Seven-Week Accommodating Resistance Training Improves Wingate Peak Power But Not Muscular Strength or Endurance in Strength-Trained Females.

ABSTRACT: Parten, AL, Barker, GA, O'Neal, EK, and Waldman, HS. Seven-week accommodating resistance training improves Wingate peak power but not muscular strength or endurance in strength-trained females. J Strength Cond Res 37(9): 1789-1794, 2023-Accommodating resistance (AR) is a training technique that includes attaching elastic bands or chains to a loaded barbell to alter the resistance profile throughout the barbell movement. This study was the first to quantify the effects of AR versus a traditional resistance (TR) training program on changes in strength and power profiles in a trained female cohort. Resistance-trained (training history: 2.4 ± 1.4 years) females (age: 22.1 ± 3.0 years) completed baseline and postintervention tasks which included 1 repetition maximum (1RM) testing in the back squat (BS) and bench press (BP), a repetitions to failure in the BP (60% of 1RM), and 1 30-s Wingate test. After baseline testing, subjects were stratified (based on relative strength) into either the AR ( n = 9) or TR ( n = 10) group and then completed a supervised, 7-week training intervention. Both groups improved their 1RM in both lifts, but no statistical differences were found between groups in 1RM for BS, BP, or BP to failure ( p > 0.05). However, the AR group increased Wingate peak power (837 ± 221 to 901 ± 215 W; p = 0.04), whereas TR (868 ± 244 to 8,343 ± 182 W; p = 0.47) did not. This study supports AR with lighter relative barbell load incurs similar strength adaptations as TR. For coaches training athletes concerned with power, AR may be advantageous for improving rate of force development as demonstrated by large increases in peak Wingate power.

Assessment of Metabolic Flexibility by Substrate Oxidation Responses and Blood Lactate in Women Expressing Varying Levels of Aerobic Fitness and Body Fat.

ABSTRACT: Waldman, HS, Bryant, AR, Knight, SN, Killen, LG, Davis, BA, Robinson, MA, and O'Neal, EK. Assessment of metabolic flexibility by substrate oxidation responses and blood lactate in women expressing varying levels of aerobic fitness and body fat. J Strength Cond Res 37(3): 581-588, 2023-Collection of substrate oxidation responses during exercise is proposed as a noninvasive means for assessing metabolic flexibility in male subjects. However, because of hormonal and metabolic differences between sexes, this method may not be applicable to female subjects. This study assessed metabolic flexibility through indirect calorimetry across female subjects with different maximal oxidative capacities. Thirty-eight (18-45 years) eumenorrheic female subjects were stratified ( p < 0.05) based on V̇ o2 peak (mL·kg -1 ·min -1 ) into (1) endurance-trained (ET, n = 12, 42.6 ± 5.3), (2) recreationally active (RA, n = 13, 32.3 ± 1.6), or (3) overweight female subjects (OW, n = 13, 21.0 ± 4.0). Subjects completed the same 5-stage graded exercise test with intensities of 30, 45, 60, 75, and 90 W. Lactate [La - ], carbohydrate (CHOox), and fat (FATox) oxidation rates were assessed during the last min of each 5-minute stage. Subjects then cycled to exhaustion to determine V̇ o2 peak. Endurance-trained and RA female subjects expressed significantly ( p ≤ 0.05) higher absolute rates and rates scaled to fat-free mass of CHOox and FATox compared with OW female subjects during multiple stages. [La - ] failed to consistently differentiate the 3 groups with higher [La - ] for OW only found during stage 4; however, RER differed by 0.09 units or more at each stage for OW vs. ET. It seems that RER was more sensitive to cohort characteristics than [La - ] contrasting recent findings in male cohorts. In conclusion, indirect calorimetry is a practical and noninvasive method for assessing metabolic flexibility in eumenorrheic female subjects of varying aerobic fitness levels.

A Self-Selected 16:8 Time-Restricted Eating Protocol Improves Fat Oxidation Rates, Markers of Cardiometabolic Health, and 10-km Cycling Performance in Middle-Age Male Cyclists.

ABSTRACT: Witt, CR, Grozier, CD, Killen, LG, Renfroe, LG, O'Neal, EK, and Waldman, HS. A self-selected 16:8 time-restricted eating protocol improves fat oxidation rates, markers of cardiometabolic health, and 10-km cycling performance in middle-age male cyclists. J Strength Cond Res 37(5): 1117-1123, 2023-The purpose of this study was to assess the impact of 4 weeks, 16:8 time restricted eating (TRE) on markers of metabolic health and 10-km time trial (TT) performance in middle-age male cyclists. Subjects ( n = 12; age, 40-60 years; V̇ o2 peak, 41.8 ± 5.6 ml·kg -1 ·min -1 ) consisting of individuals following a habitual Western diet completed a familiarization and 2 experimental trials [PRE] and [POST]. Following habitual Western diet without TRE, anthropometric measures were assessed, followed by completion of a graded exercise test and 10-km TT. Subjects then adhered to a 4-week TRE protocol where all calories had to be consumed within a self-selected 8-hour window and then returned for repeat testing. Although self-reported caloric intake did not statistically change PRE to POST, body mass (PRE, 83.2 ± 13.4 vs. POST, 80.7 ± 12.6 kg), fat mass (∼2.5 kg), and blood pressure (systolic, 8 mm Hg; diastolic, 4 mm Hg) were all significantly lower POST (all p < 0.05), with no changes in fat-free mass. Furthermore, fat oxidation significantly increased (PRE, 0.36 ± 0.03 vs. POST, 0.42 ± 0.03 g·min -1 ; p = 0.04) following the TRE intervention and 10-km TT performance improved by ∼2 minutes POST (PRE, 29.7 ± 7.3 vs. POST, 27.4 ± 5.5 minutes; p = 0.02). Overall, our data demonstrated that middle-age male cyclists adhering to a 4-week TRE protocol can improve their body composition profile and 10-km TT performance without detriments to fat-free mass.

Retrospective and Contemporary Predictors of National Collegiate Athletic Association Division I Cross-Country Performance Are Sex Specific.

ABSTRACT: Carder, MJ, Scudamore, EM, Savanna, KN, Pribyslavska, V, Bowling, LR, and O'Neal, EK. Retrospective and contemporary predictors of National Collegiate Athletic Association Division I cross-country performance are sex specific. J Strength Cond Res 37(11): 2267-2272, 2023-The purpose of this study was to identify National Collegiate Athletic Association (NCAA) Division I cross-country (XC) performance potential using laboratory-based and field-based parameters and retrospective high school (HS) personal best (PB) data at various distances of current collegiate XC runners. Fifteen female and 17 male NCAA XC runners provided their PB for 5-km (women) and 8-km (men) distances from the previous season. Bivariate correlation and stepwise and hierarchical regression modeling were used to predict XC performance. Single squat jump height and multijump reactive strength index displayed r < 0.27 for both sexes, suggesting lower-body power is a poor predictor of XC performance or masked by other factors of greater importance. Triceps skinfold thickness approached significance (r = 0.43; p = 0.09) for men but was unrelated to women's performance (r = -0.05; p = 0.86). HS XC PB neared significance (r = 0.55, p = 0.054), but no other single or combination of variables reached significance for female runners. Aerobic capacity displayed a moderate to strong relationship (r = 0.65) for male runners. High school 3,200-m PB for men produced a robust prediction capacity (r = 0.85; p = 0.005, SEE = ± 0.65 minutes), and predicted 8-km PB within 30 seconds for approximately two-thirds of runners. These outcomes suggest when recruiting HS or transfer athletes, male and female XC runners should not be recruited on the same factors. Women's XC PB is more difficult to predict, but skinfold thickness was statistically the least valuable predictor of all factors.

A 3-Week, Low-Carbohydrate, High-Fat Diet Improves Multiple Serum Inflammatory Markers in Endurance-Trained Males.

ABSTRACT: Waldman, HS, Heatherly, AJ, Killen, LG, Hollingsworth, A, Koh, Y, and O'Neal, EK. A three-week, low-carbohydrate, high-fat diet improves multiple serum inflammatory markers in endurance-trained males. J Strength Cond Res 36(9): 2502-2508, 2022-This study examined the effects of a low-carbohydrate, high-fat diet (LCHF) on inflammatory marker responses in middle-aged endurance athletes. Eight male runners maintained their habitual mixed diet (HMD) in the first phase of the study before switching to a noncalorically restricted LCHF diet (∼70% of kcals from fat; carbohydrate <50 g) for 3 weeks. Subjects completed a 50-minute fixed pace treadmill running protocol in a hot environment, followed by a 5-km outdoor time trial. Fasting serum samples were collected immediately after exercise and heat stress restriction, and again 24 hours after the exercise/heat stressor. Thirty inflammation markers were assessed using the multiplex flow immunoassay technique. Seven markers (BAFF/TNFSF-13, sCD30/TNFRSF8, sCD163, Chitinase3-like1, gp130SIL-6Rß, sTNFR-1, and sTNFR-2) reached statistical significance ( p < 0.05) favoring LCHF before exercise, and sCD30/TNFRSF8 favored ( p < 0.05) LCHF before (HMD = 459 ± 111; LCHF = 296 ± 100) and after (HMD = 385 ± 104; LCHF = 285 ± 104 pg·ml -1 ) exercise. Although the current dietary intervention was short in duration, LCHF seems to offer some protection against multiple chronic inflammation markers for physically active men between ages 30 and 50 years.

Effects of Magnesium Supplementation on Muscle Soreness and Performance.

ABSTRACT: Reno, AM, Green, M, Killen, LG, O'Neal, EK, Pritchett, K, and Hanson, Z. Effects of magnesium supplementation on muscle soreness and performance. J Strength Cond Res 36(8): 2198-2203, 2022-This double-blind, between-group study examined effects of magnesium (Mg) supplementation (350 mg·d -1 , 10 days) on muscle soreness and performance. College-aged male ( n = 9) and female ( n = 13) subjects completed baseline and posttreatment eccentric bench press sessions inducing fatigue/soreness followed by performance sessions (total volume and repetitions to failure [RTF] [65, 75, and 85% of 1 repetition maximum]) 48 hours later with perceptual measures. Subjects estimated soreness using a Delayed Onset of Muscle Soreness scale by striking a vertical line on a 6-cm horizontal line (at 24, 36, and 48 hours post trial) from 0-no soreness to 6-intolerable soreness. Results are presented as means ± SD (alpha ≤0.05). Mg significantly reduced (∼1-2 units lower on a 6-point scale) muscle soreness from the baseline eccentric to postintervention trial 24, 36, and 48 hours with no significant change for placebo (Pla) group. Performance approached significance for total RTF ( p = 0.06) and 65 and 75% RTF ( p = 0.08) (Mg vs. Pla). Perceptual responses for session rating of perceived exertion and acute rating of perceived exertion were significant for Mg (5.1 ± 2.4 to 4.1 ± 2.0) vs. Pla (5.0 ± 1.8 to 5.5 ± 1.6). Perceived recovery after supplementation was improved vs. baseline for Mg (5.4 ± 2.2 to 7.5 ± 2.3) but not for Pla (6.2 ± 2.4 to 7.2 ± 3.3). Results show significantly reduced muscle soreness, session rating of perceived exertion, acute rating of perceived exertion, and improved perceived recovery after Mg (vs. Pla) supplementation and some evidence for positive performance impact.

Effects of 2.4 kg of Proximal External Loading on 5-km Running Performance.

ABSTRACT: Sharp, DW, Swain, JC, Boy, TG, Killen, LG, Green, JM, and O'Neal, EK. Effects of 2.4 kg of proximal external loading on 5-km running performance. J Strength Cond Res 36(7): 1833-1838, 2022-Racing weight is a popular topic in the running community. This study examined effects of modest loading via a ∼2.4-kg soft and malleable weighted compression garment on overground running performance. Former and current collegiate cross-country runners (5 women and 6 men) completed 2 outdoor, solo road course runs 7 days apart on a familiar training route. During the first run (CON) subjects ran as closely as possible to their goal pace for a "hard speed day" workout based on predetermined paces according to current training level. During a subsequent run, subjects attempted to match their pace with aid from global positioning system watches and splits verbally announced on the course while wearing the weighted compression garment (LOAD). Metabolic data was later assessed during 5-minute running bouts on a treadmill with CON and LOAD conditions at subject's CON run pace. LOAD was slower (p < 0.01) at the 1.6-km mark (6:03 ± 0:37 vs. 6:13 ± 0:40) and finish (18:29 ± 2:06 vs. 19:15 ± 2:16). There was no differentiation (p > 0.05) between V̇o2 (CON 3.47 ± 0.86; LOAD 3.56 ± 0.77 L·min-1) or respiratory exchange ratio (CON 1.05 ± 0.06; LOAD 1.06 ± 0.04) during the 5-minute running economy bouts. There was an inverse (r = -0.42) but nonsignificant (p = 0.22) relationship between percent difference in body mass and percent difference in performance. Metabolic variable differentiation was not detectable at race pace, but 2.4 kg of proximal loading resulted in an approximately 4% acute performance impairment.

Urine Specific Gravity as a Practical Marker for Identifying Suboptimal Fluid Intake of Runners ∼12-hr Postexercise.

The legitimacy of urine specific gravity (USG) as a stand-alone measure to detect hydration status has recently been challenged. As an alternative to hydration status, the purpose of this study was to determine the diagnostic capability of using the traditional USG marker of >1.020 to detect insufficient recovery fluid consumption with consideration for moderate versus high sweat losses (2.00-2.99 or >3% body mass, respectively). Adequate recovery fluid intake was operationally defined as ≥100% beverage fluid intake plus food water from one or two meals and a snack. Runners (n = 59) provided 132 samples from five previous investigations in which USG was assessed 10-14 hr after 60-90 min runs in temperate-to-hot environments. Samples were collected after a meal (n = 58) and after waking (n = 74). When sweat losses exceeded 3% body mass (n = 60), the relationship between fluid replacement percentage and USG increased from r = -.55 to -.70. Correct diagnostic decision improved from 66.6 to 83.3%, and receiver operating characteristic area under the curve increased the diagnostic accuracy score from 0.76 to approaching excellent (0.86). Artifacts of significant prerun hyperhydration (eight of 15 samples has USG <1.005) may explain false positive diagnoses, while almost all (84%) cases of false positives were found when sweat losses were <3.0% of body mass. Evidence from this study suggests that euhydrated runners experiencing significant sweat losses who fail to reach adequate recovery fluid intake levels can be identified by USG irrespective of acute meal and fluid intake ∼12-hr postrun.

Fluid Retention and Utility of Practical Hydration Markers to Detect Three Levels of Recovery Fluid Intake in Male Runners.

Runners are unlikely to consume fluid during training bouts increasing the importance of recovery rehydration efforts. This study assessed urine specific gravity (USG) responses following runs in the heat with different recovery fluid intake volumes. Thirteen male runners completed 3 evening running sessions resulting in approximately 2,200 ± 300 ml of sweat loss (3.1 ± 0.4% body mass) followed by a standardized dinner and breakfast. Beverage fluid intake (pre/postbreakfast) equaled 1,565/2,093 ml (low; L), 2,065/2,593 ml (moderate; M) and 2,565/3,356 mL (high; H). Voids were collected in separate containers. Increased urine output resulted in no differences (p > .05) in absolute mean fluid retention for waking or first postbreakfast voids. Night void averages excluding the first void postrun (1.025 ± 0.008; 1.013 ± 0.008; 1.006 ± 0.003), first morning (1.024 ± 0.004; 1.015 ± 0.005; 1.014 ± 0.005), and postbreakfast (1.022 ± 0.007; 1.014 ± 0.007; 1.008 ± 0.003) USG were higher (p < .05) for L versus M and H respectively and more clearly differentiated fluid intake volume between L and M than color or thirst sensation. Waking (r = -0.66) and postbreakfast (r = -0.71) USG were both significantly correlated (p < .001) with fluid replacement percentage, but not absolute fluid retention. Fluid intake M was reported as most similar to normal consumption (5.6 ± 1.0 on 0-10 scale) after breakfast and equaled 122 ± 16% of sweat losses. Retention data suggests consumption above this level is not warranted or actually practiced by most runners drinking ad libitum, but that periodic prerun USG assessment may be useful for coaches to detect runners that habitually consume low levels of fluids between training bouts in warm seasons.

A Ketone Monoester with Carbohydrate Improves Cognitive Measures Postexercise, but Not Performance in Trained Females.

PURPOSE: The acute ingestion of a ketone monoester with the coingestion of a carbohydrate (KME + CHO) compared with carbohydrate (CHO) was investigated on cycling performance and cognitive performance in trained females. METHODS: Using a two condition, placebo-controlled, double-blinded and crossover design, 12 trained females (mean ± SD: age, 23 ± 3 yr; height, 1.64 ± 0.08 m; mass, 65.2 ± 12.7 kg) completed a baseline assessment of cognitive performance (psychomotor vigilance testing (PVT), task switching, and incongruent flanker), followed by 6 × 5-min intervals at 40%, 45%, 50%, 55%, 60%, and 65% of their maximal power output (W max ) and then a 10-km time trial, concluding with the same assessments of cognitive performance. Participants consumed either 375 mg·kg -1 body mass of KME with a 6% CHO solution (1 g·min -1 of exercise) or CHO alone, across three boluses (50:25:25). RESULTS: Blood ß-hydroxybutyrate concentrations averaged 1.80 ± 0.07 and 0.13 ± 0.01 mM during exercise in KME + CHO and CHO, respectively. Blood glucose decreased after drink 1 of KME + CHO (~15%; P = 0.01) but not CHO, and lactate concentrations were lower in KME + CHO at 50%, 55%, 60%, and 65% W max (all P < 0.05) compared with CHO. Despite these changes, no differences were found between conditions for time trial finishing times (KME + CHO, 29.7 ± 5.7 min; CHO, 29.6 ± 5.7 min; P = 0.92). However, only KME + CHO resulted in increases in psychomotor vigilance testing speed (~4%; P = 0.01) and faster reaction times (~14%; P < 0.01), speed (~15%; P < 0.01), and correct responses (~13%; P = 0.03) in the incongruent flanker during posttesting compared with CHO. CONCLUSIONS: The acute ingestion of a KME + CHO elevated blood ß-hydroxybutyrate and lowered glucose and lactate across multiple time points during exercise compared with CHO. Although these changes did not affect physical performance, several markers of cognitive performance were improved by the addition of a KME in trained females.

Influence of terminal RPE on session RPE.

Session rating of perceived exertion (RPE; SRPE), a convenient model for monitoring the overall perceived exertion of an exercise bout, is not well understood. The SRPE may be linked to final acute RPE before exercise cessation. This study investigated the potential link between terminal acute RPE (TRPE) and the SRPE using cycling trials of equated work. Fifteen subjects (age: 24.3 ± 5.1 years) completed a maximal exertion cycle trial followed by 2 (counterbalanced) 40-minute cycling trials at approximately 75% of individualized V[Combining Dot Above]O2max. By manipulating warm-up and cooldown, the trials were designed to result in a high TRPE (HITRPE) and low TRPE (LOTRPE). The heart rate (HR) and RPE were recorded every 5 minutes during exercise, with the SRPE recorded 20 minutes postexercise. The mean RPE (MeanRPE) during exercise (min 10-40 HITRPE and minutes 5-35 for LOTRPE) was calculated by averaging all RPE responses recorded during exercise at 75% V[Combining Dot Above]O2max. Two-way (trial × time) repeated measures analysis of variance and Bonferroni post hoc tests were used to compare the MeanRPE, SRPE, and TRPE. MeanRPE, HR, and power output (using paired t-test) for exercise at 75% V[Combining Dot Above]O2max did not differ (p > 0.05) between HITRPE and LOTRPE. The TRPE at minute 40 was significantly lower (p < 0.05) for LOTRPE (3.1 ± 2.6) vs. HITRPE (8.2 ± 1.7), no significant difference was found for SRPE (LOTRPE: 7.6 ± 2.0 vs. HITRPE 7.4 ± 1.7). The findings indicate that the SRPE was not linked to TRPE. Further research is warranted using various modalities to extend the understanding of potential mediating factors of SRPE.

24 h Hydration profile of collegiate soccer players training once versus twice per day in the heat.

This study examined 24-h hydration parameters among collegiate, male soccer players (n = 17) during twice (X2) and once (X1) per day practice schedules in the heat. Urine specific gravity (USG) and body mass were measured before morning practices, afternoon practice (X2)/team meeting (X1), and the next morning practices. Fluid intake, sweat losses, and urinary losses were assessed during each 24-h window. Pre-practice body mass or USG did not differ among the timepoints. Sweat losses differed among all practices (p < 0.05) and averaged approximately 2.181±0.693 (X2AM) 1.710±0.474 (X2PM), and 3.361±0.956 L (X1AM), but players averaged replacing >50% of sweat losses with fluid intake every practice. Fluid intake during and between practices from practice 1 to the afternoon practice for X2 resulted in a positive fluid balance for X2 (+0.446±0.916 L). However, higher sweat loss during the initial morning practice and lower relative fluid intake prior to the afternoon team meeting the following morning resulted in a negative fluid balance (-0.304±0.675 L; p < 0.05: Cohen's d = 0.94) over the same time period for X1. By the start of the next morning practice sessions, both X1 (+0.664±1.051 L) and X2 (+0.446±0.916 L) were in positive fluid balance, respectively. Ample fluid consumption opportunities, scaled down practice intensities during X2, and potentially intentional greater relative fluid intake during X2 training resulted in no difference in fluid shift versus an X1 schedule before the start of practices. The majority of players maintained fluid balance drinking ad libitum regardless of practice schedule.

Effects of 3 Weeks Yogic Breathing Techniques on Sub-maximal Running Responses.

This study investigated the influence of yoga breathing techniques (YBT) on physiological and perceptual responses during sub-maximal treadmill running. Runners (n = 21) of various fitness (VO2max 48.4 ± 9.5 ml/kg/min) were assigned to Yoga (YG) or control (CT) group before completing pre/post treadmill trials where velocity was self-selected to produce an RPE 4 and RPE 7 (10 min each). YG (n =11) practiced three styles of YBT (30 min/day, 6 days/wk) for 3 consecutive wks. Self-selected running velocity for YG improved significantly at both prescribed RPE 4 (pre 157.63 ± 26.20 M/min, post 181.02 ± 24.22 M/min, p = 0.01) and prescribed RPE 7 (pre 201.97 ± 31.28 M/min, post 222.68± 35.32 M/min, p = 0.01). VO2 at RPE 7 increased significantly (pre 42.6 ± 6.9 ml/kg/min, post 47.3 ± 6.2 ml/kg/min, p = 0.02), TV at RPE 7 (pre 1.81 ± 0.30, post 2.04 ± 0.41, p = 0.01), and MV at RPE 7 (pre 77.25 ± 12.42, post 91.23 ± 20.05, p = 0.01). The CT group showed no significant changes except for TV at RPE 7 (pre 1.9 ± 0.3, post 2.0 ± 0.3, p = 0.04). Current results suggest YBT positively influences running velocity regulation during self-selected running.

Runners greatly underestimate sweat losses before and after a 1-hr summer run.

The purpose of this study was to determine how accurately runners estimate their sweat losses. Male (n = 19) and female (n = 20) runners (41 ± 10 yr, VO2max 57 ± 9 ml · kg(-1) · min(-1) from the southeastern U.S. completed an ~1-hr run during late summer on a challenging outdoor road course (wet bulb globe temperature 24.1 ± 1.5 °C). Runs began at ~6:45 a.m. or p.m. Before and after running, participants filled race-aid-station paper cups with a volume of fluid they felt would be equivalent to their sweat losses. Total sweat losses and losses by percent body weight differed (p < .01) between men (1,797 ± 449 ml, 2.3% ± 0.6%) and women (1,155 ± 258 ml, 1.9% ± 0.4%). Postrun estimates (738 ± 470 ml) were lower (p < .001) than sweat losses (1,468 ± 484 ml), equaling underestimations of 50% ± 23%, with no differences in estimation accuracy by percentage between genders. Runners who reported measuring changes in pre- and postrun weight to assess sweat losses within the previous month (n = 9, -54% ± 18%) were no more accurate (p = .55) than runners who had not (n = 30, -48% ± 24%). These results suggest that inadequate fluid intake during runs or between runs may stem from underestimations of sweat losses and that runners who do assess sweat-loss changes may be making sweat-loss calculation errors or do not accurately translate changes in body weight to physical volumes of water.

Four Weeks of Hericium erinaceus Supplementation Does Not Impact Markers of Metabolic Flexibility or Cognition.

Hericium erinaceus (HE), also known as Lion's Mane mushroom, has been found to enhance cognition and metabolic flexibility in various animal models. To date however, only four studies exist in humans and none have evaluated the effects of HE on markers of metabolic flexibility or cognitive performance. A single-blind, placebo controlled, parallel-longitudinal study was used to determine the effects of HE on markers of metabolic flexibility and cognition. Twenty-four participants completed a graded exercise test on a cycle ergometer to analyze substrate oxidation rates and markers of cardiorespiratory fitness. Additionally, two dual-task challenges consisting of a Stroop Word Challenge interspersed with a Mental Arithmetic Challenge were performed, pre-post the graded exercise test, to evaluate markers of cognition in a pre-post fatigued state. Participants were stratified into two groups, receiving either 10 g of HE per day or placebo for 4-weeks in the form of two muffins identical in taste and appearance. Repeated-measures analysis of variance were conducted to evaluate potential interactions or main effects. Although group differences were noted at baseline, there were no significant interactions or main effects observed from HE ingestion for any dependent variable (all p > 0.05). Our data suggest that ingesting 10 g of HE per day for 4-weeks had no impact on metabolic flexibility and cognition in a college-age cohort. Due to the limited research on HE supplementation, future research is needed to establish an effective supplement dose and duration for potential physiological changes to be observed in humans.

The Cardiometabolic Health Benefits of Sauna Exposure in Individuals with High-Stress Occupations. A Mechanistic Review.

Components of the metabolic syndrome (i.e., hypertension, insulin resistance, obesity, atherosclerosis) are a leading cause of death in the United States and result in low-grade chronic inflammation, excessive oxidative stress, and the eventual development of cardiometabolic diseases (CMD). High-stress occupations (HSO: firefighters, police, military personnel, first responders, etc.) increase the risk of developing CMD because they expose individuals to chronic and multiple stressors (i.e., sleep deprivation, poor nutrition habits, lack of physical activity, psychological stress). Interestingly, heat exposure and, more specifically, sauna bathing have been shown to improve multiple markers of CMD, potentially acting as hormetic stressors, at the cellular level and in the whole organism. Therefore, sauna bathing might be a practical and alternative intervention for disease prevention for individuals with HSO. The purpose of this review is to detail the mechanisms and pathways involved in the response to both acute and chronic sauna bathing and collectively present sauna bathing as a potential treatment, in addition to current standard of care, for mitigating CMD to both clinicians and individuals serving in HSO.

Caffeinated Gum Does Not Influence RPE-Regulated Cadence in Recreationally-Active College Females Regardless of Habitual Caffeine Consumption.

Caffeine (CAF) has been extensively studied for its ergogenic and analgesic effects during exercise. However, the majority of these studies have been conducted in male populations. This study investigated the effects of acute CAF chewing gum on self-selected exercise intensity during a rating of perceived exertion (RPE) production trial in active females (n = 16, 21.0 ± 2.8 y). Data were also analyzed based on habitual CAF consumption level. Participants completed a V̇O2peak trial, followed by a familiarization and two randomized, triple-blinded experimental RPE production trials on an arm ergometer [clamped resistance, blinded to self-selected cadence (CAD)] with either CAF gum (300 mg; 4.8 ± 0.7 mg/kg-1 body mass) or placebo (PLA), at a prescribed RPE of 4 and 7 (10 min each). Self-selected CAD did not statistically differ (p > 0.05) between CAF or PLA for an RPE4 (37.7 ± 1.6 vs. 37.6 ± 1.6 rev·min-1) or RPE7 (42.9 ± 1.6 vs. 41.2 ± 1.7 rev·min-1), respectively. There were no statistical differences between treatment groups for any other variables, except restlessness rating which was significantly higher (3.5 vs. 2.2; p = 0.03, d = 0.64) for the CAF group compared to PLA. Secondary analysis revealed no statistical differences for any variables between habitual consumers of low (23 ± 20 mg/day) or mod/high (195 ± 93 mg/day) CAF. Our data support previous studies examining CAF in women across different testing modalities and suggest that regardless of habitual CAF consumption, females might require higher doses of CAF to replicate subjective and physiological responses commonly observed using similar RPE production protocols in male participants. These findings support the need for additional investigations into female physiological and perceptual responses following CAF ingestion.

Hydration Efficiency of a Protein Beverage Consumed in a Bolus vs. Metered Pattern during Recovery.

This study compared hydration efficiency of a carbohydrate-protein (CHO-PRO) beverage consumed in a bolus (BOL) vs. a metered (MET) drinking pattern during recovery from exercise induced hypohydration. Participants (n = 10) lost 2 - 2.5% of body mass from sweating during a morning exercise session. Participants were then assigned to either consume a carbohydrate/electrolyte/protein beverage in a bolus (BOL) or metered incremental consumption (MET) (counterbalanced) pattern post exercise. Total rehydration beverage administered during recovery equaled 125% of fluid lost during exercise. BOL was administered within the first hour of recovery, MET was administered 25% during the first 30 min, then 12.5% every 30 min for the next 4 hours. Mean (±SD) intake was 2475 ± 324 mL (MET) and 2525 ± 293 mL (BOL) (p = 0.22). Mean urine production was significantly greater for BOL (1167 ml ± 293 ml) than MET (730 ml ± 324 ml) (p = 0.003). Hydration efficiency (fluid ingested vs. fluid retained as percent) was significantly greater for MET (69.1 ± 15.4) than BOL (53.7 ± 9.7) (p = 0.004). Results indicate that, across a ~ 6-hour recovery, a metered drinking pattern improves fluid retention and therefore, hydration efficiency when a carbohydrate-protein beverage is consumed. More research is needed in paradigms characterized by unlimited fluid availability.

Effects of 3 Weeks Yogic Breathing Practice on Ventilation and Running Economy.

Yogic breathing techniques (Pranayama) positively impact respiratory function (RF) in non-endurance trained individuals. The purpose of this study investigated effects of routine Pranayama practice on RF, running economy (RE) and perceptual responses. A between subject's case-control study design was incorporated. Eleven runners practiced three styles of Pranayama (30 min/day 6 days/week) for 3 consecutive weeks (YG) and completed a VO2 max tests on a treadmill (trial 1), basic RF tests, and constant workload RE trials at 60, 70, and 80% VO2 max (trial 2 and 3). A control group (n = 10) (CT) completed the same pre - post testing without intervention. Pre vs. post values for resting forced vital capacity (FVC), peak expiratory flow rate (PEFR) and forced expiratory flow volume in one second (FEV1). Yoga improved FVC and FEV1, but did not significantly impact RE However, RPE-L for HIGH had an interaction (p < 0.05) showing a decrease for YG and an increase for CT. The current study suggests 3 weeks of yogic Pranayama fails to significantly impact RE, however some evidence indicates YG may positively alter perceptual responses at individually prescribed workloads. More work is needed to definitively establish benefits of YG for runners.

Effects of Three Modest Levels of Proximal Loading on Marathon Pace Running Economy.

This study examined the effect of modest increases in proximal body mass on running economy expressed as metabolic cost (MC). External loads of 1.6 (L), 2.4 (M), and 3.2 kg (H) were added to the anterior and posterior torso region of male (n = 18) and female (n = 18) runners using a double-layered compression garment with gel inserts. MC was evaluated using stoichiometry equations of data collected via indirect calorimetry. Data was collected during four, 5-min running bouts at marathon pace for the 3 load levels and an unloaded state (CON). When data from both sexes were combined, MC for CON (13.2 ± 2.7) was lower (p < 0.05) versus L (13.5 ± 2.6), M (13.6 ± 2.6), and H (13.7 ± 2.6 kcal/min), but L did not differ from CON when data was analyzed for each sex. Male runners exhibited stepped increases in MC across loads and a weak-moderate relationship (r = 0.37; p < 0.01) between percentage change in absolute MC and increased percent body mass. A prediction model for MC (Δ% kcal/min = 0.98(Δ% body mass) - 0.91; SEE = ± 2.5%) was developed. For female runners, L increased MC by ~3.5% above CON, but no differentiation was found among L, M, and H, limiting the development of a prediction equation for females. Modest increases in body mass can produce detectable and potentially important levels of running economy impairment, but the relationship between changes in body mass and RE are complex, particularly in regards to sex.