscopía de Resonancia por Spin del Electrón , Conformación Molecular , Oxígeno Singlete/química
6.
Molecules ; 27(16)2022 Aug 09.
Artículo en Inglés | MEDLINE | ID: mdl-36014308

RESUMEN

The ultrafast dynamics of triplet excitons and polarons in hexaphenyl film was investigated by time-resolved fluorescence and femtosecond transient absorption techniques under various excitation photon energies. Two distinct pathways of triplet formation were clearly observed. Long-lived triplet states are populated within 4.5 ps via singlet fission-intersystem crossing, while the short-lived triplet states (1.5 ns) are generated via singlet fission from vibrational electronic states. In the meantime, polarons were formed from hot excitons on a timescale of <30 fs and recombined in ultrafast lifetime (0.37 ps). In addition, the characterization of hexaphenyl film suggests the morphologies of crystal and aggregate to wide applications in organic electronic devices. The present study provides a universally applicable film fabrication in hexaphenyl system towards future singlet fission-based solar cells.

7.
J Chem Phys ; 155(19): 191102, 2021 Nov 21.
Artículo en Inglés | MEDLINE | ID: mdl-34800965

RESUMEN

A long 0.9 ps lifetime of the upper excited singlet state in perylene is resolved by femtosecond pump-probe measurements under ultraviolet (4.96 eV) excitation and further validated by theoretical simulations of transient absorption kinetics. This finding prompts exploration and development of novel perylene-based materials for upper excited state photochemistry applications.

8.
Opt Express ; 28(3): 4216-4224, 2020 Feb 03.
Artículo en Inglés | MEDLINE | ID: mdl-32122078

RESUMEN

Rapid progress in real-time spectroscopy uncovers the spatio-spectral scenarios of ultrashort pulses in dissipative systems. Varieties of transient soliton dynamics on different timescales have been revealed. Here, we report on an experimental observation of stationary and pulsating vector dissipative solitons in a nonlinear multimode interference (NL-MMI) based fiber laser with net normal dispersion. Polarization non-discrimination of the NL-MMI mode-locking facilitates the dissipative soliton trapping process. Two orthogonally polarized components are coupled together through oppositely shifting their central frequencies to form the group-velocity-locked vector dissipative solitons (GVLVDSs). Dispersive Fourier transform (DFT) based polarization resolved measurement enables insights into the transient polarization dynamics and the long-term evolution. Particularly, both stationary and pulsating GVLVDSs are obtained with appropriate parameter settings. It is found that the quasi-stationary pulsating manner is accompanied with recurrent spectral breathing and energy oscillation; the two orthogonally polarized components possess synchronous pulsating manners due to the cross-phase modulation induced trapping mechanism and the similar formation process. Additionally, chaotic pulsation is also captured in sense that the spectra cannot recover to their original profiles despite of the harmonic energy oscillation. All these findings can enhance our understanding towards soliton pulsation with the freedom of vectorial degree.

9.
Opt Lett ; 45(6): 1551-1554, 2020 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-32164014

RESUMEN

Recent progress in real-time spectral interferometry enables access to the internal dynamics of optical multisoliton complexes. Here, we report on the first, to the best of our knowledge, experimental observation of shaking soliton molecules by means of the dispersive Fourier transform technique. Beyond the simplex vibrating soliton pairs, multiple oscillatory motions can jointly involve in the internal dynamics, reminiscent of the shaking soliton pairs. Both quasi-periodically and chaotically evolving phase oscillations are approached in the sense of different oscillatory frequencies. In addition, the shaking soliton pair combined with sliding phase dynamics is also observed, and is interpreted as the superposition of two different internal motions. All of these results shed new light on the internal dynamics of soliton molecules with higher degrees of freedom, as well as enrich the framework toward multisoliton complexes.

10.
Opt Lett ; 45(4): 1017-1020, 2020 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-32058530

RESUMEN

The performance of sensors, including optical fiber sensors, is commonly limited by the tradeoff between a large dynamic range and a high resolution. In this Letter, in order to optimize both, we propose an inline multimode interferometer sensor based on a suspended-core microstructured optical fiber. Due to the existence of multiple pairs of mode interferences, the transmission spectrum of the interferometer consists of dense fringes modulated by a lower envelope. Since these mode interferences take place in the uniform material with the same length, the dense fringes and the lower envelope have an identical sensing response without crosstalk. Hence, the sensor integrates the large dynamic range of the lower envelope and the high resolution of the dense fringes. Strain-sensing performance is investigated to validate the characteristic of the large dynamic range and the high resolution of the proposed sensor. The dynamic range, theoretically 0-9200 µÉ›, is 12 times larger than for the dense fringes, and the resolution is 17.5 times higher than for the lower envelope.

11.
Opt Express ; 27(21): 30629-30638, 2019 Oct 14.
Artículo en Inglés | MEDLINE | ID: mdl-31684307

RESUMEN

Recent progress in designing optimized microstructured optical fiber spreads an application scenario of optical fiber sensing. Here, we investigate the bending measurement based on a specially designed hollow core photonic crystal fiber (HC-PCF). Numerical simulation indicates that the bending sensitivity is mainly determined by the diameter of the hollow core and also depends on the coupled modes. Experimentally, a direction-independent bending sensor is fabricated by sandwiching a segment of specially designed HC-PCF into two segments of single mode fibers. The bending sensitivity of our device is improved 10 times by increasing the diameter of the hollow core. Bending measurement is validated at two orthogonal planes. The maximum sensitivity up to 2.8 nm/deg is obtained at 14° bending angle. Additionally, a low thermal sensitivity of 2.5 pm/°C is observed from 18°C to 1000°C. The sensor is robust, easy to fabricate and cost effective, which is promising in the field of small-angle bending measurement under a large temperature range.

12.
Opt Express ; 27(17): 24300-24310, 2019 Aug 19.
Artículo en Inglés | MEDLINE | ID: mdl-31510321

RESUMEN

In this work we demonstrate a low-frequency acoustic sensor structure based on extrinsic Fabry-Pérot interferometer (EFPI) cavity. The cavity is fabricated through micromachining techniques in a square silicon substrate with 4 mm side length and 400 µm thickness, which gives the sensor relative compact size. In the assembling process of the lead-in fiber, a D-shaped ceramic ferrule is designed to achieve the open cavity structure, which can balance the environmental pressure inside and outside the cavity and thus giving the sensor potentials of resisting strong pressure variations in some harsh application environments. Experimentally, sensor response to low-frequency acoustic waves from 0.1 Hz to 250 Hz is measured and demonstrated. A flat response region between 0.5 Hz to 250 Hz with sensitivity fluctuation of 0.8 dB is realized. Pressure resistant test of 25 MPa is also conducted on the sensor and exhibited to prove the function of the open cavity structure.

13.
Opt Lett ; 44(21): 5382-5385, 2019 Nov 01.
Artículo en Inglés | MEDLINE | ID: mdl-31675012

RESUMEN

A Bragg labeled wavelength (BLW) employed to the sensitivity calibration in an interference pattern has been proposed and experimentally demonstrated. According to the critical condition of Fabry-Perot (FP) interference and the antiresonant (AR) effect, the length of hollow core fiber (HCF) is artificially controlled to form a FP microcavity by collapsed fusion splicing. Dual-spectral features of the BLW and inline multimode interference (IMMI) dominate the transmission spectrum of the collapsed Bragg HCF (BHCF). The location of the BLW remains unchanged once the air-core diameter is selected. Sensing performance is investigated to validate the calibration function of the proposed BHCF. In particular, the temperature sensitivity of the BLW and multimode interference are 12.8 pm/°C and 87.1 pm/°C, respectively, corresponding to the reference sensitivity induced by the Bragg structure and the measurement sensitivity of the IMMI. All these findings highlight the calibration of HCF-based interferometric sensors in practical applications.

14.
Chemistry ; 25(19): 5028-5035, 2019 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-30710376

RESUMEN

Fundamental photocatalytic limitations of solar CO2 reduction remain due to low efficiency, serious charge recombination, and short lifetime of catalysts. Herein, two-dimensional graphitic carbon nitride nanosheets with nitrogen vacancies (g-C3 Nx ) located at both three-coordinate N atoms and uncondensed terminal NHx species were prepared by one-step tartaric acid-assistant thermal polymerization of dicyandiamide. Transient absorption spectra revealed that the defects in g-C3 N4 act as trapped states of charges to result in prolonged lifetimes of photoexcited charge carriers. Time-resolved photoluminescence spectroscopy revealed that the faster decay of charges is due to the decreased interlayer stacking distance in g-C3 Nx in favor of hopping transition and mobility of charge carriers to the surface of the material. Owing to the synergic virtues of strong visible-light absorption, large surface area, and efficient charge separation, the g-C3 Nx nanosheets with negligible loss after 15 h of photocatalysis exhibited a CO evolution rate of 56.9 µmol g-1 h-1 under visible-light irradiation, which is roughly eight times higher than that of pristine g-C3 N4 . This work presents the role of defects in modulating light absorption and charge separation, which opens an avenue to robust solar-energy conversion performance.

15.
J Cell Biochem ; 119(7): 5163-5174, 2018 07.
Artículo en Inglés | MEDLINE | ID: mdl-29227586

RESUMEN

Clear cell renal cell carcinoma (ccRCC) is a common genitourinary malignancy with high mortality. However, the molecular pathogenesis of ccRCC remains unclear and effective biomarkers for daily practice are still limited. Thus, we aimed to identify the potential crucial genes and pathways associated with carcinogenesis of ccRCC and further analyze the molecular mechanisms implicated in tumorigenesis. In the present study, expression profiles GSE 66270, GSE 53757, GSE 36895, and GSE 76351 were downloaded from GEO database, including 244 matched primary and adjacent normal tissues, furthermore, the level 3 RNAseq dataset (RNAseqV2 RSEM) of KIRC was also downloaded from The Cancer Genome Atlas (TCGA), which consist of 529 ccRCC tumors and 72 normal tissues. Then, differentially expressed genes (DEGs) and pathway enrichment were analyzed by using R software. A total of 129 up- and 123 down-regulated genes were identified, which were aberrantly expressed both in GEO and TCGA data. Second, Gene ontology (GO) analyses revealed that most of the DEGs were significantly enriched in integral component of membrane, extracellular exosome, plasma membrane, cell adhesion, and receptor binding. Signaling pathway analyses indicated that DEGs had common pathways in signal transduction, metabolism, and immune system. Third, hub genes were identified with protein-protein interaction (PPI) network, including PTPRC, TGFB1, EGF, MYC, ITGB2, CTSS, FN1, CCL5, KNG1, and CD86. Additionally, sub-networks analyse was also performed by using MCODE plugin. In conclusion, the novel DEGs and pathways in ccRCC identified in this study may provide new insight into the underlying molecular mechanisms that facilitates RCC carcinogenesis.


Asunto(s)
Carcinoma de Células Renales/metabolismo , Carcinoma de Células Renales/genética , Biología Computacional , Perfilación de la Expresión Génica , Regulación Neoplásica de la Expresión Génica/genética , Regulación Neoplásica de la Expresión Génica/fisiología , Ontología de Genes , Redes Reguladoras de Genes , Humanos , Mapas de Interacción de Proteínas
16.
Opt Express ; 26(16): 20758-20767, 2018 Aug 06.
Artículo en Inglés | MEDLINE | ID: mdl-30119381

RESUMEN

An ultra-wideband fiber optic acoustic sensor based on graphene diaphragm with a thickness of 10nm has been proposed and experimentally demonstrated. The two reflectors of the extrinsic Fabry-Perot interferometer is consist of fiber endface and graphene diaphragm, and the cavity is like a horn-shape. The radius of the effective area of the ultrathin graphene diaphragm is 1mm. Attributed to the strong van der Waals force between the diaphragm and the ceramic ferrule, the sensor head can be applied not only in the air but also underwater. Experimental results illustrate that ultra-wideband frequency response is from 5Hz to 0.8MHz, covering the range from infrasound to ultrasound. The noise-limited minimum detectable pressure level of 0.77Pa/Hz1/2@5Hz and 33.97µPa/Hz1/2@10kHz can be achieved, and the applied sound pressure is 114dB and 65.8dB, respectively. The fiber optic acoustic sensor may have a great potential in seismic wave monitoring, photoacoustic spectroscopy and photoacoustic imaging application due to its compact structure, simple manufacturing, and low cost.

17.
Opt Express ; 26(14): 18341-18350, 2018 Jul 09.
Artículo en Inglés | MEDLINE | ID: mdl-30114015

RESUMEN

In this paper, a high resolution and large dynamic range fiber optic temperature sensor without measurement crosstalk has been proposed. Two combinational mechanisms of anti-resonant reflecting optical waveguide and inline Mach-Zehnder interference structure are integrated in single hole twin eccentric cores fiber. The dual-effect composite spectrum is consist of several dominant resonant wavelengths and comb pattern, which are corresponding to the two above-mentioned mechanisms. Gauss fit and fast Fourier transform filtering are used for extracting the resonant wavelengths and comb spectrum, respectively. Accordingly, the temperature sensitivity of 42.18pm/°C and 2.057nm/°C are achieved by tracking the coherent decrease point. The lower sensitivity can guarantee a large dynamic range, while the higher one will contribute to the enhanced resolution. Therefore, the temperature monitoring is the combination of large dynamic range and enhanced resolution. Moreover, the size of the ultracompact sensor is only 950µm, which has a great potential for engineering applications.

18.
Opt Express ; 25(13): 14389-14396, 2017 Jun 26.
Artículo en Inglés | MEDLINE | ID: mdl-28789025

RESUMEN

We report and demonstrate a highly-sensitive refractive index (RI) sensor based on a linear-cavity dual-wavelength erbium-doped fiber laser (DWEDFL). The optical spectrum of the laser varies as the external environmental RI changes from 1.3 to 1.335. The DWEDFL has a linear-cavity configuration with two fiber Bragg gratings (FBGs) with central wavelengths < 1 nm apart. Since both FBGs share the same EDF gain medium, gain competition occurs in the cavity. Optical loss of one wavelength can be introduced by immersing the sensing component, a 15 mm micro-fiber (MF), in a solution under test. Experimental results demonstrate a high sensitivity of -231.1 dB/RIU (refractive index unit) and 42.6 dB/RIU in the range from 1.300 to 1.335. The relative power change at the two FBG wavelengths reveals a higher sensitivity of -273.7 dB/RIU with better stability due to reduced light source jitter and external perturbation. Due to its high sensitivity and simple structure, the dual wavelengths gain competition RI sensor has potential applications in chemical and biochemical sensing fields.

19.
Opt Express ; 25(4): 4429-4437, 2017 Feb 20.
Artículo en Inglés | MEDLINE | ID: mdl-28241645

RESUMEN

In this article, we propose an interrogation method of fiber acoustic sensor to recover the time-domain signal from the sensor spectrum. The optical spectrum of the sensor will show a ripple waveform when responding to acoustic signal due to the scanning process in a certain wavelength range. The reason behind this phenomenon is the dynamic variation of the sensor spectrum while the intensity of different wavelength is acquired at different time in a scanning period. The frequency components can be extracted from the ripple spectrum assisted by the wavelength scanning speed. The signal is able to be recovered by differential between the ripple spectrum and its self-fitted curve. The differential process can eliminate the interference caused by environmental perturbations such as temperature or refractive index (RI), etc. The proposed method is appropriate for fiber acoustic sensors based on gratings or interferometers. A long period grating (LPG) is adopted as an acoustic sensor head to prove the feasibility of the interrogation method in experiment. The ability to compensate the environmental fluctuations is also demonstrated.

20.
Opt Express ; 25(21): 25612-25624, 2017 Oct 16.
Artículo en Inglés | MEDLINE | ID: mdl-29041226

RESUMEN

A novel scheme is proposed to mitigate the atmospheric turbulence effect in free space optical (FSO) communication employing orbital angular momentum (OAM) multiplexing. In this scheme, the Gaussian beam is used as an auxiliary light with a common-path to obtain the distortion information caused by atmospheric turbulence. After turbulence, the heterodyne coherent detection technology is demonstrated to realize the turbulence mitigation. With the same turbulence distortion, the OAM beams and the Gaussian beam are respectively utilized as the signal light and the local oscillation light. Then the turbulence distortion is counteracted to a large extent. Meanwhile, a phase matching method is proposed to select the specific OAM mode. The discrimination between the neighboring OAM modes is obviously improved by detecting the output photocurrent. Moreover, two methods of beam size adjustment have been analyzed to achieve better performance for turbulence mitigation. Numerical results show that the system bit error rate (BER) can reach 10-5 under strong turbulence in simulation situation.

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