[Antiarrhythmic active amidinohydrazones of substituted benzophenones. 4. The photoisomerization of (Z)- and (E)-2-amino-5-chlorobenzophenone amidinohydrazones and the corresponding (E)-N-phenylamidinohydrazone]. / Antiarrhythmisch wirksame Amidinohydrazone substituierter Benzophenone. 4. Mitteilung: Untersuchungen zur Photoisomerisierung von (Z)- und (E)-2-Amino-5-chlorbenzophenonamidinohydrazon sowie des entsprechenden (E)-N-Phenylamidinohydrazons.

The title compounds undergo a photoisomerization by irradiation. If the E-isomers are irradiated by light of a wavelength of an absorption maximum typical for them, they can be converted quantitatively to the corresponding Z-isomers. In case that the synthesis of analogs of the title compounds give only one configurational isomer, sometimes the missing one can be obtained by photoisomerization.

[Synthesis and analgesic effect of 2-aryliminomethylquinolines]. / Synthese und analgetische Wirkung von 2-Aryliminomethylchinolinen.

2-Aryliminomethylquinolines were synthesized by the condensation of quinoline-2-carbaldehyde with the corresponding anilines. The compounds were evaluated for analgesic activity using the acetic acid writhing test. Some of them showed significant inhibition of the writhing syndrome. The most potent compound 3b was approximately as active as aminophenazone in the writhing and the hot-plate method.