Detalles de la búsqueda
1.
Modeling Pharmacokinetic Natural Product-Drug Interactions for Decision-Making: A NaPDI Center Recommended Approach.
Pharmacol Rev
; 73(2): 847-859, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33712517
2.
An Integrative Approach to Elucidate Mechanisms Underlying the Pharmacokinetic Goldenseal-Midazolam Interaction: Application of In Vitro Assays and Physiologically Based Pharmacokinetic Models to Understand Clinical Observations.
J Pharmacol Exp Ther
; 387(3): 252-264, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37541764
3.
A Physiologically-Based Pharmacokinetic Model for Cannabidiol in Healthy Adults, Hepatically-Impaired Adults, and Children.
Drug Metab Dispos
; 51(6): 743-752, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-36972999
4.
Translating Kratom-Drug Interactions: From Bedside to Bench and Back.
Drug Metab Dispos
; 51(8): 923-935, 2023 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-37286363
5.
Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice.
Drug Metab Dispos
; 51(11): 1483-1489, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37562957
6.
Fexofenadine Plasma Concentrations to Estimate Systemic Exposure in Healthy Adults Using a Limited Sampling Strategy with a Population Pharmacokinetic Approach.
Ther Drug Monit
; 45(4): 539-545, 2023 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36645711
7.
Developing a Knowledge Graph for Pharmacokinetic Natural Product-Drug Interactions.
J Biomed Inform
; 140: 104341, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36933632
8.
Limitations of fexofenadine limited sampling strategy using plasma concentrations and partial area under the concentration-time curve to estimate transporter activity in healthy adults.
Int J Clin Pharmacol Ther
; 61(6): 262-269, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-37042268
9.
Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes.
Drug Metab Dispos
; 50(4): 351-360, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35115300
10.
Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs.
Antimicrob Agents Chemother
; 65(4)2021 03 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33468464
11.
Refined Prediction of Pharmacokinetic Kratom-Drug Interactions: Time-Dependent Inhibition Considerations.
J Pharmacol Exp Ther
; 376(1): 64-73, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33093187
12.
Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin-drug interactions.
Phytother Res
; 35(6): 3286-3297, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-33587330
13.
Natural Products: Experimental Approaches to Elucidate Disposition Mechanisms and Predict Pharmacokinetic Drug Interactions.
Drug Metab Dispos
; 48(10): 956-962, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32816868
14.
Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450.
Drug Metab Dispos
; 48(10): 1008-1017, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32587099
15.
Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects.
Drug Metab Dispos
; 48(10): 1018-1027, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32591416
16.
A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies.
Drug Metab Dispos
; 48(10): 1104-1112, 2020 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-32601103
17.
"Natural" is not synonymous with "Safe": Toxicity of natural products alone and in combination with pharmaceutical agents.
Regul Toxicol Pharmacol
; 113: 104642, 2020 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-32197968
18.
Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach.
Nat Prod Rep
; 36(8): 1196-1221, 2019 08 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-30681109
19.
A Pharmacokinetic Natural Product-Disease-Drug Interaction: A Double Hit of Silymarin and Nonalcoholic Steatohepatitis on Hepatic Transporters in a Rat Model.
J Pharmacol Exp Ther
; 371(2): 385-393, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31420525
20.
Indinavir Increases Midazolam N-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach.
Drug Metab Dispos
; 47(7): 724-731, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-31028057