Asunto(s)
Dermatitis Alérgica por Contacto , Dermatitis Profesional , Humanos , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/diagnóstico , Dermatitis Profesional/etiología , Fenilendiaminas/efectos adversos , Goma , Pruebas del ParcheRESUMEN
BACKGROUND: Hand eczema (HE) is common and may follow a chronic disease course. So far, prospective studies investigating the risk factors for disease progression as a prerequisite for targeted prevention are scarce. OBJECTIVE: To evaluate the overall association of HE-associated factors with clinical and quality of life (QoL) improvement during a follow-up of 2 years. METHODS: Data of the prospective patient cohort (N = 199) followed by the Swiss chronic HE (CHE) registry on long-term patient management (CARPE-CH) were analysed by means of both classic regression and semantic map analyses. RESULTS: Both severity of HE and QoL significantly improved over the period of 2 years (P < .001). However, 20% of patients had moderate to severe HE after 2 years of follow-up. As factors associated with an unfavourable CHE clinical course and QoL, environmental exposures, male sex, occupational skin disease, job loss or change at baseline, allergic contact dermatitis, a chronic disease course, palmar localization and widespread eczema were identified. CONCLUSIONS: Analysis of prospective data from CARPE-CH shows a complex pattern of associations among variables as shown by semantic map and classic statistical analyses. Factors related to occupational exposure had the highest impact on CHE.
Asunto(s)
Dermatitis Profesional/epidemiología , Eccema/epidemiología , Dermatosis de la Mano/epidemiología , Calidad de Vida , Sistema de Registros , Enfermedad Crónica/epidemiología , Humanos , Exposición Profesional/estadística & datos numéricos , Estudios Prospectivos , Índice de Severidad de la Enfermedad , Suiza/epidemiologíaAsunto(s)
Dermatitis Alérgica por Contacto , Dermatitis Profesional , Dermatosis de la Mano , Dermatitis Alérgica por Contacto/diagnóstico , Dermatitis Alérgica por Contacto/etiología , Dermatitis Profesional/diagnóstico , Dermatitis Profesional/etiología , Guantes Protectores/efectos adversos , Dermatosis de la Mano/inducido químicamente , Humanos , Nitrilos/efectos adversos , TiazolesAsunto(s)
Dermatitis Profesional/etiología , Dermatosis de la Mano/inducido químicamente , Desinfectantes para las Manos/efectos adversos , Personal de Salud , Dermatitis Alérgica por Contacto/etiología , Dermatitis Irritante/etiología , Femenino , Humanos , Masculino , Suiza , Centros de Atención TerciariaRESUMEN
Isothiazolinone is known to be a sensitizer and a frequent cause of contact dermatitis in adults. Cases of contact dermatitis have also recently been reported in children. Derivatives of isothiazolinone, such as methylisothiazolinone (MI) and methylchloroisothiazolinone (MCI), are commonly used in the care products of babies and children. This allergen should not be missed.