Detalles de la búsqueda
1.
Boron-containing carbonic anhydrases inhibitors.
Bioorg Chem
; 143: 106976, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38000350
2.
1,5-Benzodiazepines as a platform for the design of carbonic anhydrase inhibitors.
Arch Pharm (Weinheim)
; 355(3): e2100405, 2022 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-34862650
3.
Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase.
J Enzyme Inhib Med Chem
; 36(1): 561-580, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-33615947
4.
Design, synthesis, in vitro inhibition and toxicological evaluation of human carbonic anhydrases I, II and IX inhibitors in 5-nitroimidazole series.
J Enzyme Inhib Med Chem
; 35(1): 109-117, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31687859
5.
A Novel Inhibitor of Carbonic Anhydrases Prevents Hypoxia-Induced TNBC Cell Plasticity.
Int J Mol Sci
; 21(21)2020 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33182416
6.
Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation.
Molecules
; 25(10)2020 May 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-32443462
7.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Molecules
; 25(13)2020 Jun 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32605268
8.
N-aryl-N'-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties.
Bioorg Chem
; 89: 103033, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31212085
9.
(Hetero)aryl substituted thiazol-2,4-yl scaffold as human carbonic anhydrase I, II, VII and XIV activators.
J Enzyme Inhib Med Chem
; 34(1): 224-229, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30734616
10.
Novel Re(I) tricarbonyl coordination compounds based on 2-pyridyl-1,2,3-triazole derivatives bearing a 4-amino-substituted benzenesulfonamide arm: synthesis, crystal structure, computational studies and inhibitory activity against carbonic anhydrase I, II, and IX isoforms.
J Enzyme Inhib Med Chem
; 34(1): 773-782, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30843736
11.
Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity.
J Enzyme Inhib Med Chem
; 34(1): 1498-1505, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-31423863
12.
Multivalent Carbonic Anhydrases Inhibitors.
Int J Mol Sci
; 20(21)2019 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-31661796
13.
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-6.
Molecules
; 25(1)2019 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-31905602
14.
Carbonic anhydrases from Trypanosoma cruzi and Leishmania donovani chagasi are inhibited by benzoxaboroles.
J Enzyme Inhib Med Chem
; 33(1): 286-289, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29278948
15.
Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes.
J Enzyme Inhib Med Chem
; 33(1): 1064-1073, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-29909747
16.
Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial ß-Carbonic Anhydrases: An Update on In Vitro and In Vivo Studies.
Molecules
; 23(11)2018 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30413024
17.
Polyhedral Oligomeric Silsesquioxane (POSS) Bearing Glyoxylic Aldehyde as Clickable Platform Towards Multivalent Conjugates.
Chemistry
; 23(71): 17867-17869, 2017 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-28892198
18.
Effective Access to Multivalent Inhibitors of Carbonic Anhydrases Promoted by Peptide Bioconjugation.
Chemistry
; 23(28): 6788-6794, 2017 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-28225196
19.
Anion inhibitors of the ß-carbonic anhydrase from the pathogenic bacterium responsible of tularemia, Francisella tularensis.
Bioorg Med Chem
; 25(17): 4800-4804, 2017 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28754318
20.
Brucella suis carbonic anhydrases and their inhibitors: Towards alternative antibiotics?
J Enzyme Inhib Med Chem
; 32(1): 683-687, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-28274160