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1.
Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism.
Cell
; 137(7): 1235-46, 2009 Jun 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-19563756
2.
Model mice for 15q11-13 duplication syndrome exhibit late-onset obesity and altered lipid metabolism.
Hum Mol Genet
; 24(16): 4559-72, 2015 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26002101
3.
Recombinant Fusion Allergens, Cry j 1 and Cry j 2 from Japanese Cedar Pollen, Conjugated with Polyethylene Glycol Potentiate the Attenuation of Cry j 1-Specific IgE Production in Cry j 1-Sensitized Mice and Japanese Cedar Pollen Allergen-Sensitized Monkeys.
Int Arch Allergy Immunol
; 168(1): 32-43, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26524293
4.
Evaluation of [¹8F]MK-0911, a positron emission tomography (PET) tracer for opioid receptor-like 1 (ORL1), in rhesus monkey and human.
Neuroimage
; 68: 1-10, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23238431
5.
Synthesis, characterization, and monkey positron emission tomography (PET) studies of [18F]Y1-973, a PET tracer for the neuropeptide Y Y1 receptor.
Neuroimage
; 54(4): 2635-42, 2011 Feb 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21078401
6.
Synthesis, characterization, and monkey PET studies of [¹8F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435.
Synapse
; 65(2): 125-35, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-20524178
7.
Selective M3 muscarinic receptor antagonist inhibits small-cell lung carcinoma growth in a mouse orthotopic xenograft model.
J Pharmacol Sci
; 116(1): 81-8, 2011.
Artículo
en Inglés
| MEDLINE | ID: mdl-21512307
8.
Polymorphisms in Cha o 1 and Cha o 2, major allergens of Japanese cypress (Chamaecyparis obtusa) pollen from a restricted region in Japan.
PLoS One
; 16(12): e0261327, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34962964
9.
Regulation of spontaneous Ca(2+) spikes by metabotropic glutamate receptors in primary cultures of rat cortical neurons.
J Neurosci Res
; 88(10): 2252-62, 2010 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20209633
10.
Isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists.
Bioorg Med Chem Lett
; 20(2): 726-9, 2010 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20005101
11.
Unique antipsychotic activities of the selective metabotropic glutamate receptor 1 allosteric antagonist 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one.
J Pharmacol Exp Ther
; 330(1): 179-90, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19359526
12.
Cloning and characterization of the rhesus monkey nociceptin/orphanin FQ receptor.
Genes Genet Syst
; 84(5): 319-25, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20154418
13.
Synthesis and biological evaluation of imidazole derivatives as novel NOP/ORL1 receptor antagonists: exploration and optimization of alternative pyrazole structure.
Bioorg Med Chem Lett
; 19(16): 4611-6, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19604695
14.
Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist.
Bioorg Med Chem Lett
; 19(18): 5464-8, 2009 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19674894
15.
Discovery and biological profile of isoindolinone derivatives as novel metabotropic glutamate receptor 1 antagonists: a potential treatment for psychotic disorders.
Bioorg Med Chem Lett
; 19(18): 5310-3, 2009 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19692242
16.
Identification of MK-1925: a selective, orally active and brain-penetrable opioid receptor-like 1 (ORL1) antagonist.
Bioorg Med Chem Lett
; 19(16): 4729-32, 2009 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19564110
17.
Optimization of benzimidazole series as opioid receptor-like 1 (ORL1) antagonists: SAR study directed toward improvement of selectivity over hERG activity.
Bioorg Med Chem Lett
; 19(11): 3100-3, 2009 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19398200
18.
Discovery of novel arylpyrazole series as potent and selective opioid receptor-like 1 (ORL1) antagonists.
Bioorg Med Chem Lett
; 19(13): 3627-31, 2009 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19447610
19.
2-Cyclohexylcarbonylbenzimidazoles as potent, orally available and brain-penetrable opioid receptor-like 1 (ORL1) antagonists.
Bioorg Med Chem Lett
; 19(11): 3096-9, 2009 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19394217
20.
Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide].
J Pharmacol Exp Ther
; 326(2): 577-86, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18487514