Evaluation of Size of the Condyle in Vertical and Anteroposterior Skeletal Conditions with the Help of Cone-beam Computed Tomography.

AIM: Evaluation of size of the condyle in various vertical and anteroposterior skeletal conditions with the help of cone-beam computed tomography (CBCT). METHODS AND MATERIALS: In this study, 266 study participants were included consisting of 112 males and 144 females. The study participants were categorized as class I when -1° ≤ A point-nasion-B point angle (ANB) < 4°, class II when ANB ≥ 4°, and class III when ANB < -1°. The study participants were categorized as hypodivergent when the mandibular plane (MP) ≤ 23°, normodivergent when 23° < MP < 30°, and hyperdivergent when MP ≥ 30°. CBCT images were obtained for each subject and measurement of length, width, and height of the condyle was carried out. The data were collected and analysis of covariance test (ANCOVA) was used for statistical analysis. Statistical significance was adjusted at p ≤ 0.05. RESULTS: The size of the condyle was smaller in females. The length of the condyle was similar in different anteroposterior and vertical positions with no significant difference. The width of the condyle and the height of the condyle were greatest in class III anteroposterior condition while they were lowest in class I condition. The width and height of the condyle were greatest in hypodivergent condition while they were lowest in hyperdivergent condition. CONCLUSION: It was concluded that the height and width of the condyle vary considerably in different vertical and anteroposterior skeletal patterns and the size of the condyle was smaller in women as compared with men. CLINICAL SIGNIFICANCE: The position of the condyle and its morphology are important features that constitute an important part of orthodontic treatment planning. The skeletal pattern of the patient has also an important effect on the diagnosis, planning of treatment, and prognosis in the orthodontic treatment.

Role of Selective Serotonin Reuptake Inhibitors in Prognosis Dental Implants: A Retrospective Study.

BACKGROUND: Many recent research shows that antidepressants interfere with the osseointegration of implants. The main purpose of this study was to determine the association between selective serotonin reuptake inhibitors (SSRI) and dental implant failure. MATERIALS AND METHODOLOGY: A retrospective study consisted of 410 patients (720 dental implants). Patients' records were used to retrieve the history of SSRI use and medication. The study consists of two groups. Group I (SSRI users) consisted of 128 patients (245 dental implants) patients, whereas Group II (non-SSRI users) was formed by 282 patients (475 dental implants). The implant failure rate was evaluated and statistically examined using the Chi-square test. RESULTS: Group I had 30 implant failures with 13 (12%) males and 14 (11.8%) females, whereas Group II had 28 implant failures with 12 (6.3%) males and 16 (5.6%) females. In Group I, 26% of the implants failed in the age group >50 years, whereas it was 10.4% in Group II. However, in the age group <50 years, it was 6% and 4.2% Groups I and II, respectively. Group I shows that out of 40 implants in diabetic patients, 12 had failure, whereas in Group II, out of 32 implants placed in diabetics, 7 had failure. In smokers, 48% of the implants failed in Group I, and 29% in group II. In non-smokers the failure was seen in 7.7% cases in Group I and 2.1% cases in Group II. The difference was statistically significant (P < 0.05). CONCLUSION: The usage of SSRIs is associated with an increased rate of implant failure. It has a deleterious effect on bone remodeling and leads to excessive osteoporosis.

Evaluation of Preoperative Salivary Cortisol Level in Patients Undergoing Major Maxillofacial Surgery.

AIM: The main purpose of the study was to compare the preoperative salivary cortisol levels 3 days before the major surgery under general anesthesia and to compare it with the patients undergoing extraction under local anesthesia. MATERIALS AND METHODS: Forty-two patients were undergoing major surgery and 42 age- and sex-matched patients undergoing dental extraction were included and their salivary cortisol levels were analyzed before and after the dental procedure. RESULTS: Results showed that there is a significant increase in the mean salivary cortisol concentration after extraction (23.7 ± 9.2) than before extraction (18.9 ± 23.7) in the study group (P = 0.015) as well as in the control group. The comparison between salivary cortisol in the study group before (18.9 ± 23.7) and after (23.7 ± 9.2) surgery was significantly higher than the control group (15.2 ± 5.5) (P = 0.013 and 0.005), respectively. CONCLUSION: We have concluded from this study that the salivary cortisol level shows a significant increase on the day of surgery.

Antibacterial and Antifungal Efficacy of Platelet-Rich Fibrin and Platelet-Rich Fibrin Matrix against Root Canal Microflora.

BACKGROUND: Binding of such proteins with a developing fibrin mesh or to the extracellular matrix has the ability to create chemotactic gradients aiding the recruitment of stem cells, thereby, stimulating cell migration and differentiation this may promotes repair and regeneration. There is a unique concept in platelet concentrates called platelet-rich fibrin matrix (PRFM) which is processed using higher attraction without the utilization of bovine thrombin. AIM AND OBJECTIVES: The aim of this study is to evaluate the antibacterial and antifungal effects of platelet-rich fibrin (PRF) and PRFM against root canal microflora. MATERIALS AND METHODS: Blood samples were taken from 20 adults, age ranging from 20 to 40 years who were systemically healthy, nonsmokers with no symptoms of infection, or on antibiotics at least 3 months before experiments. The procedures and the protocols involved in the study were accepted by the Institutional Ethical Committee. Written informed consent was obtained from the donors and patients. Approximately 10 ml of blood was collected from each donor. 5 ml of blood was used for the preparation of PRF and 5 ml for PRFM. RESULTS: The antifungal scores among the groups. The highest antifungal scores were seen in metapex followed by PRF and PRFM group. Kruskal-Wallis test was applied to check the statistical difference among the groups, and there was a statistically significant difference seen among the groups (P = 0.00). The antibacterial scores among the groups. The highest antibacterial scores were seen in Metapex followed by PRF group and PRFM group Kruskal-Wallis test was applied to check the statistical difference among the groups, and there was a statistically significant difference seen among the groups. CONCLUSION: PRF demonstrated antibacterial activity against passage isolates but had no antifungal efficacy. This antibacterial property may be a valuable adjunct when using PRF for regenerative procedures in endodontics. Both PRF and PRFM have to be analyzed for antimicrobial properties for extended duration and various other clinical strains with larger sample size.

Comparative Evaluation of Internal Margin Adaptation and Integrity of Class I Preparations using Two Composites: An In Vitro Study.

AIM AND OBJECTIVES: The aim of this study is to evaluate the internal margin adaptation and integrity of Class 1 preparations using two composites types (bulk fill/conventional) with two placement methods (4/2 mm increments). MATERIALS AND METHODS: Class 1 preparations of 4 mm × 4 mm dimensions were made on 30 extracted human mandibular molars. They were randomly divided into three groups; among them, in Group 1 (n = 10), cavities were filled with SureFil SDR Bulk Fill, Group 2 (n = 10) cavities were filled with Filtek Bulk Fill of 4 mm increments in both groups, and in Group 3 (n = 10), cavities were filled with conventional composite Filtek Z350 with 2 mm increments. Samples were sectioned occlusogingivally. Then, dye was on internal margins, and images of each specimen were recorded using a digital camera to evaluate the marginal integrity and adaptation of restorative material to the tooth surface with image analysis software. Then, collected data were put under the statistical analysis with analysis of variance test and post hoc Tukey's test. RESULTS: There was no significant difference in overall dye penetration in bulk fill and conventional (incremental fill) composite resins; however, when dye penetration was evaluated at different locations, within enamel and mid-dentin, significantly more gap-free margins were found than at the pulpal interface. Filtek Bulk Fill and conventional composite (Filtek Z350) showed comparatively more dye penetration toward the pulpal interface compared to SDR Bulk Fill. CONCLUSION: There were no significant differences in percentage of gap-free margins between fill types for any of the composite materials. The proportions of gap-free margin were less at the pulpal interface and mid-dentin portions and enamel when filled with 4 and 2 mm increments.