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Artículo en Inglés | MEDLINE | ID: mdl-6441265

RESUMEN

A total of 184 men with uncomplicated gonococcal urethritis were treated with a single oral dose of rifampicin 900 mg and erythromycin stearate 1 gm. The cure rate on day 3 was 95.1%, 175 were cured and 9 failed (4.9%). Of all the Neisseria gonorrhoeae isolated, 86 were PPNG (46.7%). There was no difference in failure rate among patients with PPNG or with non-PPNG. With the exception of self-limited gastrointestinal disturbance, side effects were minimal. The value of this combination for the treatment of uncomplicated gonococcal urethritis in men is promising and deserves further study.


Asunto(s)
Eritromicina/análogos & derivados , Gonorrea/tratamiento farmacológico , Rifampin/uso terapéutico , Uretritis/tratamiento farmacológico , Adolescente , Adulto , Anciano , Ampicilina/uso terapéutico , Ensayos Clínicos como Asunto , Costos y Análisis de Costo , Quimioterapia Combinada , Eritromicina/uso terapéutico , Humanos , Masculino , Persona de Mediana Edad , Neisseria gonorrhoeae/efectos de los fármacos , Resistencia a las Penicilinas , Probenecid/uso terapéutico , Tailandia
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