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1.
Phys Rev Lett ; 131(5): 050401, 2023 Aug 04.
Artículo en Inglés | MEDLINE | ID: mdl-37595229

RESUMEN

Gauge theory and thermalization are both topics of essential importance for modern quantum science and technology. The recently realized atomic quantum simulator for lattice gauge theories provides a unique opportunity for studying thermalization in gauge theory, in which theoretical studies have shown that quantum thermalization can signal the quantum phase transition. Nevertheless, the experimental study remains a challenge to accurately determine the critical point and controllably explore the thermalization dynamics due to the lack of techniques for locally manipulating and detecting matter and gauge fields. We report an experimental investigation of the quantum criticality in the lattice gauge theory from both equilibrium and nonequilibrium thermalization perspectives, with the help of the single-site addressing and atom-number-resolved detection capabilities. We accurately determine the quantum critical point and observe that the Néel state thermalizes only in the critical regime. This result manifests the interplay between quantum many-body scars, quantum criticality, and symmetry breaking.

2.
Phys Rev Lett ; 131(7): 073401, 2023 Aug 18.
Artículo en Inglés | MEDLINE | ID: mdl-37656862

RESUMEN

Ultracold atoms in optical lattices form a competitive candidate for quantum computation owing to the excellent coherence properties, the highly parallel operations over spins, and the ultralow entropy achieved in qubit arrays. For this, a massive number of parallel entangled atom pairs have been realized in superlattices. However, the more formidable challenge is to scale up and detect multipartite entanglement, the basic resource for quantum computation, due to the lack of manipulations over local atomic spins in retroreflected bichromatic superlattices. In this Letter, we realize the functional building blocks in quantum-gate-based architecture by developing a cross-angle spin-dependent optical superlattice for implementing layers of quantum gates over moderately separated atoms incorporated with a quantum gas microscope for single-atom manipulation and detection. Bell states with a fidelity of 95.6(5)% and a lifetime of 2.20±0.13 s are prepared in parallel, and then connected to multipartite entangled states of one-dimensional ten-atom chains and two-dimensional plaquettes of 2×4 atoms. The multipartite entanglement is further verified with full bipartite nonseparability criteria. This offers a new platform toward scalable quantum computation and simulation.

3.
Zool Res ; 44(5): 837-847, 2023 Sep 18.
Artículo en Inglés | MEDLINE | ID: mdl-37501399

RESUMEN

The common marmoset ( Callithrix jacchus) has emerged as a valuable nonhuman primate model in biomedical research with the recent release of high-quality reference genome assemblies. Epileptic marmosets have been independently reported in two Asian primate research centers. Nevertheless, the population genetics within these primate centers and the specific genetic variants associated with epilepsy in marmosets have not yet been elucidated. Here, we characterized the genetic relationships and risk variants for epilepsy in 41 samples from two epileptic marmoset pedigrees using whole-genome sequencing. We identified 14 558 184 single nucleotide polymorphisms (SNPs) from the 41 samples and found higher chimerism levels in blood samples than in fingernail samples. Genetic analysis showed fourth-degree of relatedness among marmosets at the primate centers. In addition, SNP and copy number variation (CNV) analyses suggested that the WW domain-containing oxidoreductase ( WWOX) and Tyrosine-protein phosphatase nonreceptor type 21 ( PTPN21) genes may be associated with epilepsy in marmosets. Notably, KCTD18-like gene deletion was more common in epileptic marmosets than control marmosets. This study provides valuable population genomic resources for marmosets in two Asian primate centers. Genetic analyses identified a reasonable breeding strategy for genetic diversity maintenance in the two centers, while the case-control study revealed potential risk genes/variants associated with epilepsy in marmosets.


Asunto(s)
Callithrix , Epilepsia , Animales , Callithrix/genética , Estudios de Casos y Controles , Variaciones en el Número de Copia de ADN , Genética de Población , Epilepsia/veterinaria
4.
Rev Sci Instrum ; 93(12): 123002, 2022 Dec 01.
Artículo en Inglés | MEDLINE | ID: mdl-36586898

RESUMEN

Optical lattices for coherently manipulating ultracold atoms demand high-power, low-noise, narrow-line-width, and continuous-wave lasers. Here, we report the implementation of a 30 W 532 nm low-noise laser by second harmonic generation from a 1064 nm fiber laser, which is capable to generate optical lattices for a quantum gas microscope of Rb87 atoms. The overall conversion efficiency is 59% at an input power of 51 W with a lithium triborate crystal coupled to a ring cavity. The relative intensity noise of the output laser is suppressed to -120 dBc/Hz in the range of 10 Hz-100 kHz with a high dynamic range of over 50 dB, which is suitable for long-term trapping and coherent manipulation of the quantum gases.

5.
Rev Sci Instrum ; 92(8): 083202, 2021 Aug 01.
Artículo en Inglés | MEDLINE | ID: mdl-34470382

RESUMEN

Low-noise, high-power 532-nm lasers are of great interest in many scientific research studies, such as gravitational wave detection and ultracold atom experiments. In particular, in the experiments of quantum gas microscopy, a large power of laser is necessary during the imaging process, while low noise is important for preventing the atoms from being heated up. In this work, we report on the generation of such a 532-nm continuous-wave laser by coherently combining two laser beams produced by single-pass second-harmonic generation. The power of the combined laser is up to 17 W. With the help of intensity stabilization, we are able to suppress the relative intensity noise to below -120 dBc/Hz. The generated laser satisfies the experimental requirements for integrating optical superlattices with a quantum gas microscope.

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